Welcome and Update on Working Group Acitivities - Global Obesity Guidelines

Pubertal Development in Chinese Children and the Impact of Overnutrition, Lifestyle, and Perinatal Factors

Early growth trajectories in chidlren with genetic obesity. A European collaboration project

The CEW Clinic Concept

Childhood obesity in 2024 - shortlist of highlights

Immunological effects of gender affirming hormone treatment

Mental health/psychosocial outcomes versus mental health and brain effects

CORE ENDOCRINE REGISTRY: transgender module – preliminary data and future plans

Genetics of POI

Clinical management

Fertility preservation in girls

Welcome

News and doubts around growth and puberty therapy

Beyond growth and puberty issues in girls with TS

Challenges from the adult endocrinologist perspective

To present multi-central experience/data and invite to prospective study

Round Table/Discussion

Update on Working Group Activities

Regulation of the Epiphyseal Stem Cells

Osteogenesis imperfecta, update and the OI XIV Animal model

A case of osteogenesis imperfecta with Antonella Forlio’s expert opinion

A rare cause of 46, XY gonadal dysgenesis: Case presentation

Partial gonadal dysgenesis due to chromosomal mosaicism – a challenging case

Novel insights into the diagnosis of gonadal dysgnesis: findings from the 46,XY gonadal dysgenesis study based on the I-DSD Registry

Pathophysiology and Management of Dysgenetic Gonads

Research and innovation in nursing

Transition in endocrinology - the challenges - change to Complications after cancer treatment

Impact of GH on DNA damage

Vascular reactivity and morbidity in DSD

Novel mechanisms leading to DSD (genomic, digenic/ollogenic and non-coding variation)

Hypospadias - surgery and beyond

Phosphate sensing in normal physiology and disease

Advances in FGF 23 related disorders

PTH Resistance Syndromes

National UK Guidelines for the Management of Paediatric Craniopharyngioma

Use of MC4R agonist in hypothalamic obesity

Proton Beam Therapy in childhood brain tumours

Use of Verapamil in newly diagnosed T1D

Use of GLP1 receptor agonists in Wolfram syndrome

Statins and Cardiovascular risk in T1D

Type 2 Diabetes, Metabolic Syndrome and Lipids

Global Health for the Paediatric Endocrinologist

Growth and Growth Factors

Puberty

Adrenals

Perceptions and Experiences of PDSNs on Different Hybrid Closed Loop Systems (HCLS) across Wales

Evaluating Glucose-6-Phosphate Dehydrogenase Enzyme Activity In Children With Type 1 Diabetes Mellitus.

Akkermansia muciniphila induces immune homeostasis in type 1 diabetic mice by up-regulating CD4 + FoxP3 + Treg expression.

Children born small for gestational age (SGA) under growth hormone treatment have similarly impaired glucose-insulin metabolism as children with obesity

Evaluation of Arterial Stiffness in Children with Type 1 Diabetes Mellitus Using Speckle Tracking Carotid Strain Ultrasonography: Do Atherosclerotic Changes Begin in Childhood?

METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE AND ITS ASSOCIATION WITH GLYCEMIC CONTROL METRICS IN CHILDREN AND ADOLESCENTS WITH TYPE 1 DIABETES: AN EXPLORATORY STUDY

Bone and Body Composition after one year of Vosorotide treatment in children with Achondroplasia: a longitudinal prospective study.

Microarchitectural Alterations in Children with Rheumatological conditions on Long‑term Glucocorticoid Treatment

Optimizing the Growth Outcome follow up in Hypophosphatemic Rickets Treated with Burosumab: The Critical Role of Auxological Measurements

CYP24A1 MUTATIONS:, CLINICAL AND LABORATORY FEATURES IN PATIENTS PRESENTING WITH HYPERCALCEMIA

Prediction of residual growth potential in adolescent boys by linear regression modeling based on the radiomics features extracted by knee DR images and clinical characteristics

Comparison of two automated bone age evaluation methods in pediatric patients with growth and puberty disorders

DNA Methylation profiles in girls with anorexia nervosa and amenorrhea: a pilot study

Results from a targeted hypopituitarism gene panel in patients with variable congenital hypopituitarism identifies variants in known and novel candidate genes.

Analysis of the expression levels of spexin and kisspeptin in serum, ovarian tissue and white adipose tissue as related to pubertal status and metabolic surrogates of puberty in female albino Wistar rats

Longitudinal Changes in Serum DLK1 Concentrations During Pubertal Transition in Healthy Girls and in girls with Precocious Puberty during GnRHa treatment

Long-Term Health Outcomes of Delayed Puberty in Males: A Comprehensive Population-Based Study

Final Height and Endocrine Complications in Children with Pilocytic Astrocytomas: A Retrospective Study

Screening for Adrenal Insufficiency in Children by Home Waking Salivary Cortisone testing

Salivary cortisol and cortisone is related to age

Differences and similarities in salivary diurnal adrenal hormones in monozygotic twins with intra-twin birthweight-differences

Serum cortisol correlates strongly with salivary cortisol and cortisone in girls and boys, and across all ages

Ontogenesis of the urinary steroid metabolome in infancy assessed by gas chromatography/mass spectrometry (GC-MS)

Machine Learning-Based Decision Tree Model for the Diagnosis of Congenital Disorders of Adrenal Steroidogenesis Using LC-MS/MS-based Plasma Steroid Hormone Profiles

ABOUT CARING FOR PATIENTS AND UNDERSTANDING THEIR PATHWAYS: 10 YEARS OF ‘THE ROTTERDAM CENTRE FOR ADULTS WITH RARE GENETIC SYNDROMES’

The development and validation of Bone age-guided Interpretation of Growth (BIG), a web-based tool for the guidance of evaluation of children and adolescents with growth disorders.

Neuroradiological Findings in Noonan Syndrome: a multicentric Italian study

Analysis of growth patterns in Klinefelter syndrome using the QEPS growth model

Searching for associated dysmorphic and cardiac abnormalities in youth tall basketball players

Pubertal induction in girls with Turner syndrome – retrospective data from the International TS registry

Does Type 1 Diabetes Effect Left Ventricular Function in Children? Evaluation with Treadmill Exercise Stress Echocardiography

EFFECT OF HYDROXYCHLOROQUINE THERAPY IN NEWLY DIAGNOSED TYPE 1 DIABETES: A RANDOMISED, DOUBLE-BLIND, PLACEBO-CONTROL PILOT TRIAL

A Non-Invasive Diagnostic Tool for Early Detection of Microvascular Alterations in Children with Type 1 Diabetes Mellitus: Nail-Fold Capillaroscopy

A personalized approach to classify the degree of liver insulin resistance in children with obesity

The Side-Effects of Lanreotide in Children with Congenital Hyperinsulinism (CHI): A Decade-long Exploration

Comprehensive rescreening of the known congenital hyperinsulinism genes provides a new genetic diagnosis for 18% of the Finnish cohort

A highly selective FGFR3 inhibitor alleviates achondroplasia symptoms and restores chondrocyte growth in mice model

Therapeutic Effects of Human Bone Marrow Mesenchymal Stem Cells Derived Exosomes on Glucocorticoid-Induced Osteoporosis: In Vitro Model

Molecular mechanism of FBN1 variants result to acromicric dysplasia by mechano-transduction

Analysis of baseline data from the SUNFLOWER longitudinal, observational cohort study of patients with XLH: relationship between various complications and QOL

Bone health in adolescents with cow’s milk allergy during infancy

Expansion of the CrescNet Registry Achondroplasia Module: Real-World Demographic Data and Outcomes After up to 2 Years of Vosoritide Treatment

The Effects of Blue Light Exposure on the Epiphyseal Plate and IGF1 - IGFBP3 Expression in Rats

Disruption of the Wnt-antagonist APC in the pituitary stem cells is a driver of adamantinomatous craniopharyngioma

Analysis of clinical factors affecting retinal ganglion cell complex thickness reduction in patients with childhood‑onset craniopharyngioma.

The spectrum of Endocrinopathies in Children with Ectopic Posterior Pituitary (EPP) correlates with the severity of associated hypothalamo-pituitary abnormalities on imaging: a decade long experience from two tertiary centers.

Screening for First Morning Voided (FMV) Urinary Gonadotropin (Gn) in Children with Normal and Precocious Puberty (PP): A Prospective, Multi-Center, Large-Sample based Study in China

Adolescent Acne: Association to Sex, Age, Pubertal Stage and Circulating Concentrations of Testosterone and DHT

Real world data analysis of contemporary therapy and its association to anthropometric outcomes in 1500 patients with congenital adrenal hyperplasia (CAH).

11-oxygenated androgens are abundantly produced by first and second-trimester foetal adrenal glands in ex vivo culture

Plasma reference values for C19 oxy-steroids, 11-keto testosterone and 11-keto androstenedione in a paediatric cohort

Crinecerfont, a Corticotropin-Releasing Factor Type 1 Receptor (CRF1) Antagonist, Reduced Excess Adrenal Androgens and Glucocorticoid Doses in Children and Adolescents with Classic Congenital Adrenal Hyperplasia: Results from CAHtalystTM Pediatric

3D printed, personalized hydrocortisone for hypocortisolemia.

Comparative Efficacy of Modified-Release versus Conventional Hydrocortisone Treatment in Adolescents and Young Adults with Congenital Adrenal Hyperplasia: A Retrospective Observational Study

A homozygous variant in ZSWIM6 causes short stature, microcephaly and developmental delay

The pathogenesis of Noonan syndrome and associated growth restriction is modulated by NOC2L, a novel interactor of LZTR1 leading to impaired p53 signalling

Gene expression of monosomy X during human development reveals potential mechanisms in Turner syndrome

Predictors of short stature at age 6-7 years in Israeli children

Phase 2 Trial of Vosoritide Use in patients with Hypochondroplasia: Pharmacokinetic/ Pharmacodynamic analysis from 12 Month Data

First line treatment evaluation in patients with severe primary insulin-like growth factor 1 deficiency (SPIGFD): Data from the Global Increlex® Registry

How do I...Use Bisphosphonates

How do I...Handle GLP-1 analogue treatment in adolescents with obesity

How do I...Manage the infant with hypoglycaemia

Addressing Inequalities in Child Health. Lessons from the UK policy experiments in poverty and adversity

Genetic Testing in Hypogonadism

Management of Lipodystrophy

Pharmacological treatment options for adolescents with Obesity

Closed loop in the very young

Relevance of single cell analysis and spatial transcriptomics for endocrine research to unravel new mechanisms?

Adipogenic Hits on Kids

Managing difficult menstrual periods

Management of sodium and water regulation disorders

Diagnosis and Management of PCOS

The Diagnosis & Management of Rickets in the 21st Century

Management of Lipodystrophy

Should we restrict height in tall stature? - FOR

Should we restrict height in tall stature? - AGAINST

Endocrine disrupting effects of over-the-counter mild analgesics such as paracetamol in humans

Prenatal Exposure to Over-the-Counter Antifugal Drugs Affects Fetal Steroidogenesis and is Associated with Persistent Effects in Children

Effect of EDCs on the hypothalamic regulation of energy homeostasis and GnRH activity

Frequency of genetic variants in a population with early-onset obesity: a single center experience

Genetic Diagnostic Yield of Obesity

Identification and clinical characterization of new patients with novel monogenic agouti-like obesity trait

Investigation of GNAS Variations as Causes of Monogenic Obesity in Qatar: An Integrative Approach Utilizing In Silico, In Vivo, and In Vitro Studies

GRB10 METHYLATION IN UMBILICAL CORD ASSOCIATES POSTNATALLY WITH OBESITY IN HEALTHY CHILDREN

POTENTIAL ROLE OF ASPG METHYLATION AS A BIOMARKER OF CHILDHOOD OBESITY

Understanding the molecular basis of short stature in Fanconi Anemia: Impact of pappalysins and stanniocalcins on IGF-I bioavailability

Time-Restricted Feeding Restored Growth Hormone Pulsatile Profile in LEAP-2 KO Mice with High Fat Diet

Incidence of false positive results of growth hormone stimulation tests in children with short stature – from theoretical background to clinical approach

Use of iSYS-IDS IGF1-Assay Normative Data as a STANDARD in the Diagnosis of Pediatric Growth Hormone Deficiency

HEALTH-RELATED QUALITY OF LIFE AT MID-PUBERTY IN ADOLESCENTS WITH IDIOPATHIC ISOLATED GROWTH HORMONE DEFICIENCY

Big data as a strategy in the development of population auxological studies

PREDICT – A randomized investigation of a reduced prenatal dexamethasone dose to reduce virilization in female fetuses with congenital adrenal hyperplasia

A Novel Peroxisomal Cause of Primary Adrenal İnsufficiency: Pseudo-neonatal Adrenoleukodystrophy Due to ACOX1 Mutations.

Multi-hit Model of Primary Adrenal Insufficiency in CPOX mutations

Rare Genetic Etiology of Primary Adrenal Insufficiency in Children; Clinical and Genetic Characterization Of a Large Sudanese Cohort

Mitochondrial Nicotinamide Nucleotide Transidrogenase (NNT) and NNT-AS1 impairment is associated with worse outcomes in patients with adrenocortical tumors

Prospective evaluation of urinary outcome after partial urogenital sinus mobilization (PUM) for toilet trained female patients with classic congenital adrenal hyperplasia (CAH).

Prenatal Steroid profiling in 46,XY Disorders of sexual Development (DSD) : A 10 year Retrospective Cohort study

Effects of the modified release hydrocortisone preparation Efmody® on hormones, spermatogenesis and body weight in males with congenital adrenal hyperplasia

Nanoencapsulated Curcumin-Piperine Complex: A Breakthrough in Targeting CYP17A1 for Managing Androgen Excess in Adolescents with PCOS.

Testicular function in prepubertal boys with haematological malignancies during and post chemotherapy: a prospective, longitudinal study

Reevaluating Guidelines for Primary Ovarian Insufficiency Workup: Is It Time for a Change?

GnRHa TREATMENT OF CRYPTORCHIDISM ALTERS TESTICULAR SUMO GENE EXPRESSION

Long-Term Endocrine Outcomes of Acute Lymphoblastic Leukemia Treatment with Special Emphasis on the Gonadal Impact

Ten-year follow up for Children with non-lethal form of Raine Syndrome: Single Center Experience in Oman

Anthropometric changes in survivors of childhood acute lymphoblastic leukemia treated on the Italian Association of Pediatric Hematology and Oncology protocols without radiotherapy in the last two decades: preliminary data from an Italian tertiary center.

Manifestation of PTEN and MUTYH gene mutations: A Case Report

GAD-65 antibody positive autoimmune encephalitis with type III autoimmune polyendocrine syndrome: a rare pediatric case report

Different Faces of Carney Complex: Report of Three Cases

Corneal Nerve Loss and regeneration after GLP-1 Therapy in Children with Simple and Monogenic Obesity

Frequency of Bardet-Biedl syndrome variants in a population with early-onset obesity

SPISE is more strongly correlated with cardiometabolic factors in adolescents with obesity than HOMA-IR, and is related to the amount of body weight reduction under lifestyle intervention

Relaxation of Food Control Parameters Based on Improvements in the Food Safe Zone Questionnaire Occurs with Reduction of Hyperphagia in Clinical Trials of Diazoxide Choline Extended Release (DCCR) in Participants with Prader-Willi Syndrome

FIRST CROSS SECTIONAL ANALYSIS OF THE ECLIP REGISTRY

Novel Melanocortin and Gut-peptide Dual Agonist for Obesity and Diabetes Treatment

Clinical characteristics and response to growth hormone treatment in 27 children and adolescents with pathogenic NPR2 variants

Stratifying genetic etiology in children born small for gestational age with persistent short stature (SGA-SS): 5-year growth hormone (GH) treatment outcomes in genetic subgroups

Growth hormone (GH) deficiency and subsequent replacement therapy trigger differential expression of specific miRNAs in males and females: not just a matter of height

Growth Hormone Response to Glucagon Stimulation Test in Transitional Age

Use of overnight GH sampling in the diagnosis of growth disorders in children: neuroimaging findings and response to treatment

Growth, IGF-1 and IGFBP-3 Responses to Oral LUM-201 in OraGrowtH210 and OraGrowtH212 Trials in Pediatric Growth Hormone Deficiency (PGHD) over 12 to 24 Months on Treatment

Quantitative proteomics of pediatric adrenocortical tumors provides insights into zone of origin and identifies overrepresented pathways

Detection and differentiation of adrenocortical tumors (ACTs) in children by gas chromatography-mass spectrometry (GC-MS) based urinary steroid metabotyping

Insight into the role of TXNRD2 in steroidogenesis through a novel homozygous TXNRD2 splice variant

A deep intronic splice variant of CYP11B1 is the most common in Caucasian patients with 11-beta hydroxylase deficiency: functional, clinical and hormonal findings in 36 families

Free cortisol and free 21-deoxycortisol in the clinical evaluation of adrenal insufficiency in congenital adrenal hyperplasia

Plasma concentrations of renin and ACTH in children and adolescents from the general population: new reference intervals according to sex, age, and pubertal stage

A tiered approach to exome sequencing analysis in early-onset Primary Ovarian Insufficiency

Unveiling DHT-driven Androgen Receptor target genes in genital skin fibroblasts

Prenatal exposure to paracetamol is associated with reduced uterine volume at infancy - A COPANA Cohort study of 302 healthy girls

Prenatal exposure to paracetamol is associated with smaller testis volume and decreased levels of steroid metabolites during infancy in healthy males: A COPANA cohort study of 287 boys

Sex hormones shape the skeleton: The impact of puberty suppression and gender affirming hormone therapy on skeletal dimensions in transgender individuals

The Gender Identity Questionnaire for Children: a useful tool for gender identity detection in early life

Genetic screening and tumour surveillance program outcomes in rare paediatric hereditary endocrine tumour syndromes

Characterising the natural history of Multiple Endocrine Neoplasia 2B caused by M918TRET pathogenic variants in children and young people

Endocrine disorders in a wide cohort of children and adolescents affected by Neurofibromatosis type 1

A novel de novo SAMD9 gene variant causing MIRAGE syndrome associated with steroid-resistant nephrotic syndrome in a 46,XY male.

Using sno-lncRNAs as potential markers for Prader-Willi syndrome diagnosis

Comprehensive analysis of disease spectrum and mortality in Sanjad-Sakati Syndrome: A Rare Disease Perspective

The importance of chronobiology for medicine – when time matters

ESPE International Outstanding Clinician Award

Outstanding Clinician Award

ESPE Hormone Research in Paediatrics Prizes

IFCAH-ESPE Award

Introduction

Future of Registers for Rare Disease: the example E-REC

Genetic testing in rare forms of primary adrenal insufficiency

The patient perspective on new treatment options (example hypogonadotropic hypogonadism)

Innovations in pharmacotherapy of CAH

Translational Clinical Applications of Complex Steroidobolome Data

Lessons from CAH service evaluation and real world data

Molecular Basis of Congenital Hypopituitarism

New insights into Gonadotrope development

Management of pituitary stalk thickening in children and young people

Stem cells in skeletal development and growth

Genetic disorders of bone - historic perspectives and novel advances

Consensus statement on management of achondroplasia

Pharmacotherapy of Obesity

Impact of adolescent obesity on adult morbidity and mortality

Bariatic surgery: impact beyond weight

Antenatal and Neonatal Endocrinology

Oncology and Chronic Disease

Type 1 Diabetes

Obesity and Weight Regulation

The Year in Science & Medicine

MKRN3 and the initiation of puberty

Pharmacological treatment options for adolescents with Obesity

Closed loop in the very young

Managing difficult menstrual periods

The Diagnosis & Management of Rickets in the 21st Century

Bone, Growth Plate and Mineral Metabolism

DSD and gender incongruence

Thyroid

Pituitary and Neuroendocrinology

Editors' Choice

How do I...Manage Fertility Preservation in Young People with Klinefelter syndrome?

How do I...Manage a child with Hypopituitarism

How do I...Diagnose and manage pre-diabetes

Assessing how the Edmonton Obesity Staging System for Pediatrics (EOSS-P) in childhood relates to later cardiometabolic health compared to other anthropometric measures of obesity

Is the Single Point Insulin Sensitivity Estimator (SPISE) index a reliable tool for children and adolescents with overweight/obesity?

Ultrasound evaluation of kidney and liver involvement in Bardet-Biedl syndrome

Association of whole blood amino acid and acylcarnitine metabolome with anthropometry and IGF1 serum levels in healthy children and adolescents

Hepatic lipogenesis increases FGF21 in children/adolescents with obesity.

Pten knockout in osteoprogenitor cells leads to loss of adipose tissue

From neurology to endocrine: Misdiagnosed MCT8 deficiency

Prevalence and etiology of thyroid disorders and Characteristic of thyroid function tests in preterm infants

Mechanisms and natural history of pituitary resistance to exogenous thyroxine in children with congenital hypothyroidism

Establishing Outcomes and Management of Mild Neonatal Hyperthyrotropinaemia, a Retrospective Multi-Centre Review

Use of the FT3/FT4 ratio as a predictor of relapse in autoimmune hyperthyroidism: retrospective study on a cohort of 80 pediatric patients

Evaluation of thyroid nodules in children and adolescents by shear wave elastography (SWE)

MRI-based radiomics of the pituitary gland is highly predictive of CentralPrecocious Puberty in girls: pilot study

Novel anatomical quantification of all hypothalamic, pituitary, and stalk components predicts the severity of neuroendocrine phenotypes.

Unstimulated copeptin and oxytocin concentrations correlate with hypothalamic volumes and posterior pituitary location in congenital and acquired salt-water imbalance disorders.

Investigation of Pituitary Function in Langerhans Cell Histiocytosis: A Comprehensive Analysis of Clinical and Radiological Findings

The Development and Validation of Bone-age guided Interpretation of Puberty, a web-based tool for guidance of pubertal disorders

Hypogonadism hyperprolactinemia-related and its treatment in three patients with inherited disorders of biogenic amine metabolism

The LIFE-MILCH project: preliminary data from the risk assessment model of exposure to Endocrine Disrupting Chemicals (EDCs) in mother-infant dyads during the first 3 months of life.

Does gestational diabetes mellitus influence mitochondrial dynamics in offspring?

Complex Glycerol Kinase Deficiency: four new cases and a review of the literature

Neurodevelopmental response to nifedipine treatment in an infant with Congenital Hyperinsulinism due to de novo gain-of-function CACNA1D variant.

The utility of ketones in screening for congenital hyperinsulinism: a retrospective evaluation.

Utility of Continuous Glucose Monitoring in hospital monitoring of patients with Hyperinsulinism

Altered expression of epigenetic regulators is associated with high infertility risk in patients diagnosed with cryptorchidism.

Study on effects of poly- and perfluoroalkyl substances on hormones in girls with central precocious puberty

The different faces of acquired hypothalamic dysfunction.

Autoimmunity in children with type 1 diabetes in association with the COVID_19 pandemic - results from the prospective DPV Registry

Prevalence and management of modifiable cardiovascular risk factors among adolescents and young adults with type 1 diabetes – a cross-sectional analysis from the Diabetes Prospective Follow-Up Registry DPV

Macrophage switch and iron metabolism regulation by Burosumab in XLH pediatric patients: implications in inflammation and pain modulation.

Frequency of rare syndromic diseases in a population with early-onset obesity

Frequency of rare non-syndromic diseases in a population with early-onset obesity

Asprosin serum levels in subjects with Prader-Willi Syndrome: associations with hyperphagia, anthropometric, and metabolic parameters

Long-term Efficacy Results of Diazoxide Choline Extended-Release (DCCR) Tablets in Participants with Prader-Willi Syndrome from the Completed C601 (DESTINY PWS) and C602 Open Label Extension (OLE) Studies

Complement 3 Alleviates Obesity Hypoventilation by Inhibiting Caspase-8/GSDME-Related Pyroptosis

Poly- and Perfluoroalkyl substances (PFAS) levels and breastfeeding have opposite associations with growth and body composition at age 3 years

Use of targeted Next-Generation Sequencing panel in patients with non-autoimmune hypothyroidism: the experience of an Italian Pediatric Endocrinology Center

Molecular Characterization of Childhood Thyroid Nodules and Thyroid Cancer with DNA/RNA Next Generation Sequencing and Investigation of Phenotype-Genotype Correlation

Usefulness of application novel TurboTM TSAb bioassay in the monitoring of pediatric Graves’ patients

Docosahexaenoic acid (DHA) is reduced and could be protective against Hashimoto’s thyroiditis in children with Down syndrome: a cross-sectional study

The Association between Plasma Thyroxine Levels and Attention-Deficit/Hyperactivity Disorder

The First Robust Bioavailability/Bioequivalence (BA/BE) Study of Thyromimetic Tiratricol, a Treatment in Development for MCT8 Deficiency.

Defect in C-terminal alpha-amidation during Kisspeptin synthesis: a new mechanism of hypogonadotropic hypogonadism

Copy Number Variation (CNV) in Self-limited Delayed Puberty (SLDP)

Effect of Precocious Puberty and GnRHa Treatment on Glucose Metabolism in Female Rats

Relationship between the timing of the physical changes of puberty and total pubertal growth in healthy adolescents: new insights which can provide helpful clinical guidance

Rising in body mass index during childhood in girls with idiopathic CPP : a 20-year experience in a tertiary Belgian centre.

Voice frequency in healthy children and adolescents: A biomarker of androgen action in puberty

Non-invasive prenatal testing can detect maternally and paternally inherited variants in the KCNJ11 and ABCC8 genes: implications for clinical management of neonatal diabetes during pregnancy and beyond

Cord glucose: A normal reference and a potential of an ideal universal screening tool for pathological hyperinsulinism.

Reduction of Overnight Hypoglycemia in Congenital Hyperinsulinism: Results from the RZ358-606 (RIZE) Study

Efficacy and Safety across Subgroups in Children with Congenital Hyperinsulinism Treated with Dasiglucagon

A novel 94bp deletion in the SLC16A1 promoter causes fasting and exercise-induced hyperinsulinaemic hypoglycaemia

Patient and Carer Perspectives: A National Survey of Continuous Glucose Monitoring in Children with Congenital Hyperinsulinism in the UK