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Sat 10 Jun 2017
Sat 10
Sun 11 Jun 2017
Sun 11
Mon 12 Jun 2017
Mon 12
Tue 13 Jun 2017
Tue 13
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Saturday 10 June
6 sessions
07:30 - 08:45
Registration
12:30 - 14:30
Networking session
14:50 - 16:20
Children's bones in health and disease
Children's bones in health and disease
Bone Fraglity
Outi Mäkitie
Helsinki, Finland
Children's bones in health and disease
Bone Mineralisation
Keiichi Ozono
Suita, Japan
Children's bones in health and disease
Bone Dyspasia
Melita Irving
London, UK
Children's bones in health and disease
Abnormality of calcium and phosphate homeostasis
Agnès Linglart, MD, PhD
Paris, France
16:30 - 17:30
Workshop: Osteogenesis imperfecta
Workshop: Osteogenesis imperfecta
Introduction
Christine Burren
UK
Workshop: Osteogenesis imperfecta
Current approaches to treatment
Outi Mäkitie
Helsinki, Finland
Workshop: Osteogenesis imperfecta
What does the future hold
Leanne Ward
Ontario , Canada
17:30 - 17:45
Welcome Address
18:00 - 19:30
Satellite symposium: Novel insights into the broad clinical manifestations and management of XLH
Sunday 11 June
12 sessions
07:30 - 08:45
Registration
08:00 - 08:45
Meet the expert
Meet the expert
Prevention of rickets and osteomalacia - why, how?
Wolfgang Högler
Linz, Austria
08:00 - 08:45
Meet the expert
Meet the expert
Physical activity to improve bone stability
08:00 - 08:45
Meet the expert
Meet the expert
Molecular mechanisms of disorders with abnormal bone mass and fragility
Uwe Kornak
Berlin, Germany
09:00 - 10:00
What is new: 2 years in review
IS01
What is new: 2 years in review
Highlights in basic bone research
Roland Baron
Boston, USA
IS02
What is new: 2 years in review
Highlights in clinical bone research
Frank Rauch
Montreal, Canada
10:30 - 11:00
Charles Slemenda Award
Charles Slemenda Award
Charles Slemenda Award
Frank Rauch
Montreal, Canada
11:00 - 11:40
Oral communications: Genetics
OC1
Oral communications: Genetics
NBAS variants causing a novel form of inherited bone fragility
Meena Balasubramanian
Sheffield, UK
OC2
Oral communications: Genetics
Methylation patterns at the novel DMR of GNAS (GNAS-AS2) in pseudohypoparathyroidism 1B (PHP1B or iPPSD3) subtypes
Agnès Linglart, MD, PhD
Paris, France
OC3
Oral communications: Genetics
Principal component-derived bone density phenotypes and genetic regulation of the pediatric skeleton
Jonathan Mitchell
Philadelphia, USA
OC4
Oral communications: Genetics
25-hydroxyvitamin D response to antenatal cholecalciferol supplementation is associated with common vitamin D related genetic variants: findings from the MAVIDOS trial
Rebecca Moon
Southampton, UK
11:40 - 12:00
Poster Pitching
P013
Poster Pitching
Longitudinal evaluation of bone mass, geometry and metabolism in adolescent male athletes. The PRO-BONE study
Dimitris Vlachopoulos
Exeter, UK
P019
Poster Pitching
Zebrafish as model organism for craniosynostosis
Rabea Bleumel
Würzburg, Germany
P027
Poster Pitching
Sex and iron modify fibroblast growth factor 23 concentrations in 1-year-old children
Elisa Holmlund-Suila
Helsinki, Finland
P039
Poster Pitching
Cystinosin deficiency affects bone phenotype
Giulia Battafarano
Rome, Italy
P065
Poster Pitching
A novel form of congenital rickets due to a recurrent gain of function mutation in CYP3A4
Christine Rodda
Melbourne, Australia
P079
Poster Pitching
Assessment of a semi-automated software program for the identification of vertebral fractures in children
Fawaz Alqahtani
Lucknow, India
P125
Poster Pitching
Identification and characterization of a novel microRNA inhibiting osteoblast functions by suppressing actin polymerization
Aljaz John
Lucknow, India
P141
Poster Pitching
Unique correlation pattern between cortical trabecular bone qualities and standard dynamometer handgrip strength in girls with adolescent idiopathic scoliosis (AIS)?
Ka-Yee Cheuk
Shatin, Hong Kong
P161
Poster Pitching
Early-life vitamin D status and bone mass at five years in a prospective birth cohort study
Carol Chaomh
Cork, Ireland
P189
Poster Pitching
A deep phenotyping of autosomal dominant osteopetrosis type 2 (ADO2) mouse model revealed multiorgan dysfunctions
Antonio Maurizi
14:00 - 15:30
Basic bone biology: osteoblasts, osteocytes, microstructure
IS03
Basic bone biology: osteoblasts, osteocytes, microstructure
Bone cells in health and disease
Antonella Forlino
Pavia, Italy
IS04
Basic bone biology: osteoblasts, osteocytes, microstructure
Cortical bone structure and material properties
Björn Busse
Hamburg, Germany
IS05
Basic bone biology: osteoblasts, osteocytes, microstructure
Skeletal mineralization – enzymes and animal models
José Millán
La Jolla, USA
15:30 - 16:30
Oral communications: Epidemiology and Nutrition
OC5
Oral communications: Epidemiology and Nutrition
Eight-year longitudinal analysis of physical activity and bone strength during adolescence: the Iowa Bone Development Study
Kathleen Janz
Iowa City, USA
OC6
Oral communications: Epidemiology and Nutrition
Lean mass accretion increases during summer and positively associates with vitamin D status in healthy children 2-8 years
Neil Brett
Montreal, Canada
OC7
Oral communications: Epidemiology and Nutrition
The effect of antenatal iron supplementation on fibroblast growth factor-23 concentration in mothers and infants: a randomised controlled trial in rural Kenya
Vickie Braithwaite
Cambridge, UK
OC8
Oral communications: Epidemiology and Nutrition
Effective therapeutic control of curve progression using calcium and vitamin D supplementation for adolescent idiopathic scoliosis – a randomized double-blinded placebo-controlled trial
Tsz Lam
Hong Kong, Hong Kong
OC9
Oral communications: Epidemiology and Nutrition
Calcium carbonate supplementation of pregnant rural Gambian mothers alters offspring IGF-1 at age 7.5 years in a sex-dependent manner
Ann Prentice
Cambridge, UK
OC10
Oral communications: Epidemiology and Nutrition
Inadequate vitamin D status adversely affects trabecular bone mineral density in 14-18 year old adolescents
Taryn Smith
Guildford, Surrey
17:00 - 18:00
Muscle and bone
IS06
Muscle and bone
The mechanobiology of the growing skeleton
Bettina Willie
Montreal, Canada
IS07
Muscle and bone
A role for leptin as a myokine mediating muscle-bone interactions
Mark Hamrick
Atlanta, USA
18:15 - 19:45
Satellie symposium: Hypophosphatasia in children: strengthening the foundations for managing a complex disease
Monday 12 June
9 sessions
07:30 - 08:45
Registration
08:00 - 08:45
Meet the expert
Meet the expert
The genetic basis of bone disorders- what every clinician needs to know
Outi Mäkitie
Helsinki, Finland
Meet the expert
Bone pain: mechanisms and intervention
Jacqui Clinch
Bath, UK
Meet the expert
DEXA – how, when and what?
Nicola Crabtree
Birmingham, UK
09:00 - 10:30
Genetics and Epigenetics: The impact for rare bone diseases
IS08
Genetics and Epigenetics: The impact for rare bone diseases
Next generation sequencing and genome editing, game changers in the field of skeletal research
Uwe Kornak
Berlin, Germany
IS09
Genetics and Epigenetics: The impact for rare bone diseases
Skeletal dysplasias
Melita Irving
London, UK
IS10
Genetics and Epigenetics: The impact for rare bone diseases
Arterial calcification syndromes: causes and treatments
Frank Rutsch
Münster, Germany
11:00 - 11:40
Oral communications: Muscle and bone mineral density
OC11
Oral communications: Muscle and bone mineral density
The effect of whole body vibration training on bone and muscle function in children with osteogenesis imperfecta and limited mobility: a randomized controlled pilot trial
Wolfgang Högler
Linz, Austria
OC12
Oral communications: Muscle and bone mineral density
Fracture incident rate and growth in a nationwide cohort of boys with Duchenne muscular dystrophy
Jarod Wong
Glasgow, UK
OC13
Oral communications: Muscle and bone mineral density
Enterococccus faecium abundance in gut microbiome is associated with higher bone mineral density in school age children
Carolina Medina-Gomez
Rotterdam, Netherlands
OC14
Oral communications: Muscle and bone mineral density
Body composition and associated biomarkers as determinants of bone mineral density in children 6-8 years of age - the Physical Activity and Nutrition in Children (PANIC) study
Sonja Soininen
Kuopio, Finland
11:40 - 12:00
Poster pitching
P004
Poster pitching
Bone mass tracks into teenage years
Maria Rønne
Odense, Denmark
P030
Poster pitching
Outcomes of zoledronic acid use in paediatric conditions
Margaret Zacharin
P034
Poster pitching
Identification of bone remodelling alterations in Gorham-Stout disease
Michela Rossi
Melbourne, Australia
P054
Poster pitching
The influence of immune dysregulation on bone metabolism in children with inflammatory bowel disease: the potential for bone as a secondary lymphoid organ
Garath Penman
Sheffield, UK
P080
Poster pitching
Bone age assessment using Greulich and Pyle and Tanner-Whitehouse methods: a systematic review
Khalaf Alshamrani
Sheffield, UK
P102
Poster pitching
Do measures of adiposity and muscle cross-sectionally predict the health of weight-bearing bones in 11-12 year old Australian children? A population-based study
Peter Simm
Melbourne, Australia
P114
Poster pitching
Rare copy number variants in array-based comparative genomic hybridization in early-onset skeletal fragility
Alice Costantini
Stockholm, Sweden
P132
Poster pitching
Anti-RANKL treatment in a murine model of fibrous dysplasia
Biagio Palmisano
Rome, Italy
P142
Poster pitching
Walking within 12 months of age is related to higher whole body lean mass and bone mineral density in children at 3 years of age
Hope Weiler
Ottawa, Canada
P182
Poster pitching
Osteonecrosis results in significant long term morbidity in patients with acute lymphoblastic leukaemia
Nadia Amin
Leeds Teaching Hospital, Leeds, UK
P202
Poster pitching
Osteosarcoma-derived extracellular vesicles induce tumoral-like phenotypes in normal cells
Enrica Urciuoli
Rome, Italy
14:00 - 15:00
Rare bone diseases
IS11
Rare bone diseases
Overview: why study rare bone diseases?
Hans Leeuwen
Rotterdam, Netherlands
IS12
Rare bone diseases
The ERNS as a tool for the European research on rare diseases
Kassim Javaid
Oxford, UK
15:00 - 15:30
Oral communications: Bone fragility and metabolism
OC15
Oral communications: Bone fragility and metabolism
Fractures in school age children in relation to sex, ethnic background and bone mineral density: the Generation R study
Olja Grgic
Rotterdam, Netherlands
OC16
Oral communications: Bone fragility and metabolism
Pediatric hypophosphatasia – a retrospective single-center chart review of 50 children
Marius Vogt
Würzburg, Germany
OC17
Oral communications: Bone fragility and metabolism
Vertebral fractures in children with chronic inflammatory and/or disabling conditions: the SNAP study
Nicola Crabtree
Birmingham, UK
16:00 - 17:30
Chronic disease and bone
IS13
Chronic disease and bone
Osteoporosis in boys with Duchenne Muscular Dystrophy: morbidity, mechanisms and the path forward
Leanna Ward
Ottawa, Canada
IS14
Chronic disease and bone
Bone, body composition and metabolic abnormalities after allogeneic hematopoietic stem cell transplantation during childhood
Sogol Mostoufi-Moab
Philadelphia, USA
IS15
Chronic disease and bone
An integrated approach to kidney bone disease across the spectrum
Craig Langman
Chicago, USA
17:30 - 18:30
Workshop: Novel perspectives in two rare bone disorders
Tuesday 13 June
10 sessions
07:30 - 08:45
Registration
08:00 - 08:45
Meet the expert
Meet the expert
Recurrent fractures in childhood – causes, investigations and management
Nick Bishop
Sheffield, UK
Meet the expert
From bench to bedside: Looking at the use of HR CT and QCT in a diagnostic setting
Kate Ward
Southampton, UK
Meet the expert
Managing hypercalcemia in neonates/infants
Agnès Linglart, MD, PhD
Paris, France
09:00 - 10:00
Nutrition and bone health
IS16
Nutrition and bone health
Body composition and physical activity
Bonny Specker
South Dakota, USA
IS17
Nutrition and bone health
Factors influencing peak bone mass
Nick Harvey
10:10 - 11:00
Oral communications: Miscellaneous
OC18
Oral communications: Miscellaneous
Stimulation of angiogenesis and osteogenesis by enhanced preosteoclast platelet derived growth factor type BB attenuates glucocorticoid-induced osteoporosis in growing mice
Janet Crane
Baltimore, USA
OC19
Oral communications: Miscellaneous
Mesenchymal stromal stem cells in pediatric orthopedic oncology, focus on osteosarcoma
Valérie Trichet
Nantes, France
OC20
Oral communications: Miscellaneous
Autoimmune hyperphosphatemic tumoral calcinosis
Mary Ramnitz
Bethesda, USA
OC21
Oral communications: Miscellaneous
Scoliosis in fibrous dysplasia/McCune-Albright syndrome
Alison Boyce
Bethesda, USA
OC22
Oral communications: Miscellaneous
Type I collagen C-propeptide cleavage deficiency increases bone mineralization and alters bone cell differentiation
Joan Marini
Bethesda, USA
11:30 - 12:30
Signalling pathways and their significance for bone health and disease (concurrently with Allied Health Professionals session)
IS18
Signalling pathways and their significance for bone health and disease (concurrently with Allied Health Professionals session)
Phosphate and FGF23 signalling
Justine Bacchetta
Lyons, France
IS19
Signalling pathways and their significance for bone health and disease (concurrently with Allied Health Professionals session)
Signalling pathways and their significance for bone health and disease. PTH/cAMP/PKA
Dr. Anya Rothenbuhler
Paris, France
IS20
Signalling pathways and their significance for bone health and disease (concurrently with Allied Health Professionals session)
Canonical Wnt signaling in bone health and disease
Wim Hul
Antwerp, Belgium
11:30 - 12:30
Allied health professionals session (concurrently with signaling pathways symposium)
P097
Allied health professionals session (concurrently with signaling pathways symposium)
Evaluation of the use of body quantitative computed tomography for the assessment of the tibia in children with neurofibromatosis 1
Alex Ireland
Manchester, UK
P020
Allied health professionals session (concurrently with signaling pathways symposium)
Age at onset of walking affects bone mineral content in early childhood
Sarah Valkama
Helsinki, Finland
P007
Allied health professionals session (concurrently with signaling pathways symposium)
Effects of a 8-month physical activity and nutrition-induced weight loss program on bone health of obese adolescents
Elodie Chaplais
Aubiere, France
P101
Allied health professionals session (concurrently with signaling pathways symposium)
Establishing the clinical need for a dedicated service for children and adolescents with osteogenesis imperfecta in the Republic of Ireland
Ciara McDonnell
Dublin, Ireland
P204
Allied health professionals session (concurrently with signaling pathways symposium)
Is a modified version of the Childhood Health Assessment Questionnaire (CHAQ) a useful tool to identify the level of disability in children with osteogenesis imperfecta?
Suzanne Bell
Birmingham, UK
P208
Allied health professionals session (concurrently with signaling pathways symposium)
Social barriers and needs of children with osteogenesis imperfecta (OI): a qualitative descriptive interview-based study
Jerzy Konstantynowicz
Bialystok, Poland
13:10 - 14:10
Treating children’s bones: present and future
IS21
Treating children’s bones: present and future
BOOSTB4: Boost Brittle Bones Before Birth, A clinical trial on pre- and/or postnatal stemm cell transplantation for treatment of osteogenesis imperfecta
Cecilia Götherström
Huddinge, Sweden
IS22
Treating children’s bones: present and future
Role of microRNAs in the development of osteosarcoma
Eric Hesse
Huddinge, Sweden
14:15 - 15:05
Oral communications: Hot topics
OC23
Oral communications: Hot topics
Sustained radiographic and functional improvements with asfotase alfa treatment from up to 7 years in children with hypophosphatasia
Scott Moseley
Indianapolis, USA
OC24
Oral communications: Hot topics
KRN23 effects on phosphate and vitamin D dysregulation in children <5 years old with x-linked hypophosphatemia (XLH)
Erik Imel
Indianapolis, USA
OC25
Oral communications: Hot topics
Biochemical and physical function outcomes after 5 years of treatment with asfotase alfa in adolescents and adults with hypophosphatasia: phase 2 study results
Scott Moseley
Indianapolis, USA
OC26
Oral communications: Hot topics
A randomized, open-label phase 2 study of KRN23, an investigational fully human anti-FGF23 monoclonal antibody, in children with x-linked hypophosphatemia (XLH)
Prof Raja Padidela
Manchester, UK
LB1
Oral communications: Hot topics
Treatment with a novel activin receptor IIB ligand trap improves muscle mass and bone geometry in a mouse model of severe osteogenesis imperfecta
Josephine Tauer
Montreal, Canada
15:10 - 15:25
Presentation of awards
15:25 - 15:30
Close and final remarks
Fawaz Alqahtani
Lucknow, India
Sun 11
11:49
P079
Poster Pitching
Assessment of a semi-automated software program for the identification of vertebral fractures in children
Fawaz Alqahtani
Lucknow, India
Khalaf Alshamrani
Sheffield, UK
Mon 12
11:46
P080
Poster pitching
Bone age assessment using Greulich and Pyle and Tanner-Whitehouse methods: a systematic review
Khalaf Alshamrani
Sheffield, UK
Nadia Amin
Leeds Teaching Hospital, Leeds, UK
Mon 12
11:53:30
P182
Poster pitching
Osteonecrosis results in significant long term morbidity in patients with acute lymphoblastic leukaemia
Nadia Amin
Leeds Teaching Hospital, Leeds, UK
Justine Bacchetta
Lyons, France
Tue 13
11:30
IS18
Signalling pathways and their significance for bone health and disease (concurrently with Allied Health Professionals session)
Phosphate and FGF23 signalling
Justine Bacchetta
Lyons, France
Meena Balasubramanian
Sheffield, UK
Sun 11
11:00
OC1
Oral communications: Genetics
NBAS variants causing a novel form of inherited bone fragility
Meena Balasubramanian
Sheffield, UK
Roland Baron
Boston, USA
Sun 11
09:00
IS01
What is new: 2 years in review
Highlights in basic bone research
Roland Baron
Boston, USA
Giulia Battafarano
Rome, Italy
Sun 11
11:46
P039
Poster Pitching
Cystinosin deficiency affects bone phenotype
Giulia Battafarano
Rome, Italy
Suzanne Bell
Birmingham, UK
Tue 13
11:58
P204
Allied health professionals session (concurrently with signaling pathways symposium)
Is a modified version of the Childhood Health Assessment Questionnaire (CHAQ) a useful tool to identify the level of disability in children with osteogenesis imperfecta?
Suzanne Bell
Birmingham, UK
Nick Bishop
Sheffield, UK
Tue 13
Meet the expert
Recurrent fractures in childhood – causes, investigations and management
Nick Bishop
Sheffield, UK
Rabea Bleumel
Würzburg, Germany
Sun 11
11:41:30
P019
Poster Pitching
Zebrafish as model organism for craniosynostosis
Rabea Bleumel
Würzburg, Germany
Alison Boyce
Bethesda, USA
Tue 13
10:40
OC21
Oral communications: Miscellaneous
Scoliosis in fibrous dysplasia/McCune-Albright syndrome
Alison Boyce
Bethesda, USA
Vickie Braithwaite
Cambridge, UK
Sun 11
15:50
OC7
Oral communications: Epidemiology and Nutrition
The effect of antenatal iron supplementation on fibroblast growth factor-23 concentration in mothers and infants: a randomised controlled trial in rural Kenya
Vickie Braithwaite
Cambridge, UK
Neil Brett
Montreal, Canada
Sun 11
15:40
OC6
Oral communications: Epidemiology and Nutrition
Lean mass accretion increases during summer and positively associates with vitamin D status in healthy children 2-8 years
Neil Brett
Montreal, Canada
Christine Burren
UK
Sat 10
Workshop: Osteogenesis imperfecta
Introduction
Christine Burren
UK
Björn Busse
Hamburg, Germany
Sun 11
14:30
IS04
Basic bone biology: osteoblasts, osteocytes, microstructure
Cortical bone structure and material properties
Björn Busse
Hamburg, Germany
Carol Chaomh
Cork, Ireland
Sun 11
11:53:30
P161
Poster Pitching
Early-life vitamin D status and bone mass at five years in a prospective birth cohort study
Carol Chaomh
Cork, Ireland
Elodie Chaplais
Aubiere, France
Tue 13
11:44
P007
Allied health professionals session (concurrently with signaling pathways symposium)
Effects of a 8-month physical activity and nutrition-induced weight loss program on bone health of obese adolescents
Elodie Chaplais
Aubiere, France
Ka-Yee Cheuk
Shatin, Hong Kong
Sun 11
11:52
P141
Poster Pitching
Unique correlation pattern between cortical trabecular bone qualities and standard dynamometer handgrip strength in girls with adolescent idiopathic scoliosis (AIS)?
Ka-Yee Cheuk
Shatin, Hong Kong
Jacqui Clinch
Bath, UK
Mon 12
Meet the expert
Bone pain: mechanisms and intervention
Jacqui Clinch
Bath, UK
Alice Costantini
Stockholm, Sweden
Mon 12
11:49
P114
Poster pitching
Rare copy number variants in array-based comparative genomic hybridization in early-onset skeletal fragility
Alice Costantini
Stockholm, Sweden
Nicola Crabtree
Birmingham, UK
Mon 12
Meet the expert
DEXA – how, when and what?
Nicola Crabtree
Birmingham, UK
Mon 12
15:20
OC17
Oral communications: Bone fragility and metabolism
Vertebral fractures in children with chronic inflammatory and/or disabling conditions: the SNAP study
Nicola Crabtree
Birmingham, UK
Janet Crane
Baltimore, USA
Tue 13
10:10
OC18
Oral communications: Miscellaneous
Stimulation of angiogenesis and osteogenesis by enhanced preosteoclast platelet derived growth factor type BB attenuates glucocorticoid-induced osteoporosis in growing mice
Janet Crane
Baltimore, USA
Antonella Forlino
Pavia, Italy
Sun 11
14:00
IS03
Basic bone biology: osteoblasts, osteocytes, microstructure
Bone cells in health and disease
Antonella Forlino
Pavia, Italy
Cecilia Götherström
Huddinge, Sweden
Tue 13
13:10
IS21
Treating children’s bones: present and future
BOOSTB4: Boost Brittle Bones Before Birth, A clinical trial on pre- and/or postnatal stemm cell transplantation for treatment of osteogenesis imperfecta
Cecilia Götherström
Huddinge, Sweden
Olja Grgic
Rotterdam, Netherlands
Mon 12
15:00
OC15
Oral communications: Bone fragility and metabolism
Fractures in school age children in relation to sex, ethnic background and bone mineral density: the Generation R study
Olja Grgic
Rotterdam, Netherlands
Mark Hamrick
Atlanta, USA
Sun 11
17:30
IS07
Muscle and bone
A role for leptin as a myokine mediating muscle-bone interactions
Mark Hamrick
Atlanta, USA
Nick Harvey
Tue 13
09:30
IS17
Nutrition and bone health
Factors influencing peak bone mass
Nick Harvey
Eric Hesse
Huddinge, Sweden
Tue 13
13:40
IS22
Treating children’s bones: present and future
Role of microRNAs in the development of osteosarcoma
Eric Hesse
Huddinge, Sweden
Wolfgang Högler
Linz, Austria
Sun 11
Meet the expert
Prevention of rickets and osteomalacia - why, how?
Wolfgang Högler
Linz, Austria
Mon 12
11:00
OC11
Oral communications: Muscle and bone mineral density
The effect of whole body vibration training on bone and muscle function in children with osteogenesis imperfecta and limited mobility: a randomized controlled pilot trial
Wolfgang Högler
Linz, Austria
Elisa Holmlund-Suila
Helsinki, Finland
Sun 11
11:44:30
P027
Poster Pitching
Sex and iron modify fibroblast growth factor 23 concentrations in 1-year-old children
Elisa Holmlund-Suila
Helsinki, Finland
Wim Hul
Antwerp, Belgium
Tue 13
12:10
IS20
Signalling pathways and their significance for bone health and disease (concurrently with Allied Health Professionals session)
Canonical Wnt signaling in bone health and disease
Wim Hul
Antwerp, Belgium
Erik Imel
Indianapolis, USA
Tue 13
14:25
OC24
Oral communications: Hot topics
KRN23 effects on phosphate and vitamin D dysregulation in children <5 years old with x-linked hypophosphatemia (XLH)
Erik Imel
Indianapolis, USA
Alex Ireland
Manchester, UK
Tue 13
11:30
P097
Allied health professionals session (concurrently with signaling pathways symposium)
Evaluation of the use of body quantitative computed tomography for the assessment of the tibia in children with neurofibromatosis 1
Alex Ireland
Manchester, UK
Melita Irving
London, UK
Sat 10
Children's bones in health and disease
Bone Dyspasia
Melita Irving
London, UK
Mon 12
09:30
IS09
Genetics and Epigenetics: The impact for rare bone diseases
Skeletal dysplasias
Melita Irving
London, UK
Kathleen Janz
Iowa City, USA
Sun 11
15:30
OC5
Oral communications: Epidemiology and Nutrition
Eight-year longitudinal analysis of physical activity and bone strength during adolescence: the Iowa Bone Development Study
Kathleen Janz
Iowa City, USA
Kassim Javaid
Oxford, UK
Mon 12
14:30
IS12
Rare bone diseases
The ERNS as a tool for the European research on rare diseases
Kassim Javaid
Oxford, UK
Aljaz John
Lucknow, India
Sun 11
11:50:30
P125
Poster Pitching
Identification and characterization of a novel microRNA inhibiting osteoblast functions by suppressing actin polymerization
Aljaz John
Lucknow, India
Jerzy Konstantynowicz
Bialystok, Poland
Tue 13
12:05
P208
Allied health professionals session (concurrently with signaling pathways symposium)
Social barriers and needs of children with osteogenesis imperfecta (OI): a qualitative descriptive interview-based study
Jerzy Konstantynowicz
Bialystok, Poland
Uwe Kornak
Berlin, Germany
Sun 11
Meet the expert
Molecular mechanisms of disorders with abnormal bone mass and fragility
Uwe Kornak
Berlin, Germany
Mon 12
09:00
IS08
Genetics and Epigenetics: The impact for rare bone diseases
Next generation sequencing and genome editing, game changers in the field of skeletal research
Uwe Kornak
Berlin, Germany
Tsz Lam
Hong Kong, Hong Kong
Sun 11
16:00
OC8
Oral communications: Epidemiology and Nutrition
Effective therapeutic control of curve progression using calcium and vitamin D supplementation for adolescent idiopathic scoliosis – a randomized double-blinded placebo-controlled trial
Tsz Lam
Hong Kong, Hong Kong
Craig Langman
Chicago, USA
Mon 12
17:00
IS15
Chronic disease and bone
An integrated approach to kidney bone disease across the spectrum
Craig Langman
Chicago, USA
Hans Leeuwen
Rotterdam, Netherlands
Mon 12
14:00
IS11
Rare bone diseases
Overview: why study rare bone diseases?
Hans Leeuwen
Rotterdam, Netherlands
Agnès Linglart, MD, PhD
Paris, France
Sat 10
Children's bones in health and disease
Abnormality of calcium and phosphate homeostasis
Agnès Linglart, MD, PhD
Paris, France
Sun 11
11:10
OC2
Oral communications: Genetics
Methylation patterns at the novel DMR of GNAS (GNAS-AS2) in pseudohypoparathyroidism 1B (PHP1B or iPPSD3) subtypes
Agnès Linglart, MD, PhD
Paris, France
Tue 13
Meet the expert
Managing hypercalcemia in neonates/infants
Agnès Linglart, MD, PhD
Paris, France
Outi Mäkitie
Helsinki, Finland
Sat 10
Children's bones in health and disease
Bone Fraglity
Outi Mäkitie
Helsinki, Finland
Sat 10
Workshop: Osteogenesis imperfecta
Current approaches to treatment
Outi Mäkitie
Helsinki, Finland
Mon 12
Meet the expert
The genetic basis of bone disorders- what every clinician needs to know
Outi Mäkitie
Helsinki, Finland
Joan Marini
Bethesda, USA
Tue 13
10:50
OC22
Oral communications: Miscellaneous
Type I collagen C-propeptide cleavage deficiency increases bone mineralization and alters bone cell differentiation
Joan Marini
Bethesda, USA
Antonio Maurizi
Sun 11
11:55
P189
Poster Pitching
A deep phenotyping of autosomal dominant osteopetrosis type 2 (ADO2) mouse model revealed multiorgan dysfunctions
Antonio Maurizi
Ciara McDonnell
Dublin, Ireland
Tue 13
11:51
P101
Allied health professionals session (concurrently with signaling pathways symposium)
Establishing the clinical need for a dedicated service for children and adolescents with osteogenesis imperfecta in the Republic of Ireland
Ciara McDonnell
Dublin, Ireland
Carolina Medina-Gomez
Rotterdam, Netherlands
Mon 12
11:20
OC13
Oral communications: Muscle and bone mineral density
Enterococccus faecium abundance in gut microbiome is associated with higher bone mineral density in school age children
Carolina Medina-Gomez
Rotterdam, Netherlands
José Millán
La Jolla, USA
Sun 11
15:00
IS05
Basic bone biology: osteoblasts, osteocytes, microstructure
Skeletal mineralization – enzymes and animal models
José Millán
La Jolla, USA
Jonathan Mitchell
Philadelphia, USA
Sun 11
11:20
OC3
Oral communications: Genetics
Principal component-derived bone density phenotypes and genetic regulation of the pediatric skeleton
Jonathan Mitchell
Philadelphia, USA
Rebecca Moon
Southampton, UK
Sun 11
11:30
OC4
Oral communications: Genetics
25-hydroxyvitamin D response to antenatal cholecalciferol supplementation is associated with common vitamin D related genetic variants: findings from the MAVIDOS trial
Rebecca Moon
Southampton, UK
Scott Moseley
Indianapolis, USA
Tue 13
14:15
OC23
Oral communications: Hot topics
Sustained radiographic and functional improvements with asfotase alfa treatment from up to 7 years in children with hypophosphatasia
Scott Moseley
Indianapolis, USA
Tue 13
14:35
OC25
Oral communications: Hot topics
Biochemical and physical function outcomes after 5 years of treatment with asfotase alfa in adolescents and adults with hypophosphatasia: phase 2 study results
Scott Moseley
Indianapolis, USA
Sogol Mostoufi-Moab
Philadelphia, USA
Mon 12
16:30
IS14
Chronic disease and bone
Bone, body composition and metabolic abnormalities after allogeneic hematopoietic stem cell transplantation during childhood
Sogol Mostoufi-Moab
Philadelphia, USA
Keiichi Ozono
Suita, Japan
Sat 10
Children's bones in health and disease
Bone Mineralisation
Keiichi Ozono
Suita, Japan
Prof Raja Padidela
Manchester, UK
Tue 13
14:45
OC26
Oral communications: Hot topics
A randomized, open-label phase 2 study of KRN23, an investigational fully human anti-FGF23 monoclonal antibody, in children with x-linked hypophosphatemia (XLH)
Prof Raja Padidela
Manchester, UK
Biagio Palmisano
Rome, Italy
Mon 12
11:50:30
P132
Poster pitching
Anti-RANKL treatment in a murine model of fibrous dysplasia
Biagio Palmisano
Rome, Italy
Garath Penman
Sheffield, UK
Mon 12
11:44:30
P054
Poster pitching
The influence of immune dysregulation on bone metabolism in children with inflammatory bowel disease: the potential for bone as a secondary lymphoid organ
Garath Penman
Sheffield, UK
Ann Prentice
Cambridge, UK
Sun 11
16:10
OC9
Oral communications: Epidemiology and Nutrition
Calcium carbonate supplementation of pregnant rural Gambian mothers alters offspring IGF-1 at age 7.5 years in a sex-dependent manner
Ann Prentice
Cambridge, UK
Mary Ramnitz
Bethesda, USA
Tue 13
10:30
OC20
Oral communications: Miscellaneous
Autoimmune hyperphosphatemic tumoral calcinosis
Mary Ramnitz
Bethesda, USA
Frank Rauch
Montreal, Canada
Sun 11
09:30
IS02
What is new: 2 years in review
Highlights in clinical bone research
Frank Rauch
Montreal, Canada
Sun 11
Charles Slemenda Award
Charles Slemenda Award
Frank Rauch
Montreal, Canada
Christine Rodda
Melbourne, Australia
Sun 11
11:47:30
P065
Poster Pitching
A novel form of congenital rickets due to a recurrent gain of function mutation in CYP3A4
Christine Rodda
Melbourne, Australia
Maria Rønne
Odense, Denmark
Mon 12
11:40
P004
Poster pitching
Bone mass tracks into teenage years
Maria Rønne
Odense, Denmark
Michela Rossi
Melbourne, Australia
Mon 12
11:43
P034
Poster pitching
Identification of bone remodelling alterations in Gorham-Stout disease
Michela Rossi
Melbourne, Australia
Dr. Anya Rothenbuhler
Paris, France
Tue 13
11:50
IS19
Signalling pathways and their significance for bone health and disease (concurrently with Allied Health Professionals session)
Signalling pathways and their significance for bone health and disease. PTH/cAMP/PKA
Dr. Anya Rothenbuhler
Paris, France
Frank Rutsch
Münster, Germany
Mon 12
10:00
IS10
Genetics and Epigenetics: The impact for rare bone diseases
Arterial calcification syndromes: causes and treatments
Frank Rutsch
Münster, Germany
Peter Simm
Melbourne, Australia
Mon 12
11:47:30
P102
Poster pitching
Do measures of adiposity and muscle cross-sectionally predict the health of weight-bearing bones in 11-12 year old Australian children? A population-based study
Peter Simm
Melbourne, Australia
Taryn Smith
Guildford, Surrey
Sun 11
16:20
OC10
Oral communications: Epidemiology and Nutrition
Inadequate vitamin D status adversely affects trabecular bone mineral density in 14-18 year old adolescents
Taryn Smith
Guildford, Surrey
Sonja Soininen
Kuopio, Finland
Mon 12
11:30
OC14
Oral communications: Muscle and bone mineral density
Body composition and associated biomarkers as determinants of bone mineral density in children 6-8 years of age - the Physical Activity and Nutrition in Children (PANIC) study
Sonja Soininen
Kuopio, Finland
Bonny Specker
South Dakota, USA
Tue 13
09:00
IS16
Nutrition and bone health
Body composition and physical activity
Bonny Specker
South Dakota, USA
Josephine Tauer
Montreal, Canada
Tue 13
14:55
LB1
Oral communications: Hot topics
Treatment with a novel activin receptor IIB ligand trap improves muscle mass and bone geometry in a mouse model of severe osteogenesis imperfecta
Josephine Tauer
Montreal, Canada
Valérie Trichet
Nantes, France
Tue 13
10:20
OC19
Oral communications: Miscellaneous
Mesenchymal stromal stem cells in pediatric orthopedic oncology, focus on osteosarcoma
Valérie Trichet
Nantes, France
Enrica Urciuoli
Rome, Italy
Mon 12
11:55
P202
Poster pitching
Osteosarcoma-derived extracellular vesicles induce tumoral-like phenotypes in normal cells
Enrica Urciuoli
Rome, Italy
Sarah Valkama
Helsinki, Finland
Tue 13
11:37
P020
Allied health professionals session (concurrently with signaling pathways symposium)
Age at onset of walking affects bone mineral content in early childhood
Sarah Valkama
Helsinki, Finland
Dimitris Vlachopoulos
Exeter, UK
Sun 11
11:40
P013
Poster Pitching
Longitudinal evaluation of bone mass, geometry and metabolism in adolescent male athletes. The PRO-BONE study
Dimitris Vlachopoulos
Exeter, UK
Marius Vogt
Würzburg, Germany
Mon 12
15:10
OC16
Oral communications: Bone fragility and metabolism
Pediatric hypophosphatasia – a retrospective single-center chart review of 50 children
Marius Vogt
Würzburg, Germany
Leanne Ward
Ontario , Canada
Sat 10
Workshop: Osteogenesis imperfecta
What does the future hold
Leanne Ward
Ontario , Canada
Leanna Ward
Ottawa, Canada
Mon 12
16:00
IS13
Chronic disease and bone
Osteoporosis in boys with Duchenne Muscular Dystrophy: morbidity, mechanisms and the path forward
Leanna Ward
Ottawa, Canada
Kate Ward
Southampton, UK
Tue 13
Meet the expert
From bench to bedside: Looking at the use of HR CT and QCT in a diagnostic setting
Kate Ward
Southampton, UK
Hope Weiler
Ottawa, Canada
Mon 12
11:52
P142
Poster pitching
Walking within 12 months of age is related to higher whole body lean mass and bone mineral density in children at 3 years of age
Hope Weiler
Ottawa, Canada
Bettina Willie
Montreal, Canada
Sun 11
17:00
IS06
Muscle and bone
The mechanobiology of the growing skeleton
Bettina Willie
Montreal, Canada
Jarod Wong
Glasgow, UK
Mon 12
11:10
OC12
Oral communications: Muscle and bone mineral density
Fracture incident rate and growth in a nationwide cohort of boys with Duchenne muscular dystrophy
Jarod Wong
Glasgow, UK
Margaret Zacharin
Mon 12
11:41:30
P030
Poster pitching
Outcomes of zoledronic acid use in paediatric conditions
Margaret Zacharin
Workshop
2
Sat 10
16:30
Workshop: Osteogenesis imperfecta
Sat 10
Workshop: Osteogenesis imperfecta
Introduction
Christine Burren
UK
Sat 10
Workshop: Osteogenesis imperfecta
Current approaches to treatment
Outi Mäkitie
Helsinki, Finland
Sat 10
Workshop: Osteogenesis imperfecta
What does the future hold
Leanne Ward
Ontario , Canada
Mon 12
17:30
Workshop: Novel perspectives in two rare bone disorders
Oral
6
Sun 11
11:00
Oral communications: Genetics
Sun 11
11:00
OC1
Oral communications: Genetics
NBAS variants causing a novel form of inherited bone fragility
Meena Balasubramanian
Sheffield, UK
Sun 11
11:10
OC2
Oral communications: Genetics
Methylation patterns at the novel DMR of GNAS (GNAS-AS2) in pseudohypoparathyroidism 1B (PHP1B or iPPSD3) subtypes
Agnès Linglart, MD, PhD
Paris, France
Sun 11
11:20
OC3
Oral communications: Genetics
Principal component-derived bone density phenotypes and genetic regulation of the pediatric skeleton
Jonathan Mitchell
Philadelphia, USA
Sun 11
11:30
OC4
Oral communications: Genetics
25-hydroxyvitamin D response to antenatal cholecalciferol supplementation is associated with common vitamin D related genetic variants: findings from the MAVIDOS trial
Rebecca Moon
Southampton, UK
Sun 11
15:30
Oral communications: Epidemiology and Nutrition
Sun 11
15:30
OC5
Oral communications: Epidemiology and Nutrition
Eight-year longitudinal analysis of physical activity and bone strength during adolescence: the Iowa Bone Development Study
Kathleen Janz
Iowa City, USA
Sun 11
15:40
OC6
Oral communications: Epidemiology and Nutrition
Lean mass accretion increases during summer and positively associates with vitamin D status in healthy children 2-8 years
Neil Brett
Montreal, Canada
Sun 11
15:50
OC7
Oral communications: Epidemiology and Nutrition
The effect of antenatal iron supplementation on fibroblast growth factor-23 concentration in mothers and infants: a randomised controlled trial in rural Kenya
Vickie Braithwaite
Cambridge, UK
Sun 11
16:00
OC8
Oral communications: Epidemiology and Nutrition
Effective therapeutic control of curve progression using calcium and vitamin D supplementation for adolescent idiopathic scoliosis – a randomized double-blinded placebo-controlled trial
Tsz Lam
Hong Kong, Hong Kong
Sun 11
16:10
OC9
Oral communications: Epidemiology and Nutrition
Calcium carbonate supplementation of pregnant rural Gambian mothers alters offspring IGF-1 at age 7.5 years in a sex-dependent manner
Ann Prentice
Cambridge, UK
Sun 11
16:20
OC10
Oral communications: Epidemiology and Nutrition
Inadequate vitamin D status adversely affects trabecular bone mineral density in 14-18 year old adolescents
Taryn Smith
Guildford, Surrey
Mon 12
11:00
Oral communications: Muscle and bone mineral density
Mon 12
11:00
OC11
Oral communications: Muscle and bone mineral density
The effect of whole body vibration training on bone and muscle function in children with osteogenesis imperfecta and limited mobility: a randomized controlled pilot trial
Wolfgang Högler
Linz, Austria
Mon 12
11:10
OC12
Oral communications: Muscle and bone mineral density
Fracture incident rate and growth in a nationwide cohort of boys with Duchenne muscular dystrophy
Jarod Wong
Glasgow, UK
Mon 12
11:20
OC13
Oral communications: Muscle and bone mineral density
Enterococccus faecium abundance in gut microbiome is associated with higher bone mineral density in school age children
Carolina Medina-Gomez
Rotterdam, Netherlands
Mon 12
11:30
OC14
Oral communications: Muscle and bone mineral density
Body composition and associated biomarkers as determinants of bone mineral density in children 6-8 years of age - the Physical Activity and Nutrition in Children (PANIC) study
Sonja Soininen
Kuopio, Finland
Mon 12
15:00
Oral communications: Bone fragility and metabolism
Mon 12
15:00
OC15
Oral communications: Bone fragility and metabolism
Fractures in school age children in relation to sex, ethnic background and bone mineral density: the Generation R study
Olja Grgic
Rotterdam, Netherlands
Mon 12
15:10
OC16
Oral communications: Bone fragility and metabolism
Pediatric hypophosphatasia – a retrospective single-center chart review of 50 children
Marius Vogt
Würzburg, Germany
Mon 12
15:20
OC17
Oral communications: Bone fragility and metabolism
Vertebral fractures in children with chronic inflammatory and/or disabling conditions: the SNAP study
Nicola Crabtree
Birmingham, UK
Tue 13
10:10
Oral communications: Miscellaneous
Tue 13
10:10
OC18
Oral communications: Miscellaneous
Stimulation of angiogenesis and osteogenesis by enhanced preosteoclast platelet derived growth factor type BB attenuates glucocorticoid-induced osteoporosis in growing mice
Janet Crane
Baltimore, USA
Tue 13
10:20
OC19
Oral communications: Miscellaneous
Mesenchymal stromal stem cells in pediatric orthopedic oncology, focus on osteosarcoma
Valérie Trichet
Nantes, France
Tue 13
10:30
OC20
Oral communications: Miscellaneous
Autoimmune hyperphosphatemic tumoral calcinosis
Mary Ramnitz
Bethesda, USA
Tue 13
10:40
OC21
Oral communications: Miscellaneous
Scoliosis in fibrous dysplasia/McCune-Albright syndrome
Alison Boyce
Bethesda, USA
Tue 13
10:50
OC22
Oral communications: Miscellaneous
Type I collagen C-propeptide cleavage deficiency increases bone mineralization and alters bone cell differentiation
Joan Marini
Bethesda, USA
Tue 13
14:15
Oral communications: Hot topics
Tue 13
14:15
OC23
Oral communications: Hot topics
Sustained radiographic and functional improvements with asfotase alfa treatment from up to 7 years in children with hypophosphatasia
Scott Moseley
Indianapolis, USA
Tue 13
14:25
OC24
Oral communications: Hot topics
KRN23 effects on phosphate and vitamin D dysregulation in children <5 years old with x-linked hypophosphatemia (XLH)
Erik Imel
Indianapolis, USA
Tue 13
14:35
OC25
Oral communications: Hot topics
Biochemical and physical function outcomes after 5 years of treatment with asfotase alfa in adolescents and adults with hypophosphatasia: phase 2 study results
Scott Moseley
Indianapolis, USA
Tue 13
14:45
OC26
Oral communications: Hot topics
A randomized, open-label phase 2 study of KRN23, an investigational fully human anti-FGF23 monoclonal antibody, in children with x-linked hypophosphatemia (XLH)
Prof Raja Padidela
Manchester, UK
Tue 13
14:55
LB1
Oral communications: Hot topics
Treatment with a novel activin receptor IIB ligand trap improves muscle mass and bone geometry in a mouse model of severe osteogenesis imperfecta
Josephine Tauer
Montreal, Canada
Expert
3
Sun 11
08:00
Meet the expert
Sun 11
Meet the expert
Prevention of rickets and osteomalacia - why, how?
Wolfgang Högler
Linz, Austria
Mon 12
08:00
Meet the expert
Mon 12
Meet the expert
The genetic basis of bone disorders- what every clinician needs to know
Outi Mäkitie
Helsinki, Finland
Mon 12
Meet the expert
Bone pain: mechanisms and intervention
Jacqui Clinch
Bath, UK
Mon 12
Meet the expert
DEXA – how, when and what?
Nicola Crabtree
Birmingham, UK
Tue 13
08:00
Meet the expert
Tue 13
Meet the expert
Recurrent fractures in childhood – causes, investigations and management
Nick Bishop
Sheffield, UK
Tue 13
Meet the expert
From bench to bedside: Looking at the use of HR CT and QCT in a diagnostic setting
Kate Ward
Southampton, UK
Tue 13
Meet the expert
Managing hypercalcemia in neonates/infants
Agnès Linglart, MD, PhD
Paris, France
Plenary
0
Catering and Social
2
Sun 11
10:30
Charles Slemenda Award
Sun 11
Charles Slemenda Award
Charles Slemenda Award
Frank Rauch
Montreal, Canada
Tue 13
15:10
Presentation of awards
Nurse
9
Sun 11
09:00
What is new: 2 years in review
Sun 11
09:00
IS01
What is new: 2 years in review
Highlights in basic bone research
Roland Baron
Boston, USA
Sun 11
09:30
IS02
What is new: 2 years in review
Highlights in clinical bone research
Frank Rauch
Montreal, Canada
Sun 11
14:00
Basic bone biology: osteoblasts, osteocytes, microstructure
Sun 11
14:00
IS03
Basic bone biology: osteoblasts, osteocytes, microstructure
Bone cells in health and disease
Antonella Forlino
Pavia, Italy
Sun 11
14:30
IS04
Basic bone biology: osteoblasts, osteocytes, microstructure
Cortical bone structure and material properties
Björn Busse
Hamburg, Germany
Sun 11
15:00
IS05
Basic bone biology: osteoblasts, osteocytes, microstructure
Skeletal mineralization – enzymes and animal models
José Millán
La Jolla, USA
Sun 11
17:00
Muscle and bone
Sun 11
17:00
IS06
Muscle and bone
The mechanobiology of the growing skeleton
Bettina Willie
Montreal, Canada
Sun 11
17:30
IS07
Muscle and bone
A role for leptin as a myokine mediating muscle-bone interactions
Mark Hamrick
Atlanta, USA
Mon 12
09:00
Genetics and Epigenetics: The impact for rare bone diseases
Mon 12
09:00
IS08
Genetics and Epigenetics: The impact for rare bone diseases
Next generation sequencing and genome editing, game changers in the field of skeletal research
Uwe Kornak
Berlin, Germany
Mon 12
09:30
IS09
Genetics and Epigenetics: The impact for rare bone diseases
Skeletal dysplasias
Melita Irving
London, UK
Mon 12
10:00
IS10
Genetics and Epigenetics: The impact for rare bone diseases
Arterial calcification syndromes: causes and treatments
Frank Rutsch
Münster, Germany
Mon 12
14:00
Rare bone diseases
Mon 12
14:00
IS11
Rare bone diseases
Overview: why study rare bone diseases?
Hans Leeuwen
Rotterdam, Netherlands
Mon 12
14:30
IS12
Rare bone diseases
The ERNS as a tool for the European research on rare diseases
Kassim Javaid
Oxford, UK
Mon 12
16:00
Chronic disease and bone
Mon 12
16:00
IS13
Chronic disease and bone
Osteoporosis in boys with Duchenne Muscular Dystrophy: morbidity, mechanisms and the path forward
Leanna Ward
Ottawa, Canada
Mon 12
16:30
IS14
Chronic disease and bone
Bone, body composition and metabolic abnormalities after allogeneic hematopoietic stem cell transplantation during childhood
Sogol Mostoufi-Moab
Philadelphia, USA
Mon 12
17:00
IS15
Chronic disease and bone
An integrated approach to kidney bone disease across the spectrum
Craig Langman
Chicago, USA
Tue 13
09:00
Nutrition and bone health
Tue 13
09:00
IS16
Nutrition and bone health
Body composition and physical activity
Bonny Specker
South Dakota, USA
Tue 13
09:30
IS17
Nutrition and bone health
Factors influencing peak bone mass
Nick Harvey
Tue 13
11:30
Signalling pathways and their significance for bone health and disease (concurrently with Allied Health Professionals session)
Tue 13
11:30
IS18
Signalling pathways and their significance for bone health and disease (concurrently with Allied Health Professionals session)
Phosphate and FGF23 signalling
Justine Bacchetta
Lyons, France
Tue 13
11:50
IS19
Signalling pathways and their significance for bone health and disease (concurrently with Allied Health Professionals session)
Signalling pathways and their significance for bone health and disease. PTH/cAMP/PKA
Dr. Anya Rothenbuhler
Paris, France
Tue 13
12:10
IS20
Signalling pathways and their significance for bone health and disease (concurrently with Allied Health Professionals session)
Canonical Wnt signaling in bone health and disease
Wim Hul
Antwerp, Belgium
Tue 13
13:10
Treating children’s bones: present and future
Tue 13
13:10
IS21
Treating children’s bones: present and future
BOOSTB4: Boost Brittle Bones Before Birth, A clinical trial on pre- and/or postnatal stemm cell transplantation for treatment of osteogenesis imperfecta
Cecilia Götherström
Huddinge, Sweden
Tue 13
13:40
IS22
Treating children’s bones: present and future
Role of microRNAs in the development of osteosarcoma
Eric Hesse
Huddinge, Sweden
Other
3
Sun 11
11:40
Poster Pitching
Sun 11
11:40
P013
Poster Pitching
Longitudinal evaluation of bone mass, geometry and metabolism in adolescent male athletes. The PRO-BONE study
Dimitris Vlachopoulos
Exeter, UK
Sun 11
11:41:30
P019
Poster Pitching
Zebrafish as model organism for craniosynostosis
Rabea Bleumel
Würzburg, Germany
Sun 11
11:44:30
P027
Poster Pitching
Sex and iron modify fibroblast growth factor 23 concentrations in 1-year-old children
Elisa Holmlund-Suila
Helsinki, Finland
Sun 11
11:46
P039
Poster Pitching
Cystinosin deficiency affects bone phenotype
Giulia Battafarano
Rome, Italy
Sun 11
11:47:30
P065
Poster Pitching
A novel form of congenital rickets due to a recurrent gain of function mutation in CYP3A4
Christine Rodda
Melbourne, Australia
Sun 11
11:49
P079
Poster Pitching
Assessment of a semi-automated software program for the identification of vertebral fractures in children
Fawaz Alqahtani
Lucknow, India
Sun 11
11:50:30
P125
Poster Pitching
Identification and characterization of a novel microRNA inhibiting osteoblast functions by suppressing actin polymerization
Aljaz John
Lucknow, India
Sun 11
11:52
P141
Poster Pitching
Unique correlation pattern between cortical trabecular bone qualities and standard dynamometer handgrip strength in girls with adolescent idiopathic scoliosis (AIS)?
Ka-Yee Cheuk
Shatin, Hong Kong
Sun 11
11:53:30
P161
Poster Pitching
Early-life vitamin D status and bone mass at five years in a prospective birth cohort study
Carol Chaomh
Cork, Ireland
Sun 11
11:55
P189
Poster Pitching
A deep phenotyping of autosomal dominant osteopetrosis type 2 (ADO2) mouse model revealed multiorgan dysfunctions
Antonio Maurizi
Mon 12
11:40
Poster pitching
Mon 12
11:40
P004
Poster pitching
Bone mass tracks into teenage years
Maria Rønne
Odense, Denmark
Mon 12
11:41:30
P030
Poster pitching
Outcomes of zoledronic acid use in paediatric conditions
Margaret Zacharin
Mon 12
11:43
P034
Poster pitching
Identification of bone remodelling alterations in Gorham-Stout disease
Michela Rossi
Melbourne, Australia
Mon 12
11:44:30
P054
Poster pitching
The influence of immune dysregulation on bone metabolism in children with inflammatory bowel disease: the potential for bone as a secondary lymphoid organ
Garath Penman
Sheffield, UK
Mon 12
11:46
P080
Poster pitching
Bone age assessment using Greulich and Pyle and Tanner-Whitehouse methods: a systematic review
Khalaf Alshamrani
Sheffield, UK
Mon 12
11:47:30
P102
Poster pitching
Do measures of adiposity and muscle cross-sectionally predict the health of weight-bearing bones in 11-12 year old Australian children? A population-based study
Peter Simm
Melbourne, Australia
Mon 12
11:49
P114
Poster pitching
Rare copy number variants in array-based comparative genomic hybridization in early-onset skeletal fragility
Alice Costantini
Stockholm, Sweden
Mon 12
11:50:30
P132
Poster pitching
Anti-RANKL treatment in a murine model of fibrous dysplasia
Biagio Palmisano
Rome, Italy
Mon 12
11:52
P142
Poster pitching
Walking within 12 months of age is related to higher whole body lean mass and bone mineral density in children at 3 years of age
Hope Weiler
Ottawa, Canada
Mon 12
11:53:30
P182
Poster pitching
Osteonecrosis results in significant long term morbidity in patients with acute lymphoblastic leukaemia
Nadia Amin
Leeds Teaching Hospital, Leeds, UK
Mon 12
11:55
P202
Poster pitching
Osteosarcoma-derived extracellular vesicles induce tumoral-like phenotypes in normal cells
Enrica Urciuoli
Rome, Italy
Tue 13
11:30
Allied health professionals session (concurrently with signaling pathways symposium)
Tue 13
11:30
P097
Allied health professionals session (concurrently with signaling pathways symposium)
Evaluation of the use of body quantitative computed tomography for the assessment of the tibia in children with neurofibromatosis 1
Alex Ireland
Manchester, UK
Tue 13
11:37
P020
Allied health professionals session (concurrently with signaling pathways symposium)
Age at onset of walking affects bone mineral content in early childhood
Sarah Valkama
Helsinki, Finland
Tue 13
11:44
P007
Allied health professionals session (concurrently with signaling pathways symposium)
Effects of a 8-month physical activity and nutrition-induced weight loss program on bone health of obese adolescents
Elodie Chaplais
Aubiere, France
Tue 13
11:51
P101
Allied health professionals session (concurrently with signaling pathways symposium)
Establishing the clinical need for a dedicated service for children and adolescents with osteogenesis imperfecta in the Republic of Ireland
Ciara McDonnell
Dublin, Ireland
Tue 13
11:58
P204
Allied health professionals session (concurrently with signaling pathways symposium)
Is a modified version of the Childhood Health Assessment Questionnaire (CHAQ) a useful tool to identify the level of disability in children with osteogenesis imperfecta?
Suzanne Bell
Birmingham, UK
Tue 13
12:05
P208
Allied health professionals session (concurrently with signaling pathways symposium)
Social barriers and needs of children with osteogenesis imperfecta (OI): a qualitative descriptive interview-based study
Jerzy Konstantynowicz
Bialystok, Poland
Symposium
3
Sat 10
14:50
Children's bones in health and disease
Sat 10
Children's bones in health and disease
Bone Fraglity
Outi Mäkitie
Helsinki, Finland
Sat 10
Children's bones in health and disease
Bone Mineralisation
Keiichi Ozono
Suita, Japan
Sat 10
Children's bones in health and disease
Bone Dyspasia
Melita Irving
London, UK
Sat 10
Children's bones in health and disease
Abnormality of calcium and phosphate homeostasis
Agnès Linglart, MD, PhD
Paris, France
Sat 10
18:00
Satellite symposium: Novel insights into the broad clinical manifestations and management of XLH
Sun 11
18:15
Satellie symposium: Hypophosphatasia in children: strengthening the foundations for managing a complex disease
No Session Type
9
Sat 10
07:30
Registration
Sat 10
12:30
Networking session
Sat 10
17:30
Welcome Address
Sun 11
07:30
Registration
Sun 11
08:00
Meet the expert
Sun 11
Meet the expert
Physical activity to improve bone stability
Sun 11
08:00
Meet the expert
Sun 11
Meet the expert
Molecular mechanisms of disorders with abnormal bone mass and fragility
Uwe Kornak
Berlin, Germany
Mon 12
07:30
Registration
Tue 13
07:30
Registration
Tue 13
15:25
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