Genetic models of pituitary disease in MEN1

Modelling pituitary tumours in zebrafish

Mouse model of craniopharyngioma

Molecular signatures of pituitary tumours

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ER stress and metabolic regulation

ER stress, leptin signalling and obesity

Lipotoxic endoplasmic reticulum stress and pancreatic beta-cell demise in type 2 diabetes

Patients with monogenic diabetes resulting from ER stress of the pancreatic beta-cell

Is there a male menopause - lesson from the European Male Ageing Study

Does testosterone treatment increase mortality in elderly men?

What is the best form of testosterone replacement?

Can testosterone therapy be stopped in some hypogonadal patients?

Magnetic nanoparticles for drug delivery

Nanoparticles as imaging agents

Nanomedicine in clinical diabetes

Functional characterisation and translational clinical applications of kisspeptin-10

Structure-function analysis of calcium-sensing receptor (CaSR) mutations reveal clustering at calcium binding sites of the extracellular bilobed venus flytrap domain

Effect of selenium status on the skeleton in post-menopausal women: the OPUS study

The thyroid hormone receptor-coactivator interface mediates negative feedback regulation of the human pituitary-thyroid axis

Growth retardation and severe constipation due to the first human, dominant negative thyroid hormone receptor alpha mutation

A homozygous glutathione peroxidase 1 mutation, p.Arg130-Leu133del, in a patient with familial glucocorticoid deficiency

Progressive adrenal insufficiency and 46,XY DSD caused by two novel mutations in the cytochrome P450 side-chain cleavage (CYP11A1) gene

Metastasis related methyltransferase 1 (Merm1)/WBSCR22 regulates glucocorticoid receptor (GR) function

Can imaging predict malignancy in a thyroid nodule?

Predictive value of cytology and molecular markers in thyroid cancer

The place of radioiodine in the management of thyroid cancer

Novel treatments - from PCR to patient

The expression of kisspeptin and kisspeptin receptor is altered in pre-eclampsia

Contrasting effects of kisspeptin-10 between men and women reveal sexual dimorphism in the hypothalamic regulation of human reproduction

Kissorphin, a hexapeptide derivative of kisspeptin, acts via neuropeptide FF receptors to inhibit cyclic adenosine monophosphate release but has no gonadotrophin-releasing hormone releasing activity

ERβ and GPR30 mediate distinct and opposite oestrogenic influences on microglial phagocytosis of apoptotic neuronal cells

Nutrient regulation of growth factor signalling in human placenta

Identification of microRNAs involved in regulating growth factor signalling in the first trimester placenta

Increased cardiovascular events in women with polycystic ovary syndrome: retrospective analysis of a large database

A calcium-sensing receptor (CaSR) variant, Glu250Lys, present in familial hypocalciuric hypercalcaemia (FHH) and autosomal dominant hypocalcaemic hypercalciuria (ADHH) probands represents a functionally neutral polymorphism: lessons for CaSR mutational analysis

Muscles and their myokines

Exercise effects on fat metabolism and insulin sensitivity in human muscle

Novel signalling mechanisms controlling glycogen homeostasis in muscle

Mitochondrial dysfunction and muscle disease

The follow up of cancer survivors

The impact of cancer treatment on pituitary function

The impact of cancer treatment on fertility and pregnancy

The late consequences of cancer therapy to the thyroid

Challenging the dogma: Tissue specific regulation of insulin action

Quantifying in vivo extra-adrenal cortisol production and dysregulation in human metabolic disease

Therapeutic management of adults with CAH

Amiodarone

Preventing and managing long term complications of acromegaly

Ageing gracefully - the role of 11beta-HSD1

Old drugs for new targets - CYP11B2 inhibitors for hypertension

Dual aromatase and steroid sulfatase inhibition in breast cancer

Potential prostate cancer drug target: bioactivation of androstanediol by conversion to dihydrotestosterone

Metformin in obese children and adolescents (MOCA) trial

Post-prandial high fat intake leads to acute exposure to circulating endotoxin in type 2 diabetes mellitus subjects

Risk of diabetes, cancer, large vessel disease and mortality in young women with polycystic ovary syndrome: a retrospective databased analysis

Glucose absorption capacity of the mature adipose tissue is increased after Bardet-Biedl syndrome induced ciliary defect in adipocytes' precursors

Steroidogenic function following B lymphocyte depletion therapy in new onset autoimmune Addison's disease

GATA3 polymorphisms are associated with autoimmune Addison's disease

Subclinical hypothyroidism is associated with fatigue and impaired functional status in males in the Whickham 20-year follow up cohort

Dietary factors augment the ability of the proto-oncogene PBF to induce goitrogenesis and hyperplasia in vivo

Impact of lifestyle choices on skeletal health

Osteoporosis and metabolic bone disease in adolescence

Complications of antiresorptive agents

New and emerging therapies for osteoporosis

Estrogen receptor insensitivity: physiological and clinical consequences

Bone as endocrine organ

Increased 11β-hydroxysteroid dehydrogenase type 1 activity is associated with the adverse expression of glucocorticoid target genes in ageing human skin

Age-dependent increase in the expression/activity of 11β-HSD1 in key metabolic tissues may underpin the ageing phenotype, notably sarcopenia

A hypomorphic H6PD allele is sufficient to rescue the skeletal myopathy but not the lack of 11β-HSd type-1 mediated glucocorticoid regeneration phenotypes of H6PDKO mice

Broad phenotypic spectrum of 17a-hydroxylase deficiency: functional characterisation of 4 novel mutations in the CYP17A1 gene

A novel repressor mechanism regulating fetal Leydig cell steroidogenesis, pertubation of which results in masculinization disorders

Fatty liver in a mouse model of congenital adrenal hyperplasia is driven by peroxisome proliferator-activated receptors

Glucocorticoids increase subcutaneous adipose tissue insulin sensitivity in vivo: a randomised double-blind, placebo controlled, cross over study

The role of a novel co-regulator in modifying the transcriptional activities of the glucocorticoid receptor

The origins and evolution of lactase persistence

Melatonin, light and sleep in the Antartic

Cortisol and mood - coping with seasons

Resurgence of vitamin D deficiency rickets in the UK

Obtaining fellowship funding and networking

Pathways in clinical academia, fellowships and networking

Career opportunities in the States

Trials and tribulations of the university lecturer

Therapeutic management of adults with CAH

Human growth is regulated by an ubiquitination pathway including CUL7, OBSL1 and CCDC8

A network analysis of gene expression through childhood highlights changes related to age and growth

Long term experience of 131I-MIBG therapy in the treatment of neuroendocrine tumours: has it improved survival and what are the long term sequelae?

Steroid metabolomics in adrenocortical carcinoma reveal mitotane as an inducer of CYP3A4 and an inhibitor of 5alpha-reductase activity with major implications for drug metabolism and hydrocortisone replacement

Role of the hypoxic signalling pathways in the histopathological prediction of malignancy in phaeochromocytomas and paragangliomas

SUMOylation genes in pituitary gonadotrophs: wrestling with GnRH signalling

The role of the familialpituitary adenoma gene, AIP, in the proliferative and invasive activity of a malignant pancreatic cell line

Control of GH and IGF1 in acromegaly in the UK: responses to medical treatment

MicroRNA: an introduction

MicroRNA regulation of the IGF axis

MicroRNA and the beta-cell

MicroRNA in the diagnosis and therapy of endcorine cancers

Amiodarone

Metabolism to epigenetics: the circadian clock link

Management of persistent TSH elevation in hypothyroid patients

The surgical approaches to MEN1 - what the endocrinologist needs to know

Developmental programming of type 2 diabetes

Neuroendocrine origins of obesity

The foetus or the placenta? Targets of glucorticoid programming

Obesity in pregnancy: implications for the next generation

Genetics and epidemiology

Molecular mechanisms of phaeochromocytoma and tumorigenesis

Laboratory assessment and diagnostic imaging

Novel therapies for malignant phaeochromocytomas and paragangliomas

Thyroid Eye Disease - presentation and treatment

Thyroid Eye Disease

Thyroid Eye Disease

GLP-1 therapy of type 2 diabetes - current status

Acromegaly - improving outcomes

A difficult TASK: murine models of mineralocorticoid excess

Human potassium channel mutations and mineralocorticoid hypertension

Long term consequences of primary hyperaldosteronism

Therapeutic options for mineralocorticoid hypertension

Molecular pathogenesis of MTC

RAS mutations in sporadic MTC

The diagnosis and management of MTC

Novel targeted therapies for MTC

Conn's and phaeochromocytoma

Nursing case study on phaeochromocytoma

Introduction to Addison's

Day-to-day practice on management of steroid replacement

Living with Addison's

Optogenetics: controlling cells with light

All you need to know about CHIP-sequencing

Genetic, molecular and physiological mechanisms involved in human obesity

The thyroid - too much and too little across the ages

Hyponatraemia in neurosurgical patients: insights and implications

Accelerating post-aneurysm recovery by correcting hypotraemia

Prioritising therapy in neuroendocrine tumours

Regulating periods and optimising fertility in PCOS

Developing growth hormone agonists and antagonists for the clinic

Long-term outcome and quality of life in patients with disorders of sex development

Opportunities in translational research - the NIHR/MRC Efficacy and Mechanisms Evaluations (EME) Board

NIHR research networks: an update

Seeing the light

It's time to identify the hormone that maintains bodty fat content

UK stance on adult GH replacment maintains our isolation from Europe

Assisted conception and developing low cost version for the developing world

Tales from an arthritic endocrinologist - why does the endocrine dog not bark in the cytokine night?

Psychopathology of false conviction

Novel mutations causing infertility

Semen analysis: what does it mean and can we improve it?

How can we predict ovarian reserve and how useful is this?

The endocrine basis of what we do in the IVF clinic

Drug-induced hyperprolactinaemia

Endocrine assessment in HIV/AIDS

Neuroendocrine assessment in morbid obesity

Endocrine evaluation in a patient with coeliac disease

Hypogonadism in a man with cancer of the prostate

Endocrine evaluation in a patient with iron overload

The surgical approaches to MEN1 - what the endocrinologist needs to know

Management of persistent TSH elevation in hypothyroid patients

Preventing and managing long term complications of acromegaly

Regulating periods and optimising fertility in PCOS

Prioritising therapy in neuroendocrine tumours