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Mon 18 Mar 2013
Mon 18
Tue 19 Mar 2013
Tue 19
Wed 20 Mar 2013
Wed 20
Thu 21 Mar 2013
Thu 21
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Monday 18 March
17 sessions
09:00 - 13:00
REGISTRATION
RECEPTION AREA
11:00 - 12:30
Symposium 1: Irn Bru, to drink or not to drink: endocrinology and iron
This symposium will introduce the endocrine biology of iron metabolism and disorders of iron excess or insufficiency
MAIN AUDITORIUM
Chairs: D Renshaw (London) & M Zariwala (London)
S1.1
Symposium 1: Irn Bru, to drink or not to drink: endocrinology and iron
Iron homeostasis: who are the major players?
R Evans
La Jolla, USA
S1.2
Symposium 1: Irn Bru, to drink or not to drink: endocrinology and iron
The iron regulatory hormone hepcidin
A Drakesmith
S1.3
Symposium 1: Irn Bru, to drink or not to drink: endocrinology and iron
'The Celtic disease' - haemochromatosis: a disease of iron overload
H Zoller
Innsbruck, Austria
11:00 - 12:30
Symposium 2: Hormones Maketh Man
QUEEN'S SUITE A
Chairs: R Sharpe (Edinburgh) & T Tremaine (London)
S2.1
Symposium 2: Hormones Maketh Man
Anti-müllerian hormone - a Sertoli cell hormone that can be used as a predictor of male hypogonadism
R Rey
Buenos Aires, Argentina
S2.2
Symposium 2: Hormones Maketh Man
The role of the Sertoli cell in driving 'maleness'
S Nef
Geneva, Switzerland
S2.3
Symposium 2: Hormones Maketh Man
Androgens and male fertility - a long way from the black box theory
L Smith
11:00 - 12:30
Symposium 3: Nurture not nature: epigenetics and disease susceptibility
QUEEN'S SUITE B
Chairs: A Clark (London) & K Lines (Oxford)
S3.1
Symposium 3: Nurture not nature: epigenetics and disease susceptibility
Epigenome-wide association studies for common human diseases
V Rakyan
S3.2
Symposium 3: Nurture not nature: epigenetics and disease susceptibility
Nutritional programming of epigenetics in metabolic syndrome
Anne White
Manchester, UK
S3.3
Symposium 3: Nurture not nature: epigenetics and disease susceptibility
Epigenetic differences associated with prenatal exposure to famine in humans
L Lumey
Columbia, USA
12:30 - 13:30
Otsuka satellite symposium:
The hyponatraemic brain and bone: current and future treatment targets
QUEEN'S SUITE A (lunch available in QS foyer)
Chair: R Eastell (Sheffield)
J Verbalis (Georgetown, WA, USA)
12:30 - 13:45
LUNCH
HALL H
13:45 - 15:45
Symposium 4: New Bone Biology - Is there life after RANK ligand?
MAIN AUDITORIUM
Chairs: E McCloskey (Sheffield) & S Orme (Leeds)
S4.1
Symposium 4: New Bone Biology - Is there life after RANK ligand?
New bone biology and Cathepsin K inhibitors
R Eastell
S4.2
Symposium 4: New Bone Biology - Is there life after RANK ligand?
Inhibition of sclerostin in the treatment of osteoporosis
S Papapoulos
Leiden, The Netherlands
S4.3
Symposium 4: New Bone Biology - Is there life after RANK ligand?
Parathyroid hormone related peptide as a potential treatment for osteoporosis
P Esbrit
Madrid, Spain
S4.4
Symposium 4: New Bone Biology - Is there life after RANK ligand?
Organic nitrates for the treatment of postmenopausal osteoporosis
S Jamal
Toronto, Canada
13:45 - 15:45
Oral Communications 1: Young Endocrinologists's Prize Session
QUEEN'S SUITE B
Chairs: R Ross (Sheffield) & S Mirczuk (London)
OC1.1
Oral Communications 1: Young Endocrinologists's Prize Session
TNFα directly regulates in vivo corticosteroid metabolism in inflammatory arthritis
D Nanus
OC1.2
Oral Communications 1: Young Endocrinologists's Prize Session
Macrophage-specific 11β-hydroxysteroid dehydrogenase type 1 deficiency promotes angiogenesis but impairs resolution of K/BxN serum induced arthritis
Z Zhang
OC1.3
Oral Communications 1: Young Endocrinologists's Prize Session
11β-HSD1KO mice are protected from glucocorticoid dependent age-associated muscle atrophy
Z Hassan-Smith
OC1.4
Oral Communications 1: Young Endocrinologists's Prize Session
A Serum MicroRNA Profile Potentially Associated with Glucocorticoid Mediated Insulin Resistance
L Gathercole
OC1.5
Oral Communications 1: Young Endocrinologists's Prize Session
Inhibition of 5α-reductase type 1 with dutasteride impairs insulin sensitivity
R Upreti
OC1.6
Oral Communications 1: Young Endocrinologists's Prize Session
Improving the Vitamin D status of Vitamin D deficient adults is associated with improved mitochondrial oxidative function in skeletal muscle
A Sinha
OC1.7
Oral Communications 1: Young Endocrinologists's Prize Session
Autosomal dominant hypocalcemia type 2 is caused by germline GNA11 gain-of-function mutations
S Howles
OC1.8
Oral Communications 1: Young Endocrinologists's Prize Session
Kisspeptin advances ovulation in healthy women
A Comninos
13:45 - 15:45
Applied Physiology Workshop
Digital copies: exploiting numerical models of biological systems
QUEEN'S SUITE A
Chairs: S Lightman (Bristol) & T Han (London)
APW1.1
Applied Physiology Workshop
Modelling neuroendocrine systems
G Leng
APW1.2
Applied Physiology Workshop
Distinguishing normal, depressive and PTSD cortisol dynamics in humans through mathematical modelling
M Rodriguez-Fernandez
Santa Barbara, USA
APW1.3
Applied Physiology Workshop
Analysis and visualisation of biological networks
T Freeman
APW1.4
Applied Physiology Workshop
Modelling the circulating renin-angiotensin system and its efefcts on blood pressure
P Hannaert
Poitiers, France
15:45 - 16:15
TEA & COFFEE
HALL H
16:15 - 18:15
Clinical Management Workshop 1: Management controversies in parathyroid disease
Supported by Clinical Endocrinology and Hypoparathyroidism UK
HALL D
Chairs: A Abbas (Doncaster) & N Gittoes (Birmingham)
CMW1.1
Clinical Management Workshop 1: Management controversies in parathyroid disease
Hyperparathyroidism in MEN1
M Brandi
Florence, Italy
CMW1.2
Clinical Management Workshop 1: Management controversies in parathyroid disease
Parathyroid hormone, vitamin D and chronic kidney disease
W Fraser
CMW1.3
Clinical Management Workshop 1: Management controversies in parathyroid disease
'Mild hyperparathyroidism' - what determines clinical outcome?
G Leese
CMW1.4
Clinical Management Workshop 1: Management controversies in parathyroid disease
Medical management of parathyroid disease
D Hosking
16:15 - 18:15
Education Workshop 1: Teaching and Learning in Endocrinology
To highlight approaches used in the undergraduate and post-graduate delivery of endocrine teaching in the UK
QUEEN'S SUITE A
Chairs: J Davis (Manchester) & B Jose (Wolverhampton)
EW1.1
Education Workshop 1: Teaching and Learning in Endocrinology
Undergraduate research participation: going beyond 'students as producers'
R Fowkes
EW1.2
Education Workshop 1: Teaching and Learning in Endocrinology
Clinical skills delivery
D Wood
EW1.3
Education Workshop 1: Teaching and Learning in Endocrinology
Recommended standards for undergraduate medical education
M Levy
EW1.4
Education Workshop 1: Teaching and Learning in Endocrinology
Postgraduate training in endocrinolgoy and diabetes - developing the curriculum and assessments
P Selby
16:15 - 18:15
Symposium 5: Sex in the brain
Origins and consequences of sex differences in brain
SUPPORTED BY ENDOCRINE CONNECTIONS
MAIN AUDITORIUM
Chairs: S Lightman (Bristol) & M Rodie (Glasgow)
S5.1
Symposium 5: Sex in the brain
Foetal testosterone in mind
S Baron-Cohen
S5.2
Symposium 5: Sex in the brain
Importance of genomic imprinting in the evolution and development of the maternal brain
E Keverne
S5.3
Symposium 5: Sex in the brain
Neuronal circuits underlying sex specific social behaviour
C Dulac
Cambridge, USA
S5.4
Symposium 5: Sex in the brain
Hormone-dependent chromatin modifications regulating sexually differentiated animal behaviour
D Pfaff
New York, USA
16:15 - 18:15
Oral Communications 2: Steroids and thyroid
QUEEN'S SUITE B
Chairs: R Evans (La Jolla, CA, USA) & X Zou (Edinburgh)
OC2.1
Oral Communications 2: Steroids and thyroid
Loss-of-Function Mutations in IGSF1 Cause a Novel, X-Linked Syndrome of Central Hypothyroidism and Testicular Enlargement
N Schoenmakers
OC2.2
Oral Communications 2: Steroids and thyroid
Abnormal cardiac bio-energetics in subclinical hypothyroidism; cardiac magnetic resonance spectroscopic study
A Madathil
OC2.3
Oral Communications 2: Steroids and thyroid
A bi-transgenic murine model of PTTG and PBF overexpression in the thyroid gland
G Ryan
OC2.4
Oral Communications 2: Steroids and thyroid
THRA or DIO2 mutations are not a common cause of high bone mass in humans
A Gogakos
OC2.5
Oral Communications 2: Steroids and thyroid
A mutation in thioredoxin reductase 2 (TXNRD2) is associated with a predominantly adrenal phenotype in humans
P Prasad
OC2.6
Oral Communications 2: Steroids and thyroid
An N-ethyl-N-nitrosourea induced Corticotrophin releasing hormone (Crh) promoter mutation provides a mouse model of Cushing’s syndrome
L Bentley
OC2.7
Oral Communications 2: Steroids and thyroid
11β-hydroxysteroid dehydrogenase type 1: A role in skin wound healing
A Tiganescu
OC2.8
Oral Communications 2: Steroids and thyroid
When math meets biology: systems approach to drug resistance analysis
D Chen
18:15 - 19:15
Young Endocrinologists Prize Lectures
MAIN AUDITORIUM
Chairs: K Chapman (Edinburgh) & J Franklyn (Birmingham)
YEP1.2
Young Endocrinologists Prize Lectures
Pituitary development: the answer, is blowing in the Wnt
C Gaston-Massuet
YEP1.1
Young Endocrinologists Prize Lectures
Clinical and pre-clinical studies of neuroendocrine tumours (NETs) in Multiple Endocrine Neoplasia type 1 (MEN1), and evaluation of MEN1 gene replacement therapy for MEN1-associated NETs.
G Walls
19:15 - 00:00
Welcome Reception
HALL H
20:00 - 00:00
Young Endocrinologists Quiz
HALL D
Tuesday 19 March
22 sessions
07:00 - 07:15
BREAKFAST
QUEEN'S SUITE FOYER
07:15 - 08:00
Meet the Expert 2
SUPPORTED BY CLINICAL ENDOCRINOLOGY
QUEEN'S SUITE A
Chair: J Wass (Oxford)
MTE2
Meet the Expert 2
Diabetes metellitus, endocrinology and the impact of GP commissioning
G Tan
07:15 - 08:00
Meet the Expert 3
SUPPORTED BY CLINICAL ENDOCRINOLOGY
QUEEN'S SUITE B
Chair: P Stewart (Birmingham)
MTE3
Meet the Expert 3
Investigation of patients with suspected mineralocorticoid hypertension
J Connell
07:15 - 08:00
Meet the Expert 1
Supported by Clinical Endocrinology and the Turner Syndrome Support Society
HALL D
Chairs: H Simpson (Cambridge) & TBC
MTE1
Meet the Expert 1
Turner Syndrome / pregnancy / cardiac risk
G Conway
08:15 - 10:15
Symposium 6: Making the glucocorticoid clock run smoothly
Latest research into diurnal glucocorticoid action
Supported by the Addison’s Disease Self Help Group
QUEEN'S SUITE A
Chairs: M Debono (Sheffield) & W Arlt (Birmingham)
S6.1
Symposium 6: Making the glucocorticoid clock run smoothly
Monitoring glucocorticoid signalling and circadian clock function with transgenic zebrafish reporter lines
T Dickmeis
Karlsruhe, Germany
S6.2
Symposium 6: Making the glucocorticoid clock run smoothly
Molecular dynamics of ultradian glucocorticoid receptor action
B Conway-Campbell
S6.3
Symposium 6: Making the glucocorticoid clock run smoothly
Diurnal cortisol delivery: a novel tool for adrenal insufficiency
R Ross
S6.4
Symposium 6: Making the glucocorticoid clock run smoothly
Retraining the HPA axis: how to cure adrenal insufficiency
S Pearce
Newcastle, UK
08:15 - 10:15
Oral Communications 3: Reproduction, growth and development
QUEEN'S SUITE B
Chairs: U Kaiser (Boston, USA) & O Vaughan (Cambridge)
OC3.1
Oral Communications 3: Reproduction, growth and development
Identification of very early sorting endosomes that spatially program gonadotrophin hormone receptor signalling
F Jean-Alphonse
OC3.2
Oral Communications 3: Reproduction, growth and development
Heterodimerisation of gonadotrophin hormone receptors modifies the LH-induced calcium signalling profile
S Chen
OC3.3
Oral Communications 3: Reproduction, growth and development
Regulation of G protein-coupling specificity via cis and trans activation of the luteinising hormone/chorionic gonadotrophin receptor (LHCGR)
Kim Jonas
London, UK
OC3.4
Oral Communications 3: Reproduction, growth and development
Characterising changes in the in vivo male rodent brain using Magnetic Resonance Spectroscopy
M Rodie
OC3.5
Oral Communications 3: Reproduction, growth and development
Effects of in utero exposure to acetaminophen (paracetamol) on steroidogenesis by the rat and human fetal testis
S Driesche
OC3.6
Oral Communications 3: Reproduction, growth and development
Follistatin-Like 3 (FSTL3), a transforming growth factor β (TGFβ) ligand inhibitor, is essential for placental development in mice.
R Robertson
OC3.7
Oral Communications 3: Reproduction, growth and development
Disruption of Mesenchymal Glucocorticoid Signaling Attenuates Embryonic Lung Development and Results in Post Natal Lethality in Mice
R Hardy
OC3.8
Oral Communications 3: Reproduction, growth and development
Adiponectin induces GSK3 kinase-mediated cross-tolerance to endotoxin in macrophages
L Hand
08:15 - 10:15
Clinical Management Workshop 2: How Do I Do It?
SUPPORTED BY CLINICAL ENDOCRINOLOGY
MAIN AUDITORIUM
Chairs: S Howell (Preston) & C Sze (London)
CMW2.1
Clinical Management Workshop 2: How Do I Do It?
How do I manage testosterone replacement after prostate cancer therapy?
N James
CMW2.2
Clinical Management Workshop 2: How Do I Do It?
How do I investigate and manage hypomagnesaemia?
John Ayuk
Birmingham
CMW2.3
Clinical Management Workshop 2: How Do I Do It?
How do I monitor and follow up transgender patients using hormonal therapies?
L Seal
CMW2.4
Clinical Management Workshop 2: How Do I Do It?
How do I manage the pregnant patient with a prolactinoma?
J Bevan
CMW2.5
Clinical Management Workshop 2: How Do I Do It?
How and when do I induce puberty in males?
I Banerjee
CMW2.6
Clinical Management Workshop 2: How Do I Do It?
How do I - and how should I - induce puberty in females?
M Donaldson
10:15 - 10:40
TEA & COFFEE
HALL H
10:40 - 11:20
SfE Dale Medal Lecture
MAIN AUDITORIUM
Chair: D Ray (Manchester)
PL1
SfE Dale Medal Lecture
Nuclear receptors and AMPK: can exercise mimetics cure diabetes?
R Evans
La Jolla, USA
11:20 - 12:00
SfE Hoffenberg International Medal Lecture
MAIN AUDITORIUM
Chair: G Williams (London)
PL2
SfE Hoffenberg International Medal Lecture
Multiple applications of intracrinology in clinical medicine
F Labrie
Quebec, Canada
12:00 - 14:00
LUNCH & POSTER VIEWING
HALL H
13:00 - 14:00
Ipsen satellite symposium
Achieving biochemical and tumour control in acromegaly and NETs: a focus on optimising dosing of somatostatin analogues
QUEEN'S SUITE A
A Grossman (Oxford)
Ipsen satellite symposium
High-dose lanreotide Autogel for treatment-naive patients with acromegaly: the PRIMARYS trial
J Bevan
Ipsen satellite symposium
Tumour response to presurgical lanreotide Autogel therapy in the ACROPAT trial
M Gurnell
Ipsen satellite symposium
Stabilising tumour growth in patients with NETs
A Grossman
14:00 - 16:00
Oral Communications 4: Obesity, metabolism and bone
QUEEN'S SUITE B
Chairs: R Andrew (Edinburgh) & F Hannan (Oxford)
OC4.1
Oral Communications 4: Obesity, metabolism and bone
Glucocorticoid receptor deficiency in cardiomyocytes causes pathological cardiac remodelling in mice.
R Richardson
OC4.2
Oral Communications 4: Obesity, metabolism and bone
11β-HSD1 Knockout Mice are Protected from the Adverse Metabolic Effects of Exogenous Glucocorticoid Excess
S Morgan
OC4.4
Oral Communications 4: Obesity, metabolism and bone
Cholestatic pregnancy programmes metabolic disease in the offspring
G Papacleovaulou
OC4.3
Oral Communications 4: Obesity, metabolism and bone
Adult offspring of undernourished sheep exhibit epigenetic alterations in HPA axis glucocorticoid receptor
G Begum
OC4.5
Oral Communications 4: Obesity, metabolism and bone
Energy intake following infusion of glucagon and GLP-1: a double-blind crossover study
J Cegia
OC4.6
Oral Communications 4: Obesity, metabolism and bone
Transgenic disruption of 5alpha-reductase1 increases susceptibility to liver fibrosis
D Livingstone
OC4.7
Oral Communications 4: Obesity, metabolism and bone
Familial Hypocalciuric Hypercalcaemia Type 3 (FHH3) is Caused by Mutations in Adaptor Protein 2 Sigma 1 (AP2S1)
A Nesbit
OC4.8
Oral Communications 4: Obesity, metabolism and bone
Peptide YY regulates bone mineral content and strength
14:00 - 16:00
Symposium 7: Thyroid Hormone Receptors - mutations and implications
When TR alpha and beta go bad
SUPPORTED BY JOURNAL OF MOLECULAR ENDOCRINOLOGY
MAIN AUDITORIUM
Chairs: C McCabe (Birmingham) & A Gokakos (London)
S7.1
Symposium 7: Thyroid Hormone Receptors - mutations and implications
Physiologically distinct roles for thyroid hormone receptor isoforms
G Williams
S7.2
Symposium 7: Thyroid Hormone Receptors - mutations and implications
Human thyroid hormone receptor alpha mutations - novel syndrome emerges
S7.3
Symposium 7: Thyroid Hormone Receptors - mutations and implications
Human thyroid hormone receptor beta mutations - syndrome of resistance to thyroid hormone
P Beck-Peccoz
Milan, Italy
S7.4
Symposium 7: Thyroid Hormone Receptors - mutations and implications
Nuclear coregulators confer the actions of mutant thyroid hormone receptor alpha and beta
S-Y Cheng
Bethesda, USA
14:00 - 16:00
YE Symposium: Maintaining your endocrine career despite what life throws at you
Keeping everything up in the air
QUEEN'S SUITE A
Chairs: V Cabrera-Sharp (London) & A Rogers (Oxford)
YE1.1
YE Symposium: Maintaining your endocrine career despite what life throws at you
Maintaining an active basic research career whilst juggling an academic and personal life
G Lavery
YE1.2
YE Symposium: Maintaining your endocrine career despite what life throws at you
Juggling a clinical workload: and academic research
Paul Newey
Dundee, United Kingdom
YE1.3
YE Symposium: Maintaining your endocrine career despite what life throws at you
Getting useful research results from routine NHS activity
T Howlett
YE1.4
YE Symposium: Maintaining your endocrine career despite what life throws at you
Non-traditional career paths towards an acedemic career
P Foster
YE1.5
YE Symposium: Maintaining your endocrine career despite what life throws at you
Re-establishing your research profile after a career break (academic perspective)
K Perry
YE1.6
YE Symposium: Maintaining your endocrine career despite what life throws at you
Putting your best foot forward - what the funders' are looking for
P Saunders
YE Symposium: Maintaining your endocrine career despite what life throws at you
Young Endocrinologists' debate
16:00 - 16:30
TEA & COFFEE
HALL H
16:30 - 17:15
Meet The Expert 4
SUPPORTED BY CLINICAL ENDOCRINOLOGY
HALL D
Chair: R Semple (Cambridge)
MTE4
Meet The Expert 4
Induced plurripotent stem cells as an endocrine tool
N Hanley
16:30 - 18:30
Symposium 8: Non functioning pituitary tumours
Exploring new insights into the natural history, diagnostic markers and management of these common tumours
Supported by Endocrine-Related Cancer and the Pituitary Foundation
QUEEN'S SUITE A
Chairs: A Grossman (Oxford) & A Toogood (Birmingham)
S8.1
Symposium 8: Non functioning pituitary tumours
Epidemiology and natural history of pituitary tumours
Niki Karavitaki
Birmingham, UK
S8.2
Symposium 8: Non functioning pituitary tumours
Pathological mechanisms underlying non-functioning pituitary tumours
M Wierman
Denver, USA
S8.3
Symposium 8: Non functioning pituitary tumours
Pathological markers of aggressive pituitary tumour behaviour - use of MGMT?
M Zatelli
Ferrara, Italy
S8.4
Symposium 8: Non functioning pituitary tumours
Aggressive pituitary tumours and temozolomide treatment
T Brue
Marseille, France
16:30 - 18:30
Oral Communications 5: Pituitary and neoplasia
QUEEN'S SUITE B
Chairs: M Weirman (Denver, CO, USA) & J Bryant (Manchester)
OC5.1
Oral Communications 5: Pituitary and neoplasia
Genetic background influences tumour phenotype in heterozygous Men1 knockout mice
K Lines
OC5.2
Oral Communications 5: Pituitary and neoplasia
The role of the microRNA miR-34a in the regulation of aryl hydrocarbon receptor interacting protein (AIP)
J Denes
OC5.3
Oral Communications 5: Pituitary and neoplasia
Whole-exome sequencing studies of non-functioning pituitary adenomas
Paul Newey
Dundee, United Kingdom
OC5.4
Oral Communications 5: Pituitary and neoplasia
Clinical, metabolic, biochemical and radiological characterisation of patients with thyrotropinomas reveals a highly variable phenotype
O Koulouri
OC5.5
Oral Communications 5: Pituitary and neoplasia
Densely and sparsely granulated somatotroph adenomas - clinical, genetic and histological differences
S Larkin
OC5.6
Oral Communications 5: Pituitary and neoplasia
Manipulating PBF/PTTG1IP phosphorylation status to improve radioiodine uptake in thyroid and other tumours
V Smith
OC5.7
Oral Communications 5: Pituitary and neoplasia
Uterine tumours with loss of progesterone receptor expression develop in mice deleted for a Cell Division Cycle 73 (CDC73) allele
G Walls
OC5.8
Oral Communications 5: Pituitary and neoplasia
Pituitary adenoma and phaeochromocytoma/paraganglioma - a novel syndrome with a heterogeneous genetic background
J Denes
16:30 - 17:30
Debate
This house believes that radio iodine should be the first-line treatment for all patients with Graves' disease
MAIN AUDITORIUM
Chairs: J Lazarus (Cardiff) & TBC
D1.1
Debate
FOR
J Franklyn
D1.2
Debate
AGAINST
A Weetman
17:45 - 18:30
Meet the Expert 5
Supported by Clinical Endocrinology and the British Thyroid Foundation
HALL D
Chair: Jackie Gilbert (London)
MTE5
Meet the Expert 5
Challenges in managing hyperthroidism in young people
T Cheetham
19:30 - 00:00
Conference dinner
ROYAL HALL
Wednesday 20 March
24 sessions
07:00 - 07:15
BREAKFAST
QUEEN'S SUITE FOYER
07:15 - 08:00
Meet the Expert 7
SUPPORTED BY CLINICAL ENDOCRINOLOGY
QUEEN'S SUITE A
Chair: P Bouloux (London)
MTE7
Meet the Expert 7
Hormone misuse in sport and leisure
R Holt
07:15 - 08:00
Meet the Expert 6
Supported by Clinical Endocrinology and the Association for Multiple Endocrine Neoplasia Disorders
QUEEN'S SUITE B
Chair: P Trainer (Manchester)
MTE 6
Meet the Expert 6
Malignant Phaeochromocytoma
A Grossman
07:45 - 08:00
BREAKFAST
MAIN AUDITORIUM FOYER
08:10 - 08:45
ANNUAL GENERAL MEETING
MAIN AUDITORIUM
09:00 - 11:00
Nurse Session 1: The Patient Pathway for Pituitary Care
KINDLY SPONSORED BY VIROPHARMA
QUEEN'S SUITE B
Chairs: P Pickett (Shrewsbury) & C Jagger (Huddersfield)
N1.1
Nurse Session 1: The Patient Pathway for Pituitary Care
Overview and workup
S Aylwin
N1.2
Nurse Session 1: The Patient Pathway for Pituitary Care
Peri-operative care-surgical aspects
N Gordon
N1.3
Nurse Session 1: The Patient Pathway for Pituitary Care
The Surgery
N Thomas
N1.4
Nurse Session 1: The Patient Pathway for Pituitary Care
Radiotherapy and post operative management
D Landau
N1.5
Nurse Session 1: The Patient Pathway for Pituitary Care
Post-operative and follow-up care
P Coskeran
09:00 - 11:00
Symposium 10: Lipodystrophy - The perils of being thin
MAIN AUDITORIUM
Chairs: S O'Rahilly (Cambridge) & G Tan (Nottingham)
S10.1
Symposium 10: Lipodystrophy - The perils of being thin
Familial partial lipodystrophy: an introduction
S Cinti
S10.2
Symposium 10: Lipodystrophy - The perils of being thin
Novel genetic causes of partial lipdystrophy
D Savage
S10.3
Symposium 10: Lipodystrophy - The perils of being thin
HIV and lipodystrophy
F Villarroya
Barcelona, Spain
S10.4
Symposium 10: Lipodystrophy - The perils of being thin
Approach to lipodystrophy management - a new national service
A Stears
09:00 - 11:00
Symposium 9: Novel aspects of GPCR signalling
Supported by the Journal of Endocrinology
QUEEN'S SUITE A
Chairs: A Hanyaloglu (London) & K Jonas (London)
S9.1
Symposium 9: Novel aspects of GPCR signalling
GPCR mutations and reproduction
U Kaiser
Boston, USA
S9.2
Symposium 9: Novel aspects of GPCR signalling
Novel aspects of TSH receptor signalling
M Gershengorn
Bethesda, USA
S9.3
Symposium 9: Novel aspects of GPCR signalling
In vivo dimerization of LH receptors
I Huhtaniemi
S9.4
Symposium 9: Novel aspects of GPCR signalling
Allosteric LH receptor regulation
C Koppen
Saarbrucken, Germany
10:00 - 11:00
Education Workshop 2: How to get your research published
Hear from the Editors of the Society’s official journals how to maximise your chances of publishing your work in top endocrine journals. Hints, tips and questions answered on what Editors look for when assessing a paper.
HALL D
EW2.1
Education Workshop 2: How to get your research published
Endocrine Connections
J Christiansen
Aarhus, Denmark
EW2.2
Education Workshop 2: How to get your research published
Endocrine-Related Cancer
F Weber
Essen, Germany
EW2.3
Education Workshop 2: How to get your research published
Journal of Endocrinology
A Clark
EW2.4
Education Workshop 2: How to get your research published
Journal of Molecular Endocrinology
A Clark
EW2.5
Education Workshop 2: How to get your research published
Clinical Endocrinology
J Bevan
EW2.6
Education Workshop 2: How to get your research published
Question & answer session
11:00 - 11:30
TEA & COFFEE
HALL H
11:30 - 12:00
SfE European Medal Lecture
MAIN AUDITORIUM
Chair: C McCabe (Birmingham)
PL3
SfE European Medal Lecture
cAMP in the pituitary: An old messenger for multiple signals
A Spada
Milan, Italy on behalf of the author group
12:00 - 12:30
SfE Translatlantic Medal Lecture
MAIN AUDITORIUM
Chair: A Grossman (Oxford)
PL4
SfE Translatlantic Medal Lecture
Environmental regulation of neuroendocrine systems through epigenetic mechanisms
M Meaney
Montreal, Canada
12:30 - 13:45
LUNCH
HALL H
12:30 - 13:30
Viropharma satellite symposium
Current management of adrenal insufficiency: challenges and innovations
QUEEN'S SUITE A (lunch available in QS foyer)
Chair: P Stewart (Birmingham)
Viropharma satellite symposium
Current challenges in the management of AI: why current therapy fails our patients
P Stewart
Birmingham, UK
Viropharma satellite symposium
Current challenges in the management of AI: goals of therapy
A Grossman
Viropharma satellite symposium
How a dual-release preparation can help overcome challenges
G Johannsson
Gothenburg, Sweden
Viropharma satellite symposium
Panel
13:45 - 15:45
Nurse Session 2: Late Effects
KINDLY SPONSORED BY VIROPHARMA
QUEEN'S SUITE B
Chairs: L Shepherd (Birmingham) & J Lynch (Leeds)
N2.1
Nurse Session 2: Late Effects
Pituitary late effects
Robert Murray
Leeds, UK
N2.2
Nurse Session 2: Late Effects
Thyroid late effects
G Brabant
N2.3
Nurse Session 2: Late Effects
Gonadal late effects
Maralyn Druce
London, UK
13:45 - 15:45
Symposium 12: Thymic function and autoimmune endocrine disease
Defects in central tolerance of T cells in the thymus predispose to autoimmunity
QUEEN'S SUITE A
Chairs: D Renshaw (London) & M Simmonds (Oxford)
S12.1
Symposium 12: Thymic function and autoimmune endocrine disease
The thymus medulla, Aire, and autoimmunity
G Anderson
S12.2
Symposium 12: Thymic function and autoimmune endocrine disease
Anti-cytokine autoantibodies in AIRE deficient humans and mice
P Peterson
S12.3
Symposium 12: Thymic function and autoimmune endocrine disease
Attacking the endocrine system: what is AIRE doing?
Y Takahama
Tokushima, Japan
S12.4
Symposium 12: Thymic function and autoimmune endocrine disease
Regulatory T cells, CTLA-4 and autoimmune disease
D Sansom
13:45 - 15:45
Symposium 11: Guts, brains and bariatric surgery
How bariatric surgery works
MAIN AUDITORIUM
Chairs: S O'Rahilly (Cambridge) & R Stimson (Edinburgh)
S11.1
Symposium 11: Guts, brains and bariatric surgery
How does bariatric surgery cure obesity?
C Roux
S11.2
Symposium 11: Guts, brains and bariatric surgery
Gut-brain communication - Ghrelin
S Dickson
Gothenburg, Sweden
S11.3
Symposium 11: Guts, brains and bariatric surgery
Targeting gut hormone release to treat obesity
F Gribble
S11.4
Symposium 11: Guts, brains and bariatric surgery
Gut hormones: a cure for obesity
Stephen Bloom
13:45 - 14:30
Meet The Expert 8
HALL D
Chair: J Davis (Manchester)
MTE8
Meet The Expert 8
Live Cell Imaging
R Duncan
15:00 - 15:45
Meet The Expert 9
HALL D
Chair: G Lavery (Birmingham)
MTE9
Meet The Expert 9
Biomedical mass spectrometry - moving forward
R Andrew
Edinburgh, UK
15:45 - 16:15
TEA & COFFEE
HALL H
16:15 - 16:45
Awards Ceremony
MAIN AUDITORIUM
16:45 - 17:15
BTA Pitt-Rivers Lecture
SUPPORTED BY CLINICAL ENDOCRINOLOGY TRUST
MAIN AUDITORIUM
Chair: G Williams (London)
PL5
BTA Pitt-Rivers Lecture
Regulation of Tissue-Specific Regulation of Thyroid Hormone Action
A Bianco
Miami, USA
16:45 -
EXHIBITION CLOSES
17:15 - 17:45
SfE Medal Lecture
MAIN AUDITORIUM
Chair: A Grossman (Oxford)
PL6
SfE Medal Lecture
Genes and Giants
Márta Korbonits
Thursday 21 March
14 sessions
07:15 - 07:30
BREAKFAST
QUEEN'S SUITE FOYER
07:30 - 08:15
Meet The Expert 3 (Repeated)
QUEEN'S SUITE A
07:30 - 08:15
Meet The Expert 5 (Repeated)
QUEEN'S SUITE B
08:30 - 09:00
Clincal Endocrinology Trust Lecture
SUPPORTED BY CLINICAL ENDOCRINOLOGY TRUST
MAIN AUDITORIUM
Chair: S Ball (Newcastle)
PL7
Clincal Endocrinology Trust Lecture
The dynamics of hypothalamic-pituitary-adrenal activity
S Lightman
09:00 - 09:30
Clinical Endocrinology Trust Visiting Professor Lecture
SUPPORTED BY CLINICAL ENDOCRINOLOGY TRUST
MAIN AUDITORIUM
Chair: J Connell (Dundee)
PL8
Clinical Endocrinology Trust Visiting Professor Lecture
Evaluation of the adrenal cortex: Future possibilities
L Nieman
Bethesda, USA
09:30 - 10:00
Clinical Guidelines
MAIN AUDITORIUM
Chairs: A Toogood (Birmingham) & B Walker (Edinburgh)
CG1.1
Clinical Guidelines
Consequences of cancer therapy
J Wass
CG1.2
Clinical Guidelines
Adults with CAH
W Arlt
10:00 - 10:30
TEA & COFFEE
MAIN AUDITORIUM & QUEEN'S SUITE FOYER
10:30 - 12:30
Clinical Management Workshop 4: Managing Hypoglycaemia
SUPPORTED BY CLINICAL ENDOCRINOLOGY
MAIN AUDITORIUM
Chairs: K Meeran (London) & B Challis (Cambridge)
CMW4.1
Clinical Management Workshop 4: Managing Hypoglycaemia
Hypoglycaemia in diabetes - effects on cerebral and autonomic function
S Amiel
CMW4.2
Clinical Management Workshop 4: Managing Hypoglycaemia
Insulinoma - new developments in localisation and therapy
J Service
Rochester, USA
CMW4.3
Clinical Management Workshop 4: Managing Hypoglycaemia
Hypoglycaemia in neonates and children
K Hussain
CMW4.4
Clinical Management Workshop 4: Managing Hypoglycaemia
Autoimmune hypoglycaemia - when and how to look for anti-insulin and anti-insulin receptor antibodies
Robert Semple
Edinburgh, UK
10:30 - 12:30
Clinical Management Workshop 3: PCOS - why, how and what
SUPPORTED BY CLINICAL ENDOCRINOLOGY
QUEEN'S SUITE A
Chairs: G Conway (London) & S Atkin (Hull)
CMW3.1
Clinical Management Workshop 3: PCOS - why, how and what
Consensus on women's health aspects of PCOS
A Balen
CMW3.2
Clinical Management Workshop 3: PCOS - why, how and what
Treatment of PCOS in Non-Obese Adolescents
L Ibanez
Barcelona, Spain
CMW3.3
Clinical Management Workshop 3: PCOS - why, how and what
Is there a place for Metformin in PCOS?
R Legro
Hershey, USA
CMW3.4
Clinical Management Workshop 3: PCOS - why, how and what
Diagnosis and Management of hirsuitism
H Escobar-Morreale
Madrid, Spain
10:30 - 13:00
Senior Endocrinologists' Session
HALL D
Chairs: B Cooke & P Belchetz
SE1.1
Senior Endocrinologists' Session
The UK is an underdeveloped country - The Iodine Scandal
J Lazarus
SE1.2
Senior Endocrinologists' Session
Robert Graves and his remarkable colleagues
J McKenna
Dublin, Ireland
SE1.3
Senior Endocrinologists' Session
Should the Aging Male Become a Father?
E Nieschlag
Muenster, Germany
SE1.4
Senior Endocrinologists' Session
Vitamin D action on the Renin/Angiotensin system in pancreas and liver
B Boucher
SE1.5
Senior Endocrinologists' Session
Type 1 and Type 2 Diabetes are the same disorder of insulin resistance, but with different genetic backgrounds
T Wilkin
SE1.6
Senior Endocrinologists' Session
Suspicious hypoglycaemia: was it insulin?
V Marks
12:30 - 13:15
Meet The Expert 1 (Repeated)
QUEEN'S SUITE A
12:30 - 13:15
Meet The Expert 2 (Repeated)
QUEEN'S SUITE B
13:30 - 14:15
Meet The Expert 6 (Repeated)
QUEEN'S SUITE A
13:30 - 14:15
Meet The Expert 7 (Repeated)
QUEEN'S SUITE B
S Amiel
Thu 21
10:30
CMW4.1
Clinical Management Workshop 4: Managing Hypoglycaemia
Hypoglycaemia in diabetes - effects on cerebral and autonomic function
S Amiel
G Anderson
Wed 20
13:45
S12.1
Symposium 12: Thymic function and autoimmune endocrine disease
The thymus medulla, Aire, and autoimmunity
G Anderson
R Andrew
Edinburgh, UK
Wed 20
MTE9
Meet The Expert 9
Biomedical mass spectrometry - moving forward
R Andrew
Edinburgh, UK
W Arlt
Thu 21
09:45
CG1.2
Clinical Guidelines
Adults with CAH
W Arlt
S Aylwin
Wed 20
09:00
N1.1
Nurse Session 1: The Patient Pathway for Pituitary Care
Overview and workup
S Aylwin
John Ayuk
Birmingham
Tue 19
08:35
CMW2.2
Clinical Management Workshop 2: How Do I Do It?
How do I investigate and manage hypomagnesaemia?
John Ayuk
Birmingham
A Balen
Thu 21
10:30
CMW3.1
Clinical Management Workshop 3: PCOS - why, how and what
Consensus on women's health aspects of PCOS
A Balen
I Banerjee
Tue 19
09:35
CMW2.5
Clinical Management Workshop 2: How Do I Do It?
How and when do I induce puberty in males?
I Banerjee
S Baron-Cohen
Mon 18
16:15
S5.1
Symposium 5: Sex in the brain
Foetal testosterone in mind
S Baron-Cohen
P Beck-Peccoz
Milan, Italy
Tue 19
15:00
S7.3
Symposium 7: Thyroid Hormone Receptors - mutations and implications
Human thyroid hormone receptor beta mutations - syndrome of resistance to thyroid hormone
P Beck-Peccoz
Milan, Italy
G Begum
Tue 19
14:45
OC4.3
Oral Communications 4: Obesity, metabolism and bone
Adult offspring of undernourished sheep exhibit epigenetic alterations in HPA axis glucocorticoid receptor
G Begum
L Bentley
Mon 18
17:30
OC2.6
Oral Communications 2: Steroids and thyroid
An N-ethyl-N-nitrosourea induced Corticotrophin releasing hormone (Crh) promoter mutation provides a mouse model of Cushing’s syndrome
L Bentley
J Bevan
Tue 19
09:15
CMW2.4
Clinical Management Workshop 2: How Do I Do It?
How do I manage the pregnant patient with a prolactinoma?
J Bevan
Tue 19
Ipsen satellite symposium
High-dose lanreotide Autogel for treatment-naive patients with acromegaly: the PRIMARYS trial
J Bevan
Wed 20
10:30
EW2.5
Education Workshop 2: How to get your research published
Clinical Endocrinology
J Bevan
A Bianco
Miami, USA
Wed 20
PL5
BTA Pitt-Rivers Lecture
Regulation of Tissue-Specific Regulation of Thyroid Hormone Action
A Bianco
Miami, USA
Stephen Bloom
Wed 20
15:15
S11.4
Symposium 11: Guts, brains and bariatric surgery
Gut hormones: a cure for obesity
Stephen Bloom
B Boucher
Thu 21
11:45
SE1.4
Senior Endocrinologists' Session
Vitamin D action on the Renin/Angiotensin system in pancreas and liver
B Boucher
G Brabant
Wed 20
14:25
N2.2
Nurse Session 2: Late Effects
Thyroid late effects
G Brabant
M Brandi
Florence, Italy
Mon 18
16:15
CMW1.1
Clinical Management Workshop 1: Management controversies in parathyroid disease
Hyperparathyroidism in MEN1
M Brandi
Florence, Italy
T Brue
Marseille, France
Tue 19
18:00
S8.4
Symposium 8: Non functioning pituitary tumours
Aggressive pituitary tumours and temozolomide treatment
T Brue
Marseille, France
J Cegia
Tue 19
15:00
OC4.5
Oral Communications 4: Obesity, metabolism and bone
Energy intake following infusion of glucagon and GLP-1: a double-blind crossover study
J Cegia
T Cheetham
Tue 19
17:45
MTE5
Meet the Expert 5
Challenges in managing hyperthroidism in young people
T Cheetham
D Chen
Mon 18
18:00
OC2.8
Oral Communications 2: Steroids and thyroid
When math meets biology: systems approach to drug resistance analysis
D Chen
S Chen
Tue 19
08:30
OC3.2
Oral Communications 3: Reproduction, growth and development
Heterodimerisation of gonadotrophin hormone receptors modifies the LH-induced calcium signalling profile
S Chen
S-Y Cheng
Bethesda, USA
Tue 19
15:30
S7.4
Symposium 7: Thyroid Hormone Receptors - mutations and implications
Nuclear coregulators confer the actions of mutant thyroid hormone receptor alpha and beta
S-Y Cheng
Bethesda, USA
J Christiansen
Aarhus, Denmark
Wed 20
10:00
EW2.1
Education Workshop 2: How to get your research published
Endocrine Connections
J Christiansen
Aarhus, Denmark
S Cinti
Wed 20
09:00
S10.1
Symposium 10: Lipodystrophy - The perils of being thin
Familial partial lipodystrophy: an introduction
S Cinti
A Clark
Wed 20
10:20
EW2.3
Education Workshop 2: How to get your research published
Journal of Endocrinology
A Clark
Wed 20
10:25
EW2.4
Education Workshop 2: How to get your research published
Journal of Molecular Endocrinology
A Clark
A Comninos
Mon 18
15:30
OC1.8
Oral Communications 1: Young Endocrinologists's Prize Session
Kisspeptin advances ovulation in healthy women
A Comninos
J Connell
Tue 19
MTE3
Meet the Expert 3
Investigation of patients with suspected mineralocorticoid hypertension
J Connell
G Conway
Tue 19
MTE1
Meet the Expert 1
Turner Syndrome / pregnancy / cardiac risk
G Conway
B Conway-Campbell
Tue 19
08:45
S6.2
Symposium 6: Making the glucocorticoid clock run smoothly
Molecular dynamics of ultradian glucocorticoid receptor action
B Conway-Campbell
P Coskeran
Wed 20
10:45
N1.5
Nurse Session 1: The Patient Pathway for Pituitary Care
Post-operative and follow-up care
P Coskeran
J Denes
Tue 19
16:45
OC5.2
Oral Communications 5: Pituitary and neoplasia
The role of the microRNA miR-34a in the regulation of aryl hydrocarbon receptor interacting protein (AIP)
J Denes
Tue 19
18:15
OC5.8
Oral Communications 5: Pituitary and neoplasia
Pituitary adenoma and phaeochromocytoma/paraganglioma - a novel syndrome with a heterogeneous genetic background
J Denes
T Dickmeis
Karlsruhe, Germany
Tue 19
08:15
S6.1
Symposium 6: Making the glucocorticoid clock run smoothly
Monitoring glucocorticoid signalling and circadian clock function with transgenic zebrafish reporter lines
T Dickmeis
Karlsruhe, Germany
S Dickson
Gothenburg, Sweden
Wed 20
14:15
S11.2
Symposium 11: Guts, brains and bariatric surgery
Gut-brain communication - Ghrelin
S Dickson
Gothenburg, Sweden
M Donaldson
Tue 19
09:55
CMW2.6
Clinical Management Workshop 2: How Do I Do It?
How do I - and how should I - induce puberty in females?
M Donaldson
A Drakesmith
Mon 18
11:30
S1.2
Symposium 1: Irn Bru, to drink or not to drink: endocrinology and iron
The iron regulatory hormone hepcidin
A Drakesmith
S Driesche
Tue 19
09:15
OC3.5
Oral Communications 3: Reproduction, growth and development
Effects of in utero exposure to acetaminophen (paracetamol) on steroidogenesis by the rat and human fetal testis
S Driesche
Maralyn Druce
London, UK
Wed 20
15:05
N2.3
Nurse Session 2: Late Effects
Gonadal late effects
Maralyn Druce
London, UK
C Dulac
Cambridge, USA
Mon 18
17:15
S5.3
Symposium 5: Sex in the brain
Neuronal circuits underlying sex specific social behaviour
C Dulac
Cambridge, USA
R Duncan
Wed 20
MTE8
Meet The Expert 8
Live Cell Imaging
R Duncan
R Eastell
Mon 18
13:45
S4.1
Symposium 4: New Bone Biology - Is there life after RANK ligand?
New bone biology and Cathepsin K inhibitors
R Eastell
P Esbrit
Madrid, Spain
Mon 18
14:45
S4.3
Symposium 4: New Bone Biology - Is there life after RANK ligand?
Parathyroid hormone related peptide as a potential treatment for osteoporosis
P Esbrit
Madrid, Spain
H Escobar-Morreale
Madrid, Spain
Thu 21
12:00
CMW3.4
Clinical Management Workshop 3: PCOS - why, how and what
Diagnosis and Management of hirsuitism
H Escobar-Morreale
Madrid, Spain
R Evans
La Jolla, USA
Mon 18
11:00
S1.1
Symposium 1: Irn Bru, to drink or not to drink: endocrinology and iron
Iron homeostasis: who are the major players?
R Evans
La Jolla, USA
Tue 19
PL1
SfE Dale Medal Lecture
Nuclear receptors and AMPK: can exercise mimetics cure diabetes?
R Evans
La Jolla, USA
P Foster
Tue 19
14:45
YE1.4
YE Symposium: Maintaining your endocrine career despite what life throws at you
Non-traditional career paths towards an acedemic career
P Foster
R Fowkes
Mon 18
16:15
EW1.1
Education Workshop 1: Teaching and Learning in Endocrinology
Undergraduate research participation: going beyond 'students as producers'
R Fowkes
J Franklyn
Tue 19
16:30
D1.1
Debate
FOR
J Franklyn
W Fraser
Mon 18
16:45
CMW1.2
Clinical Management Workshop 1: Management controversies in parathyroid disease
Parathyroid hormone, vitamin D and chronic kidney disease
W Fraser
T Freeman
Mon 18
14:45
APW1.3
Applied Physiology Workshop
Analysis and visualisation of biological networks
T Freeman
C Gaston-Massuet
Mon 18
18:00
YEP1.2
Young Endocrinologists Prize Lectures
Pituitary development: the answer, is blowing in the Wnt
C Gaston-Massuet
L Gathercole
Mon 18
14:30
OC1.4
Oral Communications 1: Young Endocrinologists's Prize Session
A Serum MicroRNA Profile Potentially Associated with Glucocorticoid Mediated Insulin Resistance
L Gathercole
M Gershengorn
Bethesda, USA
Wed 20
09:30
S9.2
Symposium 9: Novel aspects of GPCR signalling
Novel aspects of TSH receptor signalling
M Gershengorn
Bethesda, USA
A Gogakos
Mon 18
17:00
OC2.4
Oral Communications 2: Steroids and thyroid
THRA or DIO2 mutations are not a common cause of high bone mass in humans
A Gogakos
N Gordon
Wed 20
09:30
N1.2
Nurse Session 1: The Patient Pathway for Pituitary Care
Peri-operative care-surgical aspects
N Gordon
F Gribble
Wed 20
14:45
S11.3
Symposium 11: Guts, brains and bariatric surgery
Targeting gut hormone release to treat obesity
F Gribble
A Grossman
Tue 19
Ipsen satellite symposium
Stabilising tumour growth in patients with NETs
A Grossman
Wed 20
MTE 6
Meet the Expert 6
Malignant Phaeochromocytoma
A Grossman
Wed 20
Viropharma satellite symposium
Current challenges in the management of AI: goals of therapy
A Grossman
M Gurnell
Tue 19
Ipsen satellite symposium
Tumour response to presurgical lanreotide Autogel therapy in the ACROPAT trial
M Gurnell
L Hand
Tue 19
10:00
OC3.8
Oral Communications 3: Reproduction, growth and development
Adiponectin induces GSK3 kinase-mediated cross-tolerance to endotoxin in macrophages
L Hand
N Hanley
Tue 19
16:30
MTE4
Meet The Expert 4
Induced plurripotent stem cells as an endocrine tool
N Hanley
P Hannaert
Poitiers, France
Mon 18
15:15
APW1.4
Applied Physiology Workshop
Modelling the circulating renin-angiotensin system and its efefcts on blood pressure
P Hannaert
Poitiers, France
R Hardy
Tue 19
09:45
OC3.7
Oral Communications 3: Reproduction, growth and development
Disruption of Mesenchymal Glucocorticoid Signaling Attenuates Embryonic Lung Development and Results in Post Natal Lethality in Mice
R Hardy
Z Hassan-Smith
Mon 18
14:15
OC1.3
Oral Communications 1: Young Endocrinologists's Prize Session
11β-HSD1KO mice are protected from glucocorticoid dependent age-associated muscle atrophy
Z Hassan-Smith
R Holt
Wed 20
07:15
MTE7
Meet the Expert 7
Hormone misuse in sport and leisure
R Holt
D Hosking
Mon 18
17:45
CMW1.4
Clinical Management Workshop 1: Management controversies in parathyroid disease
Medical management of parathyroid disease
D Hosking
S Howles
Mon 18
15:15
OC1.7
Oral Communications 1: Young Endocrinologists's Prize Session
Autosomal dominant hypocalcemia type 2 is caused by germline GNA11 gain-of-function mutations
S Howles
T Howlett
Tue 19
14:30
YE1.3
YE Symposium: Maintaining your endocrine career despite what life throws at you
Getting useful research results from routine NHS activity
T Howlett
I Huhtaniemi
Wed 20
10:00
S9.3
Symposium 9: Novel aspects of GPCR signalling
In vivo dimerization of LH receptors
I Huhtaniemi
K Hussain
Thu 21
11:30
CMW4.3
Clinical Management Workshop 4: Managing Hypoglycaemia
Hypoglycaemia in neonates and children
K Hussain
L Ibanez
Barcelona, Spain
Thu 21
11:00
CMW3.2
Clinical Management Workshop 3: PCOS - why, how and what
Treatment of PCOS in Non-Obese Adolescents
L Ibanez
Barcelona, Spain
S Jamal
Toronto, Canada
Mon 18
15:15
S4.4
Symposium 4: New Bone Biology - Is there life after RANK ligand?
Organic nitrates for the treatment of postmenopausal osteoporosis
S Jamal
Toronto, Canada
N James
Tue 19
08:15
CMW2.1
Clinical Management Workshop 2: How Do I Do It?
How do I manage testosterone replacement after prostate cancer therapy?
N James
F Jean-Alphonse
Tue 19
08:15
OC3.1
Oral Communications 3: Reproduction, growth and development
Identification of very early sorting endosomes that spatially program gonadotrophin hormone receptor signalling
F Jean-Alphonse
G Johannsson
Gothenburg, Sweden
Wed 20
Viropharma satellite symposium
How a dual-release preparation can help overcome challenges
G Johannsson
Gothenburg, Sweden
Kim Jonas
London, UK
Tue 19
08:45
OC3.3
Oral Communications 3: Reproduction, growth and development
Regulation of G protein-coupling specificity via cis and trans activation of the luteinising hormone/chorionic gonadotrophin receptor (LHCGR)
Kim Jonas
London, UK
U Kaiser
Boston, USA
Wed 20
09:00
S9.1
Symposium 9: Novel aspects of GPCR signalling
GPCR mutations and reproduction
U Kaiser
Boston, USA
Niki Karavitaki
Birmingham, UK
Tue 19
16:30
S8.1
Symposium 8: Non functioning pituitary tumours
Epidemiology and natural history of pituitary tumours
Niki Karavitaki
Birmingham, UK
E Keverne
Mon 18
16:45
S5.2
Symposium 5: Sex in the brain
Importance of genomic imprinting in the evolution and development of the maternal brain
E Keverne
C Koppen
Saarbrucken, Germany
Wed 20
10:30
S9.4
Symposium 9: Novel aspects of GPCR signalling
Allosteric LH receptor regulation
C Koppen
Saarbrucken, Germany
Márta Korbonits
Wed 20
PL6
SfE Medal Lecture
Genes and Giants
Márta Korbonits
O Koulouri
Tue 19
17:15
OC5.4
Oral Communications 5: Pituitary and neoplasia
Clinical, metabolic, biochemical and radiological characterisation of patients with thyrotropinomas reveals a highly variable phenotype
O Koulouri
F Labrie
Quebec, Canada
Tue 19
PL2
SfE Hoffenberg International Medal Lecture
Multiple applications of intracrinology in clinical medicine
F Labrie
Quebec, Canada
D Landau
Wed 20
10:15
N1.4
Nurse Session 1: The Patient Pathway for Pituitary Care
Radiotherapy and post operative management
D Landau
S Larkin
Tue 19
17:30
OC5.5
Oral Communications 5: Pituitary and neoplasia
Densely and sparsely granulated somatotroph adenomas - clinical, genetic and histological differences
S Larkin
G Lavery
Tue 19
14:00
YE1.1
YE Symposium: Maintaining your endocrine career despite what life throws at you
Maintaining an active basic research career whilst juggling an academic and personal life
G Lavery
J Lazarus
Thu 21
10:30
SE1.1
Senior Endocrinologists' Session
The UK is an underdeveloped country - The Iodine Scandal
J Lazarus
G Leese
Mon 18
17:15
CMW1.3
Clinical Management Workshop 1: Management controversies in parathyroid disease
'Mild hyperparathyroidism' - what determines clinical outcome?
G Leese
R Legro
Hershey, USA
Thu 21
11:30
CMW3.3
Clinical Management Workshop 3: PCOS - why, how and what
Is there a place for Metformin in PCOS?
R Legro
Hershey, USA
G Leng
Mon 18
13:45
APW1.1
Applied Physiology Workshop
Modelling neuroendocrine systems
G Leng
M Levy
Mon 18
17:15
EW1.3
Education Workshop 1: Teaching and Learning in Endocrinology
Recommended standards for undergraduate medical education
M Levy
S Lightman
Thu 21
PL7
Clincal Endocrinology Trust Lecture
The dynamics of hypothalamic-pituitary-adrenal activity
S Lightman
K Lines
Tue 19
16:30
OC5.1
Oral Communications 5: Pituitary and neoplasia
Genetic background influences tumour phenotype in heterozygous Men1 knockout mice
K Lines
D Livingstone
Tue 19
15:15
OC4.6
Oral Communications 4: Obesity, metabolism and bone
Transgenic disruption of 5alpha-reductase1 increases susceptibility to liver fibrosis
D Livingstone
L Lumey
Columbia, USA
Mon 18
12:00
S3.3
Symposium 3: Nurture not nature: epigenetics and disease susceptibility
Epigenetic differences associated with prenatal exposure to famine in humans
L Lumey
Columbia, USA
A Madathil
Mon 18
16:30
OC2.2
Oral Communications 2: Steroids and thyroid
Abnormal cardiac bio-energetics in subclinical hypothyroidism; cardiac magnetic resonance spectroscopic study
A Madathil
V Marks
Thu 21
12:35
SE1.6
Senior Endocrinologists' Session
Suspicious hypoglycaemia: was it insulin?
V Marks
J McKenna
Dublin, Ireland
Thu 21
10:55
SE1.2
Senior Endocrinologists' Session
Robert Graves and his remarkable colleagues
J McKenna
Dublin, Ireland
M Meaney
Montreal, Canada
Wed 20
PL4
SfE Translatlantic Medal Lecture
Environmental regulation of neuroendocrine systems through epigenetic mechanisms
M Meaney
Montreal, Canada
S Morgan
Tue 19
14:15
OC4.2
Oral Communications 4: Obesity, metabolism and bone
11β-HSD1 Knockout Mice are Protected from the Adverse Metabolic Effects of Exogenous Glucocorticoid Excess
S Morgan
Robert Murray
Leeds, UK
Wed 20
13:45
N2.1
Nurse Session 2: Late Effects
Pituitary late effects
Robert Murray
Leeds, UK
D Nanus
Mon 18
13:45
OC1.1
Oral Communications 1: Young Endocrinologists's Prize Session
TNFα directly regulates in vivo corticosteroid metabolism in inflammatory arthritis
D Nanus
S Nef
Geneva, Switzerland
Mon 18
11:30
S2.2
Symposium 2: Hormones Maketh Man
The role of the Sertoli cell in driving 'maleness'
S Nef
Geneva, Switzerland
A Nesbit
Tue 19
15:30
OC4.7
Oral Communications 4: Obesity, metabolism and bone
Familial Hypocalciuric Hypercalcaemia Type 3 (FHH3) is Caused by Mutations in Adaptor Protein 2 Sigma 1 (AP2S1)
A Nesbit
Paul Newey
Dundee, United Kingdom
Tue 19
14:15
YE1.2
YE Symposium: Maintaining your endocrine career despite what life throws at you
Juggling a clinical workload: and academic research
Paul Newey
Dundee, United Kingdom
Tue 19
17:00
OC5.3
Oral Communications 5: Pituitary and neoplasia
Whole-exome sequencing studies of non-functioning pituitary adenomas
Paul Newey
Dundee, United Kingdom
L Nieman
Bethesda, USA
Thu 21
PL8
Clinical Endocrinology Trust Visiting Professor Lecture
Evaluation of the adrenal cortex: Future possibilities
L Nieman
Bethesda, USA
E Nieschlag
Muenster, Germany
Thu 21
11:20
SE1.3
Senior Endocrinologists' Session
Should the Aging Male Become a Father?
E Nieschlag
Muenster, Germany
G Papacleovaulou
Tue 19
14:45
OC4.4
Oral Communications 4: Obesity, metabolism and bone
Cholestatic pregnancy programmes metabolic disease in the offspring
G Papacleovaulou
S Papapoulos
Leiden, The Netherlands
Mon 18
14:15
S4.2
Symposium 4: New Bone Biology - Is there life after RANK ligand?
Inhibition of sclerostin in the treatment of osteoporosis
S Papapoulos
Leiden, The Netherlands
S Pearce
Newcastle, UK
Tue 19
09:45
S6.4
Symposium 6: Making the glucocorticoid clock run smoothly
Retraining the HPA axis: how to cure adrenal insufficiency
S Pearce
Newcastle, UK
K Perry
Tue 19
15:00
YE1.5
YE Symposium: Maintaining your endocrine career despite what life throws at you
Re-establishing your research profile after a career break (academic perspective)
K Perry
P Peterson
Wed 20
14:15
S12.2
Symposium 12: Thymic function and autoimmune endocrine disease
Anti-cytokine autoantibodies in AIRE deficient humans and mice
P Peterson
D Pfaff
New York, USA
Mon 18
17:45
S5.4
Symposium 5: Sex in the brain
Hormone-dependent chromatin modifications regulating sexually differentiated animal behaviour
D Pfaff
New York, USA
P Prasad
Mon 18
17:15
OC2.5
Oral Communications 2: Steroids and thyroid
A mutation in thioredoxin reductase 2 (TXNRD2) is associated with a predominantly adrenal phenotype in humans
P Prasad
V Rakyan
Mon 18
11:00
S3.1
Symposium 3: Nurture not nature: epigenetics and disease susceptibility
Epigenome-wide association studies for common human diseases
V Rakyan
R Rey
Buenos Aires, Argentina
Mon 18
11:00
S2.1
Symposium 2: Hormones Maketh Man
Anti-müllerian hormone - a Sertoli cell hormone that can be used as a predictor of male hypogonadism
R Rey
Buenos Aires, Argentina
R Richardson
Tue 19
14:00
OC4.1
Oral Communications 4: Obesity, metabolism and bone
Glucocorticoid receptor deficiency in cardiomyocytes causes pathological cardiac remodelling in mice.
R Richardson
R Robertson
Tue 19
09:30
OC3.6
Oral Communications 3: Reproduction, growth and development
Follistatin-Like 3 (FSTL3), a transforming growth factor β (TGFβ) ligand inhibitor, is essential for placental development in mice.
R Robertson
M Rodie
Tue 19
09:00
OC3.4
Oral Communications 3: Reproduction, growth and development
Characterising changes in the in vivo male rodent brain using Magnetic Resonance Spectroscopy
M Rodie
M Rodriguez-Fernandez
Santa Barbara, USA
Mon 18
14:15
APW1.2
Applied Physiology Workshop
Distinguishing normal, depressive and PTSD cortisol dynamics in humans through mathematical modelling
M Rodriguez-Fernandez
Santa Barbara, USA
R Ross
Tue 19
09:15
S6.3
Symposium 6: Making the glucocorticoid clock run smoothly
Diurnal cortisol delivery: a novel tool for adrenal insufficiency
R Ross
C Roux
Wed 20
13:45
S11.1
Symposium 11: Guts, brains and bariatric surgery
How does bariatric surgery cure obesity?
C Roux
G Ryan
Mon 18
16:45
OC2.3
Oral Communications 2: Steroids and thyroid
A bi-transgenic murine model of PTTG and PBF overexpression in the thyroid gland
G Ryan
D Sansom
Wed 20
15:15
S12.4
Symposium 12: Thymic function and autoimmune endocrine disease
Regulatory T cells, CTLA-4 and autoimmune disease
D Sansom
P Saunders
Tue 19
15:15
YE1.6
YE Symposium: Maintaining your endocrine career despite what life throws at you
Putting your best foot forward - what the funders' are looking for
P Saunders
D Savage
Wed 20
09:30
S10.2
Symposium 10: Lipodystrophy - The perils of being thin
Novel genetic causes of partial lipdystrophy
D Savage
N Schoenmakers
Mon 18
16:15
OC2.1
Oral Communications 2: Steroids and thyroid
Loss-of-Function Mutations in IGSF1 Cause a Novel, X-Linked Syndrome of Central Hypothyroidism and Testicular Enlargement
N Schoenmakers
L Seal
Tue 19
08:55
CMW2.3
Clinical Management Workshop 2: How Do I Do It?
How do I monitor and follow up transgender patients using hormonal therapies?
L Seal
P Selby
Mon 18
17:45
EW1.4
Education Workshop 1: Teaching and Learning in Endocrinology
Postgraduate training in endocrinolgoy and diabetes - developing the curriculum and assessments
P Selby
Robert Semple
Edinburgh, UK
Thu 21
12:00
CMW4.4
Clinical Management Workshop 4: Managing Hypoglycaemia
Autoimmune hypoglycaemia - when and how to look for anti-insulin and anti-insulin receptor antibodies
Robert Semple
Edinburgh, UK
J Service
Rochester, USA
Thu 21
11:00
CMW4.2
Clinical Management Workshop 4: Managing Hypoglycaemia
Insulinoma - new developments in localisation and therapy
J Service
Rochester, USA
A Sinha
Mon 18
15:00
OC1.6
Oral Communications 1: Young Endocrinologists's Prize Session
Improving the Vitamin D status of Vitamin D deficient adults is associated with improved mitochondrial oxidative function in skeletal muscle
A Sinha
L Smith
Mon 18
12:00
S2.3
Symposium 2: Hormones Maketh Man
Androgens and male fertility - a long way from the black box theory
L Smith
V Smith
Tue 19
17:45
OC5.6
Oral Communications 5: Pituitary and neoplasia
Manipulating PBF/PTTG1IP phosphorylation status to improve radioiodine uptake in thyroid and other tumours
V Smith
A Spada
Milan, Italy on behalf of the author group
Wed 20
PL3
SfE European Medal Lecture
cAMP in the pituitary: An old messenger for multiple signals
A Spada
Milan, Italy on behalf of the author group
A Stears
Wed 20
10:30
S10.4
Symposium 10: Lipodystrophy - The perils of being thin
Approach to lipodystrophy management - a new national service
A Stears
P Stewart
Birmingham, UK
Wed 20
Viropharma satellite symposium
Current challenges in the management of AI: why current therapy fails our patients
P Stewart
Birmingham, UK
Y Takahama
Tokushima, Japan
Wed 20
14:45
S12.3
Symposium 12: Thymic function and autoimmune endocrine disease
Attacking the endocrine system: what is AIRE doing?
Y Takahama
Tokushima, Japan
G Tan
Tue 19
MTE2
Meet the Expert 2
Diabetes metellitus, endocrinology and the impact of GP commissioning
G Tan
N Thomas
Wed 20
09:45
N1.3
Nurse Session 1: The Patient Pathway for Pituitary Care
The Surgery
N Thomas
A Tiganescu
Mon 18
17:45
OC2.7
Oral Communications 2: Steroids and thyroid
11β-hydroxysteroid dehydrogenase type 1: A role in skin wound healing
A Tiganescu
R Upreti
Mon 18
14:45
OC1.5
Oral Communications 1: Young Endocrinologists's Prize Session
Inhibition of 5α-reductase type 1 with dutasteride impairs insulin sensitivity
R Upreti
F Villarroya
Barcelona, Spain
Wed 20
10:00
S10.3
Symposium 10: Lipodystrophy - The perils of being thin
HIV and lipodystrophy
F Villarroya
Barcelona, Spain
G Walls
Mon 18
18:00
YEP1.1
Young Endocrinologists Prize Lectures
Clinical and pre-clinical studies of neuroendocrine tumours (NETs) in Multiple Endocrine Neoplasia type 1 (MEN1), and evaluation of MEN1 gene replacement therapy for MEN1-associated NETs.
G Walls
Tue 19
18:00
OC5.7
Oral Communications 5: Pituitary and neoplasia
Uterine tumours with loss of progesterone receptor expression develop in mice deleted for a Cell Division Cycle 73 (CDC73) allele
G Walls
J Wass
Thu 21
09:30
CG1.1
Clinical Guidelines
Consequences of cancer therapy
J Wass
F Weber
Essen, Germany
Wed 20
10:10
EW2.2
Education Workshop 2: How to get your research published
Endocrine-Related Cancer
F Weber
Essen, Germany
A Weetman
Tue 19
17:00
D1.2
Debate
AGAINST
A Weetman
Anne White
Manchester, UK
Mon 18
11:30
S3.2
Symposium 3: Nurture not nature: epigenetics and disease susceptibility
Nutritional programming of epigenetics in metabolic syndrome
Anne White
Manchester, UK
M Wierman
Denver, USA
Tue 19
17:00
S8.2
Symposium 8: Non functioning pituitary tumours
Pathological mechanisms underlying non-functioning pituitary tumours
M Wierman
Denver, USA
T Wilkin
Thu 21
12:10
SE1.5
Senior Endocrinologists' Session
Type 1 and Type 2 Diabetes are the same disorder of insulin resistance, but with different genetic backgrounds
T Wilkin
G Williams
Tue 19
14:00
S7.1
Symposium 7: Thyroid Hormone Receptors - mutations and implications
Physiologically distinct roles for thyroid hormone receptor isoforms
G Williams
D Wood
Mon 18
16:45
EW1.2
Education Workshop 1: Teaching and Learning in Endocrinology
Clinical skills delivery
D Wood
M Zatelli
Ferrara, Italy
Tue 19
17:30
S8.3
Symposium 8: Non functioning pituitary tumours
Pathological markers of aggressive pituitary tumour behaviour - use of MGMT?
M Zatelli
Ferrara, Italy
Z Zhang
Mon 18
14:00
OC1.2
Oral Communications 1: Young Endocrinologists's Prize Session
Macrophage-specific 11β-hydroxysteroid dehydrogenase type 1 deficiency promotes angiogenesis but impairs resolution of K/BxN serum induced arthritis
Z Zhang
H Zoller
Innsbruck, Austria
Mon 18
12:00
S1.3
Symposium 1: Irn Bru, to drink or not to drink: endocrinology and iron
'The Celtic disease' - haemochromatosis: a disease of iron overload
H Zoller
Innsbruck, Austria
Categories
Posters
Obesity, diabetes, metabolism and cardiovascular
P203
Evaluation of efficacy of transdermal delivery of chloroquine on Plasmodium berghei-infected male Sprague-Dawley rats and effects on blood glucose and renal electrolyte handling
Cephas T Murabayane
P206
ILEAL INTERPOSITION WITH DIVERTED SLEEVE GASTRECTOMY FOR TREATMENT OF TYPE 2 DIABETES
SUNIL KUMAR KOTA
P198
INFLAMMATORY MARKERS IN DIABETIC FOOT AND IMPACT OF VITAMIN D DEFICIENCY
SUNIL KUMAR KOTA
P207
Polycystic ovary syndrome has no independent effect on vascular, inflammatory or thrombotic markers when matched for obesity.
Hassan Kahal
P227
Short term calorie restriction : Effects on endocrine markers of nutritional status.
Swati Jain
P243
Re-occurrence of pancreatic insulinoma: an usual cause of hypoglycaemia
Charles Anwuzia-Iwegbu
P199
The Possible Involvement of the Receptor for Advanced Glycation End Products (RAGE) in Vascular Senescence in Diabetes
Nalinie Joharatnam
P236
Improvement in Testosterone post Bariatric surgery
Vani Shankaran
P228
The development of a structured education programme to improve cardiovascular risk in women with Polycystic Ovary Syndrome (SUCCESS Study)
Hamidreza Mani
P200
Effects of Syzygium aromaticum-derived oleanolic acid administration on postprandial glucose concentration and key intestinal carbohydrate hydrolyzing enzymes of streptozotocin-induced diabetic rats
Cephas T Musabayane
P241
Unusual case of Hypoglycaemia in diabetic patient
Aye Nyunt
P229
Hypogonadism in males with Type 2 Diabetes Mellitus
Adewole Adesanya
P183
The effects of Syzygium aromaticum-derived oleanolic acid on reactive oxygen species in the heart, liver and kidney of STZ-induced diabetic rats
Cephas T Musabayane
P208
Leptin in serum and vitreous humor, and retinal ob mRNA, in human diabetes.
Syed A Imran
P205
Irisin as a central regulator in energy homeostasis?
Milan K Piya
P230
Obesity-related hypogonadotrophic hypogonadism: recovery of normal pituitary-gonadal axis function following bariatric surgery
Anjali Santhakumar
P212
The Public distress domain of Quality of Life correlates directly and independently with BMI in pre-operative morbidly obese patients awaiting metabolic surgery
SYED ABDUS SABOOR AFTAB
P239
Preoperative characteristics of morbidly obese patients who achieved at least fifty percent excess weight loss post-metabolic Surgery
SYED ABDUS SABOOR AFTAB
P202
Vitamin D and insulin resistance: No association in healthy overweight people at high risk of cardiovascular disease.
Ian Wallace
P218
Weight loss after bariatric surgery in women of childbearing age
Aderinsola Alatishe
P213
Pregestational Body Mass Index Predicts Neonatal Hypoglycemia in Women with Gestational Diabetes
Ayesha Ahmad
P231
Risk Assessment of Adult Residents in Ile-Ife, South-Western Nigeria for Type 2 Diabetes Mellitus
Gbadebo Ajani
P184
Effects of Vitamin D supplementation on blood pressure, glucocorticoids and cardiovascular risk markers in healthy subjects
EMAD AL-DUJAILI
P219
Eating more quickly heightens overall systemic exposure to glucose and NEFA in the post-prandial phase, irrespective of energy expenditure in obese women
Thomas M Barber
P214
Effectiveness of bariatric surgery in women with and without polycystic ovarian syndrome
Angelos Kyriacou
P240
Glycaemic variability- does it make a difference in prediabetes?
Thomas Paul
P188
Human Abdominal Subcutaneous adipocytes as an active source of LpPLA2, influenced by fat depot and metabolic state, with LpPLA2 converting LDL into more potent atherogenic Ox-LDL, in vitro
Warunee Kumsaiyai
P232
Adrenal insufficiency post bariatric surgery
VANI SHANKARAN
P189
The role of glucocorticoid metabolism in bile acid homeostasis
Monica Naomi opiyo
P185
Knockdown of brain 11β-HSD1 does not lower body weight or improve insulin sensitivity
Erika Harno
P225
Non-Alcoholic Fatty Liver Disease in Patients Attending the National Severe Insulin Resistance Service.
Sarah M Leiter
P215
Octreotide therapy of chronic urticaria and angioedema after gastric bypass procedure
Jeanny Varghese
P220
Hepatic 11 ß-Hydroxysteroid Dehydrogenase Type 1 (11 ß-HSD1) is elevated following weight loss secondary to bariatric surgery.
Conor Woods
P237
Prevalence and Associated Risks for Metabolic Syndrome in Nigerians with Type 2 Diabetes Mellitus
David Soyoye
P209
The endocrine and metabolic characteristics of a large Bardet-Biedl syndrome clinic population
Safa Mujahid
P233
Pregnancy Outcome in a patient with Lipodystrophy and Type 2 Diabetes
Tolulope Shonibare
P180
A component of transcriptional PRC2 complex, enhancer of zest homology (EZH2), modulates endothelial cell responses to hypoxia and post-ischemic angiogenesis in a mouse model of limb ischemia
Tijana Mitic
P177
Association of calcium-sensing receptor polymorphisms with vascular calcification and glucose homeostasis in renal transplant recipients
Valerie N. Babinsky
P221
Brown adipose tissue identification in an adult human using IDEAL MRI
Narendra Reddy
P242
withdrawing insulin in a young person
mithun bhartia
P211