Days At A Glance Speakers Session Type Search
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    12:00 - 19:30 
    Registration
    14:00 - 17:00 
    Training course: Bone – Bedside to Bench and Back
    Chairs: Coen Netelenbos (Amsterdam, Netherlands) & Craig B Langman (Chicago, USA)
    Training course: Bone – Bedside to Bench and Back
    What does a basic bone scientist need to know about clinical bone disease in children?
    Sheffield, UK
    Training course: Bone – Bedside to Bench and Back
    What does a clinical bone scientist need to know about basic bone biology?
    (Boston, USA)
    15:00 - 17:00 
    Approaches to: Hypogonadal bone diseases & Phosphate metabolism and bone diseases
    15:00 - 16:00 
    Hypogonadal bone diseases
    Convenor: Coen Netelenbos
    Speakers: Wolfgang Högler & Annemieke Boot
    16:00 - 17:00 
    Phosphate metabolism and bone diseases
    Convenor: Craig B Langman
    Speakers: Rachel Gafni & Farzana Perwad
    17:00 - 17:15 
    Break
    17:15 - 17:30 
    Welcome
    Maria Luisa Bianchi (Milan, Italy) Sabine de Muinck Keizer-Schrama (Rotterdam, Netherlands)
    17:30 - 18:00 
    Keynote Lecture: The past, the present and the future of pediatric bone research
    Chair: Maria Luisa Bianchi (Milan, Italy)
    Speaker: Francis Glorieux (Montreal, Canada)
    18:00 - 19:00 
    Welcome Reception
    WILLEM BURGER ZAAL FOYER

    08:00 - 19:00 
    Registration
    08:30 - 10:30 
    The Fracturing Child: Epidemiology
    Chairs: Catherine Gordon (Boston, USA) & Zulf Mughal (Manchester, UK)
    IS1
    The Fracturing Child: Epidemiology
    Bone mass and other determinants of fractures in children and adolescents
    (Bristol, UK)
    IS2
    The Fracturing Child: Epidemiology
    Epigenetic influences on childhood fractures
    Oxford, UK
    09:30 - 10:30 
    Oral Communications: Epidemiology
    OC1
    Oral Communications: Epidemiology
    The Amalgamated Paediatric Bone Density Study (The ALPHABET Study) - The collation and generation of UK based reference data for paediatric bone densitometry
    Birmingham, UK
    OC2
    Oral Communications: Epidemiology
    Fracture patterns and bone mass in South African adolescent-mother pairs: The Birth to Twenty Cohort
    (Johannesburg, South Africa)
    OC3
    Oral Communications: Epidemiology
    Pediatric differences in Bone Mineral Density according to ethnic background in children: the Generation R Study
    Rotterdam, Netherlands
    OC4
    Oral Communications: Epidemiology
    Maternal antenatal 25(OH)-vitamin D status is associated with offspring muscle strength at 4 years of age
    Southampton, UK
    OC5
    Oral Communications: Epidemiology
    Novel musculoskeletal phenotypes during childhood for epidemiological studies
    Oxford, UK
    OC6
    Oral Communications: Epidemiology
    Role of bone-associated loci identified in GWAS meta-analyses in the context of longitudinal pediatric BMD in European Americans
    (Philadelphia, USA)
    10:30 - 10:35 
    Charles Slemenda Award
    10:35 - 11:00 
    Coffee
    11:00 - 13:00 
    The Fracturing Child: Biology
    Chairs: Rachel Gafni (Bethesda, USA) & Gerard Pals (Amsterdam, Netherlands)
    IS3
    The Fracturing Child: Biology
    Bone structure and fractures
    Rochester, USA
    IS4
    The Fracturing Child: Biology
    The biology of bone revealed through bone biopsy
    Los Angeles, USA
    12:00 - 13:00 
    Oral Communications: Biology
    OC7
    Oral Communications: Biology
    The PPP6R3/LRP5 locus influences lean mass in children of different ethnic background and highlights pleiotropic effects and muscle-bone interactions
    Rotterdam, Netherlands
    OC8
    Oral Communications: Biology
    Generation of the first mouse model of Autosomal Dominant Type II Osteopetrosis ADO2) harbouring the pG213R-clc7 mutation
    Rome, Italy
    OC9
    Oral Communications: Biology
    EPO signaling and hematopoietic expansion as causes of osteoporosis in a thalassemia mouse model
    New York, USA
    OC10
    Oral Communications: Biology
    Phenotypic dissection of bone mineral density facilitates the identification of skeletal site specificity on the genetic regulation of bone
    (Bristol, UK)
    OC11
    Oral Communications: Biology
    Connectivity map-based discovery of novel compounds that induce osteoblast differentiation
    Rotterdam, The Netherlands
    OC12
    Oral Communications: Biology
    Improvement of collagen synthesis in fibroblasts of Brtl model for Osteogenesis Imperfecta following lentiviral-shRNA-mediated down-expression of mutant Col1a1 allele
    Nantes, France
    13:00 - 13:30 
    Lunch
    13:30 - 14:30 
    Posters (odd numbers presented)
    14:30 - 15:45 
    Oral Posters
    Chairs: Nick Bishop (Sheffield, UK) & Coen Netelenbos (Amsterdam, Netherlands)
    OP1
    Oral Posters
    Skeletal effects of hypothyroidism are mediated by thyroid hormone receptor
    London, UK
    OP2
    Oral Posters
    High FSH serum levels may support the altered bone remodeling in Turner Syndrome patients
    Bari, Italy
    OP3
    Oral Posters
    Calcimimetics as adjunct therapy in XLH: 18 months experience
    Kansas City, USA
    OP4
    Oral Posters
    A new start-codon in IFITM5 causes Osteogenesis Imperfecta Type V
    Cologne, Germany
    OP5
    Oral Posters
    Abstract withdrawn
    OP6
    Oral Posters
    Children with nephrotic syndrome have increased tibial bone area but similar volumetric bone mineral density to healthy controls
    Southampton, UK
    OP7
    Oral Posters
    Bone Mineralization Density Distribution, bone formation rate and bone turnover markers in a cohort of children with CKD before and after growth hormone treatment
    Vienna, Austria
    OP8
    Oral Posters
    Quantitative measurement of abnormal bone quality and strength with bone microarchitecture and rod-plate configuration in osteopenic adolescent idiopathic scoliosis (AIS)
    Hong Kong, China
    15:10 - 15:45 
    Oral Posters
    Chairs: Nick Bishop (Sheffield, UK) & Coen Netelenbos (Amsterdam, Netherlands)
    OP9
    Oral Posters
    Anticalciuric effect of recombinant PTH in patients with activating mutations of the calcium-sensing receptor causing autosomal dominant hypocalcaemia-hypercalciuria (ADHH)
    Paris, France
    OP10
    Oral Posters
    Metacarpal width, length, medullary diameter and cortical thickness in hypophosphatemic rickets
    Esbjerg, Denmark
    OP11
    Oral Posters
    Artistic gymnasts display micro-architectural advantages over trampolining and tumbling gymnasts: A high resolution peripheral quantitative computed tomography study
    Calgary, Canada
    OP12
    Oral Posters
    The bone/vessels interplay in teenagers with chronic kidney disease
    Lyons, France
    OP13
    Oral Posters
    Long-term effects of bisphosphonate therapy in children with osteogenesis imperfecta
    Sydney, Australia
    OP14
    Oral Posters
    Inflammation and glucocorticoid therapy impair skeletal modeling during growth following Crohn Disease diagnosis
    (Philadelphia, USA)
    OP15
    Oral Posters
    Dissecting the role of osteoblast derived nitric oxide in bone remodeling
    Houston, USA
    15:45 - 16:15 
    Coffee
    16:15 - 17:45 
    Rare diseases
    Chairs: Paul Baldock (Sydney, Australia) & Frank Rauch (Montreal, Canada)
    IS5
    Rare diseases
    Acrodysostosis
    Paris, France
    IS6
    Rare diseases
    Gaucher
    Genoa, Italy
    IS7
    Rare diseases
    Osteogenesis Imperfecta
    Amsterdam, Netherlands
    17:45 - 18:00 
    Break
    18:00 - 21:00 
    Dinner Symposium: Differentiating unusual causes of rickets and hypercalcemia
    Supported by: Alexion Pharmaceuticals
    18:00 - 20:00 
    Scientific presentations
    WILLEM BURGER AUDITORIUM (3RD FLOOR)
    Scientific presentations
    Welcome/Introduction/Case Introduction
    Chicago, USA
    Scientific presentations
    New insights on vitamin D metabolism: the role of 24-hydroxylase
    Münster, Germany
    Scientific presentations
    Hormone independent hypercalcemia: Jansen’s metaphyseal chondrodysplasia
    (Boston, USA)
    Scientific presentations
    Hypophosphatasia: the impact of alkaline phosphatase deficiency
    Sheffield, UK
    Scientific presentations
    Case Discussion: pathogenesis and differential diagnosis
    20:00 - 21:00 
    Dinner
    ARCADIS ZAAL (1ST FLOOR)

    08:00 - 19:00 
    Registration
    08:30 - 10:30 
    The Fracturing Child: Diagnostics
    Chairs: Paul Dimitri (Sheffield, UK) & Craig Munns (Sydney, Australia)
    IS8
    The Fracturing Child: Diagnostics
    Non-invasive assessment of bone structure and strength using QCT and MRI
    (Philadelphia, USA)
    IS9
    The Fracturing Child: Diagnostics
    DXA and Vertebral Fracture Assessment
    Manchester, UK
    09:30 - 10:30 
    Oral Communications: Diagnostics
    OC13
    Oral Communications: Diagnostics
    Level of calcium intake modifies the correlation between parathyroid hormone and 25-hydroxyvitamin D: A proposal of adequate 25-hydroxyvitamin D levels in children
    Santiago, Chile
    OC14
    Oral Communications: Diagnostics
    What DXA measurement sites are best for bone health assessment in children? Effect of inter-machine differences on bone outcomes from the Bone Mineral Density in Childhood Study (BMDCS)
    (Philadelphia, USA)
    OC15
    Oral Communications: Diagnostics
    Bone Health Index: Swiss children have less in the bank than a generation ago
    Hørsholm, Denmark
    OC16
    Oral Communications: Diagnostics
    Longitudinal analysis of volumetric density, size and strength towards the end of skeletal maturation in Gambian males habituated to low calcium intake
    (Cambridge, UK)
    OC17
    Oral Communications: Diagnostics
    Determinants of bone mineral density in long-term adult survivors of childhood cancer
    Rotterdam, Netherlands
    OC18
    Oral Communications: Diagnostics
    Trabecular bone score (TBS) applied to normal children's lumbar spine DXA scans
    Manchester, UK
    10:30 - 11:00 
    Coffee
    11:00 - 13:00 
    The Fracturing Child: Therapeutics
    Chairs: Francis Glorieux (Montreal, Canada) & Farzana Perwad (San Francisco, USA)
    IS10
    The Fracturing Child: Therapeutics
    Medical therapies: present and future
    Brisbane, Australia
    IS11
    The Fracturing Child: Therapeutics
    Other therapeutic options: nutrition, vitamin D, physical activity
    Boston, USA
    12:00 - 13:00 
    Oral Communications: Miscellaneous
    OC19
    Oral Communications: Miscellaneous
    New therapeutic approach in OI VI - suppression of bone resorption using the RANKL antibody denosumab
    Cologne, Germany
    OC20
    Oral Communications: Miscellaneous
    Exercise completed when young provides lifelong benefit to cortical bone structure and estimated strength
    Indianapolis, USA
    OC21
    Oral Communications: Miscellaneous
    A randomized, double-blind, placebo-controlled trial of alendronate treatment for fibrous dysplasia of bone
    Bethesda, USA
    OC22
    Oral Communications: Miscellaneous
    Prolidase deficient mice are osteoporotic in early life
    Sheffield, UK
    OC23
    Oral Communications: Miscellaneous
    Switching from alendronate to RANKL blockade alters bone properties after 14 weeks of therapy in the oim/oim mouse
    New York, USA
    OC24
    Oral Communications: Miscellaneous
    Fibroblast growth factor 23 plasma levels are elevated with early chronic kidney disease and positively associated with steroid based versus steroid free immunosuppression in pediatric renal transplant patients
    Houston, USA
    13:00 - 13:30 
    Lunch
    13:30 - 14:30 
    Posters (even numbers presented)
    14:30 - 15:30 
    Chronic diseases
    Chairs: Wolfgang Högler (Birmingham, UK) & Carmen Wilson (Memphis, USA)
    IS12
    Chronic diseases
    IBD, bone, fractures and inflammation
    Gothenburg, Sweden
    IS13
    Chronic diseases
    Muscle-bone interaction in pediatric bone diseases
    Montreal, Canada
    15:30 - 16:00 
    Coffee
    16:00 - 17:30 
    Chronic diseases
    Chairs: Mary Leonard (Philadelphia, USA) & Agnès Linglart (Paris, France)
    16:00 - 17:00 
    Oral Communications: Chronic diseases
    OC25
    Oral Communications: Chronic diseases
    Wnt/ ß-catenin: A candidate pathway for bone repair in Neurofibromatosis Type-1
    Toronto, Canada
    OC26
    Oral Communications: Chronic diseases
    Vertebral fractures in the 3 year period following steroid initiation among children with chronic illnesses
    Calgary, Canada
    OC27
    Oral Communications: Chronic diseases
    Serum vitamin D level can affect the treatment outcome of whole-body vibration (WBV) for low bone mass in girls with Adolescent Idiopathic Scoliosis (AIS)
    Hong Kong, Hong Kong
    OC28
    Oral Communications: Chronic diseases
    Bone mineral density at diagnosis determines fracture rate in children treated according to the DCOG-ALL9 protocol.
    Rotterdam, Netherlands
    OC29
    Oral Communications: Chronic diseases
    Mineral metabolism, cortical volumetric bone mineral density and fracture risk in childhood chronic kidney disease
    Philadelphia, USA
    OC30
    Oral Communications: Chronic diseases
    Alteration of Wnt/Beta-Catenin signaling in HIV-infected youths: A mechanism leading to impaired bone health?
    Milan, Italy
    IS14
    Oral Communications: Chronic diseases
    Type I Diabetes
    Munich, Germany
    17:30 - 19:00 
    Satellite Symposium: Vitamin D: Shifting the Status
    Supported by: Danone Baby Nutrition
    Chair: Nick Bishop (Sheffield, UK)
    Satellite Symposium: Vitamin D: Shifting the Status
    Global burden of vitamin D deficiency
    Dubai , UAE
    Satellite Symposium: Vitamin D: Shifting the Status
    Food based strategies for increasing vitamin D status in young children
    Cork, Ireland
    Satellite Symposium: Vitamin D: Shifting the Status
    Vitamin D deficiency in adolescence
    Boston, USA
    Satellite Symposium: Vitamin D: Shifting the Status
    Buses depart for Conference Party from Conference Centre entrance immediately following Satellite Symposium
    19:30 - 23:00 
    Conference Party
    Buses return to the Conference Centre from 22:30, calling at the Hilton, Manhattan and Bilderberg hotels. It is a short walk from the disembarkation point to the Inntel, Maritime and StayOK hotels
    Supported by: DANONE BABY NUTRITION
    Location: PADDLESTEAMER DE MAJESTEIT

    08:30 - 08:40 
    Presentation of Awards
    Chairs: Maria Luisa Bianchi (Milan, Italy) & Coen Netelenbos (Amsterdam, Netherlands)
    08:40 - 09:00 
    Late Breaking Abstracts
    Chairs: Nick Bishop (Sheffield, UK) & Craig B Langman (Chicago, USA)
    LB1
    Late Breaking Abstracts
    Influence of age and gender on spine bone density and TBS microarchitectural texture parameters in infants
    Pessac, France
    LB2
    Late Breaking Abstracts
    WNT1 mutations in early-onset osteoporosis and osteogenesis imperfecta identify a key WNT ligand regulating bone mass
    Helsinki, Finland
    09:00 - 10:20 
    Paediatric cancer and bone: Round Table
    Chairs: Sabine de Muinck Keizer-Schrama (Rotterdam, Netherlands) & Roman Lorenc (Warsaw, Poland)
    IS15
    Paediatric cancer and bone: Round Table
    Bone and endocrine side-effects in childhood Hodgkins lymphoma and acute lymphoblastic leukemia
    Rotterdam, Netherlands
    IS16
    Paediatric cancer and bone: Round Table
    Childhood cancer and fractures
    Memphis, USA
    Paediatric cancer and bone: Round Table
    Round Table discussion
    10:20 - 10:45 
    Coffee
    10:45 - 12:05 
    Obesity as a bone disease: Round Table
    Chairs: Aenor Sawyer (San Francisco, USA) & Eckhard Schönau (Cologne, Germany)
    IS17
    Obesity as a bone disease: Round Table
    Bone as an endocrine organ
    IS18
    Obesity as a bone disease: Round Table
    Obesity and skeletal health
    Sheffield, UK
    Obesity as a bone disease: Round Table
    Round Table discussion
    12:05 -  
    Closing Remarks
Judith Adams
Manchester, UK
Mon 24 09:00
IS9
The Fracturing Child: Diagnostics
DXA and Vertebral Fracture Assessment
Manchester, UK
Mon 24 10:20
OC18
Oral Communications: Diagnostics
Trabecular bone score (TBS) applied to normal children's lumbar spine DXA scans
Manchester, UK
Uri Alon
Kansas City, USA
Sun 23 14:40
OP3
Oral Posters
Calcimimetics as adjunct therapy in XLH: 18 months experience
Kansas City, USA
Justine Bacchetta
Lyons, France
Sun 23 15:25
OP12
Oral Posters
The bone/vessels interplay in teenagers with chronic kidney disease
Lyons, France
Paul Baldock
Tue 25 10:45
IS17
Obesity as a bone disease: Round Table
Bone as an endocrine organ
Rajbir Batra
Oxford, UK
Sun 23 10:10
OC5
Oral Communications: Epidemiology
Novel musculoskeletal phenotypes during childhood for epidemiological studies
Oxford, UK
Susanne Bechtold
Munich, Germany
Mon 24 17:00
IS14
Oral Communications: Chronic diseases
Type I Diabetes
Munich, Germany
Signe Beck-Nielsen
Esbjerg, Denmark
Sun 23 15:15
OP10
Oral Posters
Metacarpal width, length, medullary diameter and cortical thickness in hypophosphatemic rickets
Esbjerg, Denmark
Andrew Biggin
Sydney, Australia
Sun 23 15:30
OP13
Oral Posters
Long-term effects of bisphosphonate therapy in children with osteogenesis imperfecta
Sydney, Australia
Nick Bishop
Sheffield, UK
Sat 22 14:00
Training course: Bone – Bedside to Bench and Back
What does a basic bone scientist need to know about clinical bone disease in children?
Sheffield, UK
Sun 23
Scientific presentations
Hypophosphatasia: the impact of alkaline phosphatase deficiency
Sheffield, UK
Alison Boyce
Bethesda, USA
Mon 24 12:20
OC21
Oral Communications: Miscellaneous
A randomized, double-blind, placebo-controlled trial of alendronate treatment for fibrous dysplasia of bone
Bethesda, USA
Andrea Brum
Rotterdam, The Netherlands
Sun 23 12:40
OC11
Oral Communications: Biology
Connectivity map-based discovery of novel compounds that induce osteoblast differentiation
Rotterdam, The Netherlands
Giacomina Brunetti
Bari, Italy
Sun 23 14:35
OP2
Oral Posters
High FSH serum levels may support the altered bone remodeling in Turner Syndrome patients
Bari, Italy
Lauren Burt
Calgary, Canada
Sun 23 15:20
OP11
Oral Posters
Artistic gymnasts display micro-architectural advantages over trampolining and tumbling gymnasts: A high resolution peripheral quantitative computed tomography study
Calgary, Canada
Moira Cheung
London, UK
Sun 23 14:30
OP1
Oral Posters
Skeletal effects of hypothyroidism are mediated by thyroid hormone receptor
London, UK
Emma Clark
(Bristol, UK)
Sun 23 08:30
IS1
The Fracturing Child: Epidemiology
Bone mass and other determinants of fractures in children and adolescents
(Bristol, UK)
Nicola Crabtree
Birmingham, UK
Sun 23 09:30
OC1
Oral Communications: Epidemiology
The Amalgamated Paediatric Bone Density Study (The ALPHABET Study) - The collation and generation of UK based reference data for paediatric bone densitometry
Birmingham, UK
Michelle Denburg
Philadelphia, USA
Mon 24 16:40
OC29
Oral Communications: Chronic diseases
Mineral metabolism, cortical volumetric bone mineral density and fracture risk in childhood chronic kidney disease
Philadelphia, USA
Professor  Paul Dimitri
Sheffield, UK
Tue 25 11:15
IS18
Obesity as a bone disease: Round Table
Obesity and skeletal health
Sheffield, UK
Andrea Fattore
Rome, Italy
Sun 23 12:10
OC8
Oral Communications: Biology
Generation of the first mouse model of Autosomal Dominant Type II Osteopetrosis ADO2) harbouring the pG213R-clc7 mutation
Rome, Italy
Sarah Foster
Sheffield, UK
Mon 24 12:30
OC22
Oral Communications: Miscellaneous
Prolidase deficient mice are osteoporotic in early life
Sheffield, UK
Nadja Fratzl-Zelman
Vienna, Austria
Sun 23 15:00
OP7
Oral Posters
Bone Mineralization Density Distribution, bone formation rate and bone turnover markers in a cohort of children with CKD before and after growth hormone treatment
Vienna, Austria
Saber Ghadakzadeh
Toronto, Canada
Mon 24 16:00
OC25
Oral Communications: Chronic diseases
Wnt/ ß-catenin: A candidate pathway for bone repair in Neurofibromatosis Type-1
Toronto, Canada
Carolina Gomez
Rotterdam, Netherlands
Sun 23 09:50
OC3
Oral Communications: Epidemiology
Pediatric differences in Bone Mineral Density according to ethnic background in children: the Generation R Study
Rotterdam, Netherlands
Catherine Gordon
Boston, USA
Mon 24 11:30
IS11
The Fracturing Child: Therapeutics
Other therapeutic options: nutrition, vitamin D, physical activity
Boston, USA
Mon 24
Satellite Symposium: Vitamin D: Shifting the Status
Vitamin D deficiency in adolescence
Boston, USA
Monica Grover
Houston, USA
Sun 23 15:40
OP15
Oral Posters
Dissecting the role of osteoblast derived nitric oxide in bone remodeling
Houston, USA
Marry Heuvel-Eibrink
Rotterdam, Netherlands
Tue 25 09:00
IS15
Paediatric cancer and bone: Round Table
Bone and endocrine side-effects in childhood Hodgkins lymphoma and acute lymphoblastic leukemia
Rotterdam, Netherlands
Heike Hoyer-Kuhn
Cologne, Germany
Mon 24 12:00
OC19
Oral Communications: Miscellaneous
New therapeutic approach in OI VI - suppression of bone resorption using the RANKL antibody denosumab
Cologne, Germany
Professsor  Kassim	 Javaid
Oxford, UK
Sun 23 09:00
IS2
The Fracturing Child: Epidemiology
Epigenetic influences on childhood fractures
Oxford, UK
Harald Jüppner
(Boston, USA)
Sat 22 14:30
Training course: Bone – Bedside to Bench and Back
What does a clinical bone scientist need to know about basic bone biology?
(Boston, USA)
Sun 23
Scientific presentations
Hormone independent hypercalcemia: Jansen’s metaphyseal chondrodysplasia
(Boston, USA)
John Kemp
(Bristol, UK)
Sun 23 12:30
OC10
Oral Communications: Biology
Phenotypic dissection of bone mineral density facilitates the identification of skeletal site specificity on the genetic regulation of bone
(Bristol, UK)
Mairead Kiely
Cork, Ireland
Mon 24
Satellite Symposium: Vitamin D: Shifting the Status
Food based strategies for increasing vitamin D status in young children
Cork, Ireland
Salman Kirmani
Rochester, USA
Sun 23 11:00
IS3
The Fracturing Child: Biology
Bone structure and fractures
Rochester, USA
Martin Konrad
Münster, Germany
Sun 23
Scientific presentations
New insights on vitamin D metabolism: the role of 24-hydroxylase
Münster, Germany
Tsz Lam
Hong Kong, Hong Kong
Mon 24 16:20
OC27
Oral Communications: Chronic diseases
Serum vitamin D level can affect the treatment outcome of whole-body vibration (WBV) for low bone mass in girls with Adolescent Idiopathic Scoliosis (AIS)
Hong Kong, Hong Kong
Craig Langman
Chicago, USA
Sun 23
Scientific presentations
Welcome/Introduction/Case Introduction
Chicago, USA
Mary Leonard
(Philadelphia, USA)
Sun 23 15:35
OP14
Oral Posters
Inflammation and glucocorticoid therapy impair skeletal modeling during growth following Crohn Disease diagnosis
(Philadelphia, USA)
Mon 24 08:30
IS8
The Fracturing Child: Diagnostics
Non-invasive assessment of bone structure and strength using QCT and MRI
(Philadelphia, USA)
Agnès Linglart, MD, PhD
Paris, France
Sun 23 15:10
OP9
Oral Posters
Anticalciuric effect of recombinant PTH in patients with activating mutations of the calcium-sensing receptor causing autosomal dominant hypocalcaemia-hypercalciuria (ADHH)
Paris, France
Sun 23 16:15
IS5
Rare diseases
Acrodysostosis
Paris, France
Outi Mäkitie
Helsinki, Finland
Tue 25 08:50
LB2
Late Breaking Abstracts
WNT1 mutations in early-onset osteoporosis and osteogenesis imperfecta identify a key WNT ligand regulating bone mass
Helsinki, Finland
Carolina Medina-Gomez
Rotterdam, Netherlands
Sun 23 12:00
OC7
Oral Communications: Biology
The PPP6R3/LRP5 locus influences lean mass in children of different ethnic background and highlights pleiotropic effects and muscle-bone interactions
Rotterdam, Netherlands
Paivi Miettunen
Calgary, Canada
Mon 24 16:10
OC26
Oral Communications: Chronic diseases
Vertebral fractures in the 3 year period following steroid initiation among children with chronic illnesses
Calgary, Canada
Rebecca Moon
Southampton, UK
Sun 23 10:00
OC4
Oral Communications: Epidemiology
Maternal antenatal 25(OH)-vitamin D status is associated with offspring muscle strength at 4 years of age
Southampton, UK
Sun 23 14:55
OP6
Oral Posters
Children with nephrotic syndrome have increased tibial bone area but similar volumetric bone mineral density to healthy controls
Southampton, UK
Stefano Mora
Milan, Italy
Mon 24 16:50
OC30
Oral Communications: Chronic diseases
Alteration of Wnt/Beta-Catenin signaling in HIV-infected youths: A mechanism leading to impaired bone health?
Milan, Italy
Zulf Mughal
Dubai , UAE
Mon 24
Satellite Symposium: Vitamin D: Shifting the Status
Global burden of vitamin D deficiency
Dubai , UAE
Craig Munns
Brisbane, Australia
Mon 24 11:00
IS10
The Fracturing Child: Therapeutics
Medical therapies: present and future
Brisbane, Australia
Gerard Pals
Amsterdam, Netherlands
Sun 23 17:15
IS7
Rare diseases
Osteogenesis Imperfecta
Amsterdam, Netherlands
Saskia Pluijm
Rotterdam, Netherlands
Mon 24 10:10
OC17
Oral Communications: Diagnostics
Determinants of bone mineral density in long-term adult survivors of childhood cancer
Rotterdam, Netherlands
Cathleen Raggio
New York, USA
Mon 24 12:40
OC23
Oral Communications: Miscellaneous
Switching from alendronate to RANKL blockade alters bone properties after 14 weeks of therapy in the oim/oim mouse
New York, USA
Frank Rauch
Montreal, Canada
Mon 24 15:00
IS13
Chronic diseases
Muscle-bone interaction in pediatric bone diseases
Montreal, Canada
María Reyes
Santiago, Chile
Mon 24 09:30
OC13
Oral Communications: Diagnostics
Level of calcium intake modifies the correlation between parathyroid hormone and 25-hydroxyvitamin D: A proposal of adequate 25-hydroxyvitamin D levels in children
Santiago, Chile
Maja Rocco
Genoa, Italy
Sun 23 16:45
IS6
Rare diseases
Gaucher
Genoa, Italy
Susanne Schmidt
Gothenburg, Sweden
Mon 24 14:30
IS12
Chronic diseases
IBD, bone, fractures and inflammation
Gothenburg, Sweden
Simon Schoenbuchner
(Cambridge, UK)
Mon 24 10:00
OC16
Oral Communications: Diagnostics
Longitudinal analysis of volumetric density, size and strength towards the end of skeletal maturation in Gambian males habituated to low calcium intake
(Cambridge, UK)
Oliver Semler
Cologne, Germany
Sun 23 14:45
OP4
Oral Posters
A new start-codon in IFITM5 causes Osteogenesis Imperfecta Type V
Cologne, Germany
Rachana Srivastava
Houston, USA
Mon 24 12:50
OC24
Oral Communications: Miscellaneous
Fibroblast growth factor 23 plasma levels are elevated with early chronic kidney disease and positively associated with steroid based versus steroid free immunosuppression in pediatric renal transplant patients
Houston, USA
Kebashni Thandrayan
(Johannesburg, South Africa)
Sun 23 09:40
OC2
Oral Communications: Epidemiology
Fracture patterns and bone mass in South African adolescent-mother pairs: The Birth to Twenty Cohort
(Johannesburg, South Africa)
Hans Thodberg
Hørsholm, Denmark
Mon 24 09:50
OC15
Oral Communications: Diagnostics
Bone Health Index: Swiss children have less in the bank than a generation ago
Hørsholm, Denmark
Valérie Trichet
Nantes, France
Sun 23 12:50
OC12
Oral Communications: Biology
Improvement of collagen synthesis in fibroblasts of Brtl model for Osteogenesis Imperfecta following lentiviral-shRNA-mediated down-expression of mutant Col1a1 allele
Nantes, France
Maria Vogiatzi
New York, USA
Sun 23 12:20
OC9
Oral Communications: Biology
EPO signaling and hematopoietic expansion as causes of osteoporosis in a thalassemia mouse model
New York, USA
Stuart Warden
Indianapolis, USA
Mon 24 12:10
OC20
Oral Communications: Miscellaneous
Exercise completed when young provides lifelong benefit to cortical bone structure and estimated strength
Indianapolis, USA
Katherine Wesseling-Perry
Los Angeles, USA
Sun 23 11:30
IS4
The Fracturing Child: Biology
The biology of bone revealed through bone biopsy
Los Angeles, USA
Carmen Wilson
Memphis, USA
Tue 25 09:30
IS16
Paediatric cancer and bone: Round Table
Childhood cancer and fractures
Memphis, USA
Mariël Winkel
Rotterdam, Netherlands
Mon 24 16:30
OC28
Oral Communications: Chronic diseases
Bone mineral density at diagnosis determines fracture rate in children treated according to the DCOG-ALL9 protocol.
Rotterdam, Netherlands
Renaud Winzenrieth
Pessac, France
Tue 25 08:40
LB1
Late Breaking Abstracts
Influence of age and gender on spine bone density and TBS microarchitectural texture parameters in infants
Pessac, France
Wing Yu
Hong Kong, China
Sun 23 15:05
OP8
Oral Posters
Quantitative measurement of abnormal bone quality and strength with bone microarchitecture and rod-plate configuration in osteopenic adolescent idiopathic scoliosis (AIS)
Hong Kong, China
Babette Zemel
(Philadelphia, USA)
Sun 23 10:20
OC6
Oral Communications: Epidemiology
Role of bone-associated loci identified in GWAS meta-analyses in the context of longitudinal pediatric BMD in European Americans
(Philadelphia, USA)
Mon 24 09:40
OC14
Oral Communications: Diagnostics
What DXA measurement sites are best for bone health assessment in children? Effect of inter-machine differences on bone outcomes from the Bone Mineral Density in Childhood Study (BMDCS)
(Philadelphia, USA)
Workshop 0
Oral 0
Expert 0
Plenary 0
Catering and Social 0
Nurse 0
Other 0
Symposium 0
No Session Type 44
Sat 22 12:00
Registration
Sat 22 14:00
Training course: Bone – Bedside to Bench and Back
Chairs: Coen Netelenbos (Amsterdam, Netherlands) & Craig B Langman (Chicago, USA)
Sat 22 14:00
Training course: Bone – Bedside to Bench and Back
What does a basic bone scientist need to know about clinical bone disease in children?
Sheffield, UK
Sat 22 14:30
Training course: Bone – Bedside to Bench and Back
What does a clinical bone scientist need to know about basic bone biology?
(Boston, USA)
Sat 22 15:00
Approaches to: Hypogonadal bone diseases & Phosphate metabolism and bone diseases
Sat 22 15:00
Hypogonadal bone diseases
Convenor: Coen Netelenbos
Speakers: Wolfgang Högler & Annemieke Boot
Sat 22 16:00
Phosphate metabolism and bone diseases
Convenor: Craig B Langman
Speakers: Rachel Gafni & Farzana Perwad
Sat 22 17:00
Break
Sat 22 17:15
Welcome
Maria Luisa Bianchi (Milan, Italy) Sabine de Muinck Keizer-Schrama (Rotterdam, Netherlands)
Sat 22 17:30
Keynote Lecture: The past, the present and the future of pediatric bone research
Chair: Maria Luisa Bianchi (Milan, Italy)
Speaker: Francis Glorieux (Montreal, Canada)
Sat 22 18:00
Welcome Reception
WILLEM BURGER ZAAL FOYER
Sun 23 08:30
The Fracturing Child: Epidemiology
Chairs: Catherine Gordon (Boston, USA) & Zulf Mughal (Manchester, UK)
Sun 23 08:30
IS1
The Fracturing Child: Epidemiology
Bone mass and other determinants of fractures in children and adolescents
(Bristol, UK)
Sun 23 09:00
IS2
The Fracturing Child: Epidemiology
Epigenetic influences on childhood fractures
Oxford, UK
Sun 23 09:30
Oral Communications: Epidemiology
Sun 23 09:30
OC1
Oral Communications: Epidemiology
The Amalgamated Paediatric Bone Density Study (The ALPHABET Study) - The collation and generation of UK based reference data for paediatric bone densitometry
Birmingham, UK
Sun 23 09:40
OC2
Oral Communications: Epidemiology
Fracture patterns and bone mass in South African adolescent-mother pairs: The Birth to Twenty Cohort
(Johannesburg, South Africa)
Sun 23 09:50
OC3
Oral Communications: Epidemiology
Pediatric differences in Bone Mineral Density according to ethnic background in children: the Generation R Study
Rotterdam, Netherlands
Sun 23 10:00
OC4
Oral Communications: Epidemiology
Maternal antenatal 25(OH)-vitamin D status is associated with offspring muscle strength at 4 years of age
Southampton, UK
Sun 23 10:10
OC5
Oral Communications: Epidemiology
Novel musculoskeletal phenotypes during childhood for epidemiological studies
Oxford, UK
Sun 23 10:20
OC6
Oral Communications: Epidemiology
Role of bone-associated loci identified in GWAS meta-analyses in the context of longitudinal pediatric BMD in European Americans
(Philadelphia, USA)
Sun 23 10:30
Charles Slemenda Award
Sun 23 10:35
Coffee
Sun 23 11:00
The Fracturing Child: Biology
Chairs: Rachel Gafni (Bethesda, USA) & Gerard Pals (Amsterdam, Netherlands)
Sun 23 11:00
IS3
The Fracturing Child: Biology
Bone structure and fractures
Rochester, USA
Sun 23 11:30
IS4
The Fracturing Child: Biology
The biology of bone revealed through bone biopsy
Los Angeles, USA
Sun 23 12:00
Oral Communications: Biology
Sun 23 12:00
OC7
Oral Communications: Biology
The PPP6R3/LRP5 locus influences lean mass in children of different ethnic background and highlights pleiotropic effects and muscle-bone interactions
Rotterdam, Netherlands
Sun 23 12:10
OC8
Oral Communications: Biology
Generation of the first mouse model of Autosomal Dominant Type II Osteopetrosis ADO2) harbouring the pG213R-clc7 mutation
Rome, Italy
Sun 23 12:20
OC9
Oral Communications: Biology
EPO signaling and hematopoietic expansion as causes of osteoporosis in a thalassemia mouse model
New York, USA
Sun 23 12:30
OC10
Oral Communications: Biology
Phenotypic dissection of bone mineral density facilitates the identification of skeletal site specificity on the genetic regulation of bone
(Bristol, UK)
Sun 23 12:40
OC11
Oral Communications: Biology
Connectivity map-based discovery of novel compounds that induce osteoblast differentiation
Rotterdam, The Netherlands
Sun 23 12:50
OC12
Oral Communications: Biology
Improvement of collagen synthesis in fibroblasts of Brtl model for Osteogenesis Imperfecta following lentiviral-shRNA-mediated down-expression of mutant Col1a1 allele
Nantes, France
Sun 23 13:00
Lunch
Sun 23 13:30
Posters (odd numbers presented)
Sun 23 14:30
Oral Posters
Chairs: Nick Bishop (Sheffield, UK) & Coen Netelenbos (Amsterdam, Netherlands)
Sun 23 14:30
OP1
Oral Posters
Skeletal effects of hypothyroidism are mediated by thyroid hormone receptor
London, UK
Sun 23 14:35
OP2
Oral Posters
High FSH serum levels may support the altered bone remodeling in Turner Syndrome patients
Bari, Italy
Sun 23 14:40
OP3
Oral Posters
Calcimimetics as adjunct therapy in XLH: 18 months experience
Kansas City, USA
Sun 23 14:45
OP4
Oral Posters
A new start-codon in IFITM5 causes Osteogenesis Imperfecta Type V
Cologne, Germany
Sun 23 14:50
OP5
Oral Posters
Abstract withdrawn
Sun 23 14:55
OP6
Oral Posters
Children with nephrotic syndrome have increased tibial bone area but similar volumetric bone mineral density to healthy controls
Southampton, UK
Sun 23 15:00
OP7
Oral Posters
Bone Mineralization Density Distribution, bone formation rate and bone turnover markers in a cohort of children with CKD before and after growth hormone treatment
Vienna, Austria
Sun 23 15:05
OP8
Oral Posters
Quantitative measurement of abnormal bone quality and strength with bone microarchitecture and rod-plate configuration in osteopenic adolescent idiopathic scoliosis (AIS)
Hong Kong, China
Sun 23 15:10
Oral Posters
Chairs: Nick Bishop (Sheffield, UK) & Coen Netelenbos (Amsterdam, Netherlands)
Sun 23 15:10
OP9
Oral Posters
Anticalciuric effect of recombinant PTH in patients with activating mutations of the calcium-sensing receptor causing autosomal dominant hypocalcaemia-hypercalciuria (ADHH)
Paris, France
Sun 23 15:15
OP10
Oral Posters
Metacarpal width, length, medullary diameter and cortical thickness in hypophosphatemic rickets
Esbjerg, Denmark
Sun 23 15:20
OP11
Oral Posters
Artistic gymnasts display micro-architectural advantages over trampolining and tumbling gymnasts: A high resolution peripheral quantitative computed tomography study
Calgary, Canada
Sun 23 15:25
OP12
Oral Posters
The bone/vessels interplay in teenagers with chronic kidney disease
Lyons, France
Sun 23 15:30
OP13
Oral Posters
Long-term effects of bisphosphonate therapy in children with osteogenesis imperfecta
Sydney, Australia
Sun 23 15:35
OP14
Oral Posters
Inflammation and glucocorticoid therapy impair skeletal modeling during growth following Crohn Disease diagnosis
(Philadelphia, USA)
Sun 23 15:40
OP15
Oral Posters
Dissecting the role of osteoblast derived nitric oxide in bone remodeling
Houston, USA
Sun 23 15:45
Coffee
Sun 23 16:15
Rare diseases
Chairs: Paul Baldock (Sydney, Australia) & Frank Rauch (Montreal, Canada)
Sun 23 16:15
IS5
Rare diseases
Acrodysostosis
Paris, France
Sun 23 16:45
IS6
Rare diseases
Gaucher
Genoa, Italy
Sun 23 17:15
IS7
Rare diseases
Osteogenesis Imperfecta
Amsterdam, Netherlands
Sun 23 17:45
Break
Sun 23 18:00
Dinner Symposium: Differentiating unusual causes of rickets and hypercalcemia
Supported by: Alexion Pharmaceuticals
Sun 23 18:00
Scientific presentations
WILLEM BURGER AUDITORIUM (3RD FLOOR)
Sun 23
Scientific presentations
Welcome/Introduction/Case Introduction
Chicago, USA
Sun 23
Scientific presentations
New insights on vitamin D metabolism: the role of 24-hydroxylase
Münster, Germany
Sun 23
Scientific presentations
Hormone independent hypercalcemia: Jansen’s metaphyseal chondrodysplasia
(Boston, USA)
Sun 23
Scientific presentations
Hypophosphatasia: the impact of alkaline phosphatase deficiency
Sheffield, UK
Sun 23
Scientific presentations
Case Discussion: pathogenesis and differential diagnosis
Sun 23 20:00
Dinner
ARCADIS ZAAL (1ST FLOOR)
Mon 24 08:30
The Fracturing Child: Diagnostics
Chairs: Paul Dimitri (Sheffield, UK) & Craig Munns (Sydney, Australia)
Mon 24 08:30
IS8
The Fracturing Child: Diagnostics
Non-invasive assessment of bone structure and strength using QCT and MRI
(Philadelphia, USA)
Mon 24 09:00
IS9
The Fracturing Child: Diagnostics
DXA and Vertebral Fracture Assessment
Manchester, UK
Mon 24 09:30
Oral Communications: Diagnostics
Mon 24 09:30
OC13
Oral Communications: Diagnostics
Level of calcium intake modifies the correlation between parathyroid hormone and 25-hydroxyvitamin D: A proposal of adequate 25-hydroxyvitamin D levels in children
Santiago, Chile
Mon 24 09:40
OC14
Oral Communications: Diagnostics
What DXA measurement sites are best for bone health assessment in children? Effect of inter-machine differences on bone outcomes from the Bone Mineral Density in Childhood Study (BMDCS)
(Philadelphia, USA)
Mon 24 09:50
OC15
Oral Communications: Diagnostics
Bone Health Index: Swiss children have less in the bank than a generation ago
Hørsholm, Denmark
Mon 24 10:00
OC16
Oral Communications: Diagnostics
Longitudinal analysis of volumetric density, size and strength towards the end of skeletal maturation in Gambian males habituated to low calcium intake
(Cambridge, UK)
Mon 24 10:10
OC17
Oral Communications: Diagnostics
Determinants of bone mineral density in long-term adult survivors of childhood cancer
Rotterdam, Netherlands
Mon 24 10:20
OC18
Oral Communications: Diagnostics
Trabecular bone score (TBS) applied to normal children's lumbar spine DXA scans
Manchester, UK
Mon 24 10:30
Coffee
Mon 24 11:00
The Fracturing Child: Therapeutics
Chairs: Francis Glorieux (Montreal, Canada) & Farzana Perwad (San Francisco, USA)
Mon 24 11:00
IS10
The Fracturing Child: Therapeutics
Medical therapies: present and future
Brisbane, Australia
Mon 24 11:30
IS11
The Fracturing Child: Therapeutics
Other therapeutic options: nutrition, vitamin D, physical activity
Boston, USA
Mon 24 12:00
Oral Communications: Miscellaneous
Mon 24 12:00
OC19
Oral Communications: Miscellaneous
New therapeutic approach in OI VI - suppression of bone resorption using the RANKL antibody denosumab
Cologne, Germany
Mon 24 12:10
OC20
Oral Communications: Miscellaneous
Exercise completed when young provides lifelong benefit to cortical bone structure and estimated strength
Indianapolis, USA
Mon 24 12:20
OC21
Oral Communications: Miscellaneous
A randomized, double-blind, placebo-controlled trial of alendronate treatment for fibrous dysplasia of bone
Bethesda, USA
Mon 24 12:30
OC22
Oral Communications: Miscellaneous
Prolidase deficient mice are osteoporotic in early life
Sheffield, UK
Mon 24 12:40
OC23
Oral Communications: Miscellaneous
Switching from alendronate to RANKL blockade alters bone properties after 14 weeks of therapy in the oim/oim mouse
New York, USA
Mon 24 12:50
OC24
Oral Communications: Miscellaneous
Fibroblast growth factor 23 plasma levels are elevated with early chronic kidney disease and positively associated with steroid based versus steroid free immunosuppression in pediatric renal transplant patients
Houston, USA
Mon 24 13:00
Lunch
Mon 24 13:30
Posters (even numbers presented)
Mon 24 14:30
Chronic diseases
Chairs: Wolfgang Högler (Birmingham, UK) & Carmen Wilson (Memphis, USA)
Mon 24 14:30
IS12
Chronic diseases
IBD, bone, fractures and inflammation
Gothenburg, Sweden
Mon 24 15:00
IS13
Chronic diseases
Muscle-bone interaction in pediatric bone diseases
Montreal, Canada
Mon 24 15:30
Coffee
Mon 24 16:00
Chronic diseases
Chairs: Mary Leonard (Philadelphia, USA) & Agnès Linglart (Paris, France)
Mon 24 16:00
Oral Communications: Chronic diseases
Mon 24 16:00
OC25
Oral Communications: Chronic diseases
Wnt/ ß-catenin: A candidate pathway for bone repair in Neurofibromatosis Type-1
Toronto, Canada
Mon 24 16:10
OC26
Oral Communications: Chronic diseases
Vertebral fractures in the 3 year period following steroid initiation among children with chronic illnesses
Calgary, Canada
Mon 24 16:20
OC27
Oral Communications: Chronic diseases
Serum vitamin D level can affect the treatment outcome of whole-body vibration (WBV) for low bone mass in girls with Adolescent Idiopathic Scoliosis (AIS)
Hong Kong, Hong Kong
Mon 24 16:30
OC28
Oral Communications: Chronic diseases
Bone mineral density at diagnosis determines fracture rate in children treated according to the DCOG-ALL9 protocol.
Rotterdam, Netherlands
Mon 24 16:40
OC29
Oral Communications: Chronic diseases
Mineral metabolism, cortical volumetric bone mineral density and fracture risk in childhood chronic kidney disease
Philadelphia, USA
Mon 24 16:50
OC30
Oral Communications: Chronic diseases
Alteration of Wnt/Beta-Catenin signaling in HIV-infected youths: A mechanism leading to impaired bone health?
Milan, Italy
Mon 24 17:00
IS14
Oral Communications: Chronic diseases
Type I Diabetes
Munich, Germany
Mon 24 17:30
Satellite Symposium: Vitamin D: Shifting the Status
Supported by: Danone Baby Nutrition
Chair: Nick Bishop (Sheffield, UK)
Mon 24
Satellite Symposium: Vitamin D: Shifting the Status
Global burden of vitamin D deficiency
Dubai , UAE
Mon 24
Satellite Symposium: Vitamin D: Shifting the Status
Food based strategies for increasing vitamin D status in young children
Cork, Ireland
Mon 24
Satellite Symposium: Vitamin D: Shifting the Status
Vitamin D deficiency in adolescence
Boston, USA
Mon 24 19:10
Satellite Symposium: Vitamin D: Shifting the Status
Buses depart for Conference Party from Conference Centre entrance immediately following Satellite Symposium
Mon 24 19:30
Conference Party
Buses return to the Conference Centre from 22:30, calling at the Hilton, Manhattan and Bilderberg hotels. It is a short walk from the disembarkation point to the Inntel, Maritime and StayOK hotels
Supported by: DANONE BABY NUTRITION
Location: PADDLESTEAMER DE MAJESTEIT
Tue 25 08:30
Presentation of Awards
Chairs: Maria Luisa Bianchi (Milan, Italy) & Coen Netelenbos (Amsterdam, Netherlands)
Tue 25 08:40
Late Breaking Abstracts
Chairs: Nick Bishop (Sheffield, UK) & Craig B Langman (Chicago, USA)
Tue 25 08:40
LB1
Late Breaking Abstracts
Influence of age and gender on spine bone density and TBS microarchitectural texture parameters in infants
Pessac, France
Tue 25 08:50
LB2
Late Breaking Abstracts
WNT1 mutations in early-onset osteoporosis and osteogenesis imperfecta identify a key WNT ligand regulating bone mass
Helsinki, Finland
Tue 25 09:00
Paediatric cancer and bone: Round Table
Chairs: Sabine de Muinck Keizer-Schrama (Rotterdam, Netherlands) & Roman Lorenc (Warsaw, Poland)
Tue 25 09:00
IS15
Paediatric cancer and bone: Round Table
Bone and endocrine side-effects in childhood Hodgkins lymphoma and acute lymphoblastic leukemia
Rotterdam, Netherlands
Tue 25 09:30
IS16
Paediatric cancer and bone: Round Table
Childhood cancer and fractures
Memphis, USA
Tue 25 10:00
Paediatric cancer and bone: Round Table
Round Table discussion
Tue 25 10:20
Coffee
Tue 25 10:45
Obesity as a bone disease: Round Table
Chairs: Aenor Sawyer (San Francisco, USA) & Eckhard Schönau (Cologne, Germany)
Tue 25 10:45
IS17
Obesity as a bone disease: Round Table
Bone as an endocrine organ
Tue 25 11:15
IS18
Obesity as a bone disease: Round Table
Obesity and skeletal health
Sheffield, UK
Tue 25 11:45
Obesity as a bone disease: Round Table
Round Table discussion
Tue 25 12:05
Closing Remarks

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