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Monday 24 March 20 sessions
    09:00 -  
    Registration
    11:00 - 12:30 
    Symposium 1: GnRH biology - from pulses to longevity
    Supported by Journal of Molecular Endocrinology
    1B
    Chairs: H Christian (Oxford) & R Perrett (Bristol)
    From novel insights into GnRH timing and central control of reproduction to new discoveries in hypothalamic inflammatory change and ageing
    11:30
    S1.2
    Biological insights from genetically tagged gonadotropes
    U Boehm
    12:00
    S1.3
    GnRH and inflammatory signalling in the ageing hypothalamus
    D Cai (Bronx, USA)
    11:00 - 12:30 
    Symposium 2: The upside of glucocorticoids in metabolism
    Supported by Journal of Endocrinology
    1C
    Chairs: R Stimson (Edinburgh) & S Morgan (Birmingham)
    Amending our thinking of the way GCs work
    11:00
    S2.1
    Insulin sensitisation of adipose tissue by glucocorticoids
    J Tomlinson
    11:30
    S2.2
    Maintaining the anti-inflammatory action of glucocorticoid without the metabolic side effects
    C Cummins (Toronto, Canada)
    12:00
    S2.3
    Glucocorticoids and protection from pancreatic beta cell failure
    N Morton
    11:00 - 12:30 
    Symposium 3: Emerging Clinical importance of iodine
    Supported by Endocrine-Related Cancer and the British Thyroid Foundation
    3B
    Chairs: M Vanderpump (London) & J Waung (London)
    New clinical applications in iodine biology
    11:00
    S3.1
    Iodine nutrition and neurodevelopment
    M Rayman
    11:30
    S3.2
    Regulation of NIS function in thyroid and breast cancer
    G Brent (Los Angeles, USA)
    12:00
    S3.3
    Use of radioiodine in the imaging and therapy of non-thyroidal tumours
    C Spitzweg (Munich, Germany)
    11:00 - 12:30 
    Clinical Management Workshop 2: How do I do it?
    Supported by Endocrinology, Diabetes and Metabolism Case Reports CMW2.1 supported by Hypopara UK
    1A
    Chairs: J Ahlquist (Southend) & C Napier (Newcastle upon Tyne)
    11:00
    CMW2.1
    How do I localise parathyroid tumours?
    D Scott-Coombes
    11:15
    CMW2.2
    How and when do I initiate treatment for central hypothyroidism?
    L Persani (Milan, Italy)
    11:30
    CMW2.3
    How do I manage adrenal replacement in pregnancy?
    W Arlt
    11:45
    CMW2.6
    How do I investigate and manage hyponatraemia?
    S Ball
    12:00
    CMW2.5
    How and when do I treat the older male with a borderline testosterone?
    F Wu
    12:15
    CMW2.4
    How do I investigate and manage sweating?
    F Swords
    12:30 - 13:45 
    Lunch
    Hall 2A
    12:45 - 13:45 
    Internis Industry Sponsored Satellite Symposia
    Vitamin D – the Dark Truth
    1C
    Chair: A Grosso (London)
    12:45 - 13:05
    Clinical Update on Vitamin D
    S Davies
    13:05 - 13:25
    Shedding light on the Health Economics of Vitamin D
    C Poole
    13:25 - 13:45
    The Dark Truth of Prescribing Unlicensed Vitamin D
    P Feldschreiber
    12:45 - 13:45 
    HRA Pharma Industry Sponsored Satellite Symposia
    Cushing’s syndrome and adrenocortical carcinoma management: are we making progress?
    1B
    Chair: R Feelders (Rotterdam, Netherlands)
    12:45 - 12:50
    Welcome and introduction
    R Feelders (Rotterdam, Netherlands)
    12:50 - 13:00
    Current challenges in the management of Cushing’s syndrome
    A Grossman
    13:00 - 13:20
    Use of Steroidogenesis inhibitors for Cushing’s syndrome. Audit of 13 UK tertiary centres
    John Newell-Price (Sheffield, UK)
    13:20 - 13:35
    Multimodal therapy in the management of advanced ACC
    S Aylwin
    13:35 - 13:45
    Questions and Answers
    13:45 - 15:15 
    Applied Physiology Workshop: A guide to the analysis of energy metabolism
    Supported by Journal of Endocrinology
    1B
    Chairs: G Lavery (Birmingham) & D Macfarlane (Dundee)
    How to assess and quantitate energy usage and interpret the data
    13:45
    APW1.1
    Assessing energy demand in living organisms
    J Nedergaard (Stockholm, Sweden)
    14:15
    APW1.2
    Lipid metabolism: from mice to men?
    S Virtue
    14:45
    APW1.3
    Tracking lipid energy partitioning in human liver
    L Hodson
    13:45 - 15:15 
    Oral Communications 1: Young Endocrinologists' Prize Session
    1A
    Chairs: C McCabe (Birmingham) & S Mirczuk (London)
    13:45
    OC1.1
    The Thr92Ala substitution in deiodonase-2 is associated with increased odds of a sub-optimal IQ score in children with low-normal thyroid function
    P Taylor
    14:00
    OC1.2
    Characterisation of adrenocortical progenitor cells: isolation of mesenchymal stem cell-like cell populations from human adrenal cortex
    E Gan
    14:15
    OC1.3
    Angiogenic factors sFlt1 and PlGF are novel determinants of newborn thyroid (dys)function: the Generation R study
    T Korevaar
    14:30
    OC1.4
    Single molecule analysis of GPCR transactivation reveals oligomeric complexes that regulate signal sensitivity
    Kim Jonas (London, UK)
    14:45
    OC1.5
    Kisspeptin - a novel physiological trigger for oocyte maturation in IVF treatment
    A Abbara
    15:00
    OC1.6
    A loss-of-function mutation in the prolactin receptor (PRLR) causes familial hyperprolactinaemia
    Caroline Gorvin (Birmingham, UK)
    13:45 - 15:15 
    Symposium 4: Putting flesh on the bones
    3B
    Chairs: N Shaw (Birmingham) & S Howles (Oxford)
    Genetic disorders of bone and mineral metabolism
    13:45
    S4.1
    Assessment of abnormalities of skeletal development
    E Kinning
    14:15
    S4.2
    Osteogenesis imperfecta - management beyond childhood
    N Gittoes
    14:45
    S4.3
    Management of hypophosphatemic rickets
    T Carpenter (New Haven, USA)
    15:15 - 15:45 
    Tea & Coffee
    Hall 2A
    15:45 - 17:15 
    Education Workshop 1: Teaching and learning in Endocrinology
    3B
    Chairs: A Crown (Brighton) & H Christian (Oxford)
    15:45
    EW1.1
    Endocrinologists as teachers: integrating teaching and practice in the real world
    K Meeran
    16:05
    EW1.2
    Using technology to enhance your teaching in endocrinology
    S Ball
    16:25
    EW1.3
    Exams, and the future of assessment in medicine. A view from the MRCP(UK)
    J Dacre
    16:45
    EW1.4
    Interprofessional learning through and for multidisciplinary working
    D Freeth
    17:05
    Questions and discussion
    15:45 - 17:15 
    Clinical Management Workshop 1: Management of complex obesity
    Supported by Clinical Endocrinology
    1A
    Chairs: B McGowan (London) & K McCullough (London)
    15:45
    CMW1.1
    Have the new commissioning guidelines for bariatric surgery improved patient's pathways?
    J Barth
    16:15
    CMW1.2
    Medical management of severe obesity
    J Wilding
    16:45
    CMW1.3
    Endocrine and metabolic complications post-bariatric surgery
    Nick Finer (London, United Kingdom)
    15:45 - 17:15 
    Oral Communications 2: Endocrine regulation of cell behaviour
    1B
    Chairs: G Lavery (Birmingham) & G WIllis (Cardiff)
    15:45
    OC2.1
    A novel modulator of cell invasion and metastasis
    R Watkins
    16:00
    OC2.2
    Inhibition of human NET cell proliferation by a peptide identified through phage display screening
    M Stevenson
    16:15
    OC2.3
    A20 confers protection against TRAIL-induced apoptosis in the pancreatic beta-cell
    R Yates
    16:30
    OC2.4
    Influence of glucocorticoid receptor density on development and remodelling of the heart
    R Richardson
    16:45
    OC2.5
    Beta-cells require CFTR for glucose-induced insulin secretion
    J Robinson
    17:00
    OC2.6
    A potential role for food-derived microRNAs in human placental development
    K Timms
    15:45 - 17:15 
    Symposium 5: Endocrine consequences of major trauma
    1C
    Chairs: A Logan (Birmingham) & M Sherlock (Dublin, Ireland)
    Pathophysiological changes associated with injury
    15:45
    S5.1
    Endocrine mechanisms of sarcopenia
    J Lord
    16:15
    S5.2
    Pituitary sequelae of traumatic brain injury
    C Thompson (Dublin, Ireland)
    16:45
    S5.3
    Thyroid hormone economy in critical illness
    A Boelen (Amsterdam, The Netherlands)
    17:25 - 18:25 
    SfE Young Endocrinologists' Prize Lectures
    1A
    Chairs: J Franklyn (Birmingham) & K Chapman (Edinburgh)
    YEP1.1
    Basic Prize Lecture: Sox2+ cells of the postnatal pituitary can differentiate into hormone producing cells in vivo and have tumour-inducing potential
    C Andoniadou
    YEP1.2
    Clinical Prize Lecture: Clinical effects of kisspeptin on reproductive hormone secretion, LH pulsatility and oocyte maturation during IVF treatment
    C Jayasena
    18:25 - 19:15 
    Debate: This house believes Genome Wide Association Studies will have no impact upon clinical endocrinology
    1A
    Chair: B Walker (Edinburgh)
    For:
    S O'Rahilly
    Against:
    M Caulfield
    19:15 - 21:00 
    Welcome Reception
    Hall 2A
    20:15 - 22:00 
    Young Endocrinologists' Social Evening and Quiz
    3AB
Tuesday 25 March 61 sessions
    07:45 - 08:00 
    Breakfast
    07:45 -  
    Registration
    08:00 - 08:45 
    Meet the Expert 1
    Supported by Clinical Endocrinology
    3B
    Chair: J Newell-Price (Sheffield)
    MTE1
    Medical management of Cushing's syndrome
    S Akker
    08:00 - 08:45 
    Meet the Expert 2
    Supported by Clinical Endocrinology
    1A
    Chair: N Gittoes (Birmingham)
    MTE2
    Vitamin D replacement: how much, how often and for whom?
    P Selby
    08:00 - 08:45 
    Meet the Expert 3
    Supported by Clinical Endocrinology and the Klinefelter’s Syndrome Association UK
    1B
    Chair: H Jones (Barnsley)
    MTE3
    Endocrine and non-endocrine management of Klinefelter's Syndrome
    Richard Quinton (Newcastle, UK)
    08:00 - 08:45 
    Meet the Expert 4
    Supported by Clinical Endocrinology
    1C
    Chair: L Heisler (Cambridge)
    MTE4
    Optogenetics illuminates neuroendocrinology
    D Burdakov
    09:00 - 10:30 
    Symposium 6: Thyroid cell biology comes to your clinic
    Supported by Journal of Molecular Endocrinology
    1C
    Chairs: C Spitzweg (Munich, Germany) & V Smith (Birmingham)
    Emerging models of clinical relevance to thyroid disease
    09:00
    S6.1
    Development of functional thyroid tissue from embryonic stem cells
    Sabine Costagliola (Brussels, Belgium)
    09:30
    S6.2
    Factors involved in thyroid gland development and survival
    R Lauro
    10:00
    S6.3
    PBF signalling in thyroid tumourigenesis
    Chris McCabe (UK, Birmingham)
    09:00 - 10:30 
    Clinical Management Workshop 2: How do I do it?
    Supported by Endocrinology, Diabetes and Metabolism Case Reports CMW2.1 supported by Hypopara UK
    1A
    Chairs: J Ahlquist (Southend) & C Napier (Newcastle upon Tyne)
    09:00
    CMW2.1
    How do I localise parathyroid tumours?
    D Scott-Coombes
    09:15
    CMW2.2
    How and when do I initiate treatment for central hypothyroidism?
    L Persani (Milan, Italy)
    09:30
    CMW2.3
    How do I manage adrenal replacement in pregnancy?
    W Arlt
    09:45
    CMW2.4
    How do I investigate and manage sweating?
    F Swords
    10:00
    CMW2.5
    How and when do I treat the older male with a borderline testosterone?
    F Wu
    10:15
    CMW2.6
    How do I investigate and manage hyponatraemia?
    S Ball
    09:00 - 10:30 
    Oral Communications 3: Steroids
    3B
    Chairs: C Cummins (Toronto, Canada) & D Nanus (Birmingham)
    09:00
    OC3.1
    Lack of 11β-hydroxysteroid dehydrogenase type 1 ameliorates the adverse features of Cushing’s syndrome
    S Morgan
    09:15
    OC3.2
    5α-Reductase is a regulator of glucocorticoid action and metabolic phenotype in human liver
    M Nasiri
    09:30
    OC3.3
    The 21-hydroxylase pseudogene may have a role in induction of tolerance to steroidogenic machinery
    A Mitchell
    09:45
    OC3.4
    Pre-receptor glucocorticoid metabolism across human ageing: the impact of gender and menopausal status
    Z Hassan-Smith
    10:00
    OC3.5
    Linking GWAS to gene function - CYP17A1 in hypertension
    L Diver
    10:15
    OC3.6
    Targeting of lysyl oxidase by steroids to reduce peritoneal fibrosis and scarring
    C Harlow
    09:00 - 10:30 
    Symposium 7: Natriuretic peptides: so much more than salt and water
    1B
    Chairs: C McArdle (Bristol) & S Mirczuk (London)
    Novel functions for natriuretic peptides
    09:00
    S7.1
    Guanylyl cyclases in cardiomyopathy
    M Kuhn (Wuerzburg, Germany)
    09:30
    S7.2
    Natriuretic peptides in pituitary development and function
    R Fowkes
    10:00
    S7.3
    Natriuretic peptides in cardiovascular disease
    A Hobbs
    10:30 - 11:00 
    Tea & Coffee
    Hall 2A
    11:00 - 11:30 
    Plenary Lecture 1: Society for Endocrinology Dale Medal Lecture 2013
    1A
    Chair: A Grossman (Oxford)
    PL1
    Nuclear receptors, metabolism and the hunger games
    R Evans (La Jolla, USA)
    11:30 - 12:00 
    Plenary Lecture 2: Society for Endocrinology Dale Medal Lecture 2014
    1A
    Chair: A Grossman (Oxford)
    PL2
    Coactivators: Master Genes for Physiology and Pathology
    B O'Malley (Pittsburg, USA)
    12:00 - 14:00 
    Lunch & poster viewing
    Odd-numbered posters attended 12:00 - 13:00; Even-numbered posters attended 13:00 - 14:00
    Hall 2A
    12:45 - 13:45 
    Ipsen Industry Sponsored Satellite Symposia
    Optimising outcomes for patients with acromegaly and NETs
    3AB
    Chair: A Grossman (Oxford)
    High-dose lanreotide Autogel for treatment-naive patients with acromegaly: the results of the PRIMARYS trial
    J Bevan
    SAGIT – A disease staging tool to personalise patient management for acromegaly
    S Petersenn (Hamburg, Germany)
    New data confirming the beneficial role of lanreotide Autogel in the management of patients with a NET
    Aled Rees (Cardiff, United Kingdom)
    14:00 - 15:30 
    Oral Communications 4: Thyroid and Bone
    1C
    Chairs: K Boelaert (Birmingham) & F Hannan (Liverpool)
    14:00
    OC4.1
    Adaptor protein-2 sigma subunit mutations causing familial hypocalciuric hypercalcaemia type 3 exert dominant-negative effects
    S Howles
    14:15
    OC4.2
    PHOSPHO1: roles beyond skeletal mineralisation
    K Oldknow
    14:30
    OC4.3
    TRα mutation causes a severe and thyroxine-resistant skeletal dysplasia
    J Bassett
    14:45
    OC4.4
    Thyroid hormones stimulate osteoclastogenesis via TRα-dependent actions in osteoblasts
    J Logan
    15:00
    OC4.5
    A mutation in the 5’UTR of GNA11 causes familial hypocalciuric hypercalcemia type 2 (FHH2) due to reduced translational efficiency
    S Howles
    15:15
    OC4.6
    An ENU-induced Tyr265Stop mutation in Polg2 is associated with renal calcification in RCALC2 mice
    Caroline Gorvin (Birmingham, UK)
    14:00 - 15:30 
    Young Endocrinologists' Symposium: Establishing successful collaborations
    1B
    Chairs: A Lansdown (Cardiff) & G Begum (Manchester)
    Making the most of interdisciplinary collaborations and peer-to-peer networking
    14:00
    YE1.1
    What makes a successful collaboration between a basic scientist and a clinician?
    W Arlt
    14:15
    YE1.2
    How do I talk to a bioinformatician/mathematician/engineer?
    C McArdle
    14:30
    YE1.3
    Industrial collaborations - where to start?
    J Piner
    14:45
    YE1.4
    Biobanking – what is it, and how could they be beneficial to me?
    J Tobias
    15:00
    YE1.5
    Peer-to-peer collaborations: Importance of YE groups
    K Chapman
    15:15
    Panel discussion
    14:00 - 15:30 
    Symposium 8: Chronic disease and growth
    3B
    Chairs: F Ahmed (Glasgow) & L Dunford (Leicester)
    Chronic inflammation and growth hormone signalling
    14:00
    S8.1
    Understanding growth hormone action through the growth plate
    Colin Farquharson
    14:30
    S8.2
    Targeting SOCS Proteins to Combat Inflammation
    S Yarwood
    15:00
    S8.3
    Managing abnormalities of growth in chronic disease
    D Simon (Paris, France)
    14:00 - 15:30 
    Symposium 9: MEN1- from molecular pathology to therapies
    Supported by Endocrine-Related Cancer and the Association of Multiple Endocrine Neoplasia Disorders
    1A
    Chairs: J Newell-Price (Sheffield) & G Walls (Oxford)
    Current understanding and future perspectives in MEN1
    14:00
    S9.1
    Current understanding and future perspectives in MEN1
    S Agarwal (Bethesda, USA)
    14:30
    S9.2
    Genetics, pathophysiology and translational models of MEN1
    Raj Thakker (Oxford, United Kingdom)
    15:00
    S9.3
    Practical management of patients with MEN1
    B Skogseid (Uppsala, Sweden)
    15:30 - 16:00 
    Tea & Coffee
    Hall 2A
    16:00 - 16:45 
    Meet the Expert 3 (repeat)
    Supported by Clinical Endocrinology and the Klinefelter’s Syndrome Association UK
    3B
    Chair: H Jones (Barnsley)
    MTE3
    Endocrine and non-endocrine management of Klinefelter's Syndrome (repeat)
    Richard Quinton (Newcastle, UK)
    16:00 - 17:30 
    Oral Communications 5: Pituitary
    1B
    Chairs: J Davies (Manchester) & R Watkins (Birmingham)
    16:00
    OC5.1
    Increased frequency and earlier onset of pituitary tumours in mice deleted for a multiple endocrine neoplasia type 1 (MEN1) allele and null for prolyl hydroxylase domain protein 1 (PHD1) (Men1+/-/Phd1-/-)
    M Stevenson
    16:15
    OC5.2
    Implications of the upregulation of lysine specific demethylase (LSD) 1 in the pathogenesis of pituitary adenomas
    I Thompson
    16:30
    OC5.3
    The Wnt/β-catenin effector Tcf3/TCF7L1 is required for normal hypothalamic-pituitary development and mutation in this gene is associated with congenital hypopituitarism
    C Gaston-Massuet
    16:45
    OC5.4
    GnRH pulse frequency-dependent regulation of ICER, a modulator of FSHβ transcription, is attenuated by MEKI/II blockade
    I Thompson
    17:00
    OC5.5
    Spatio-temporal analysis of prolactin gene transcription dynamics reveals short range co-ordination of lactotroph transcription activity in pituitary tissue
    K Featherstone
    17:15
    OC5.6
    A GH antagonist fusion with GH binding protein is biologically active, shows delayed clearance and inhibits growth in a rabbit model
    I Wilkinson
    16:00 - 17:30 
    Symposium 10: Fat and bone
    Supported by Endocrine Connections and the Klinefelter’s Syndrome Association UK
    1A
    Chairs: P Dimitri (Sheffield) & R Crowley (Birmingham)
    Body composition and bone
    16:00
    S10.1
    Fat and its influence on bone
    J Walsh
    16:30
    S10.2
    Obesity and fractures - what is the inter-relationship?
    J Compston
    17:00
    S10.3
    Energy Deficiency, Amenorrhea and the Skeleton:  Challenges and Therapies
    16:45 - 17:30 
    Meet the Expert 5
    Supported by Clinical Endocrinology
    3B
    Chair: P Trainer (Manchester)
    MTE5
    Pituitary replacement therapy
    P Carroll
    17:40 - 18:10 
    Plenary Lecture 3: Clinical Endocrinology Trust Visiting Professor Lecture
    Supported by Clinical Endocrinology Trust
    1A
    Chair: J Connell (Dundee)
    PL3
    Adrenocortical tumours - from bench to bedside and back
    Bruno Allolio (Würzburg, Germany)
    19:30 -  
    Conference dinner and Awards Ceremony
    07:45 - 08:00 
    Breakfast
    08:00 - 08:45 
    Meet the Expert 5 (repeat)
    Supported by Clinical Endocrinology
    1A
    Chair: P Trainer (Manchester)
    MTE5
    Pituitary replacement therapy (repeat)
    P Carroll
    08:00 - 08:45 
    Meet the Expert 6
    Supported by Clinical Endocrinology
    3B
    Chair: C Brain (London)
    MTE6
    Delayed puberty
    J Blair
    08:00 - 08:45 
    Meet the Expert 7
    Supported by Clinical Endocrinology and the Thyroid Eye Disease Charitable Trust
    1B
    Chair: J Gilbert (London)
    MTE7
    Who should the endocrinologist ask the ophtalmologist to review?
    Daniel Ezra (London, UK)
    08:00 - 08:45 
    Society for Endocrinology Journal Awards
    1C
    Chair: D Ray (Manchester)
    08:00 - 08:09
    JA 1
    Society for Endocrinology Journal Award - Journal of Endocrinology: Mice deficient in PAPP-A show resistance to the development of diabetic nephropathy
    C Conover (Rochester, USA on behalf of the author group)
    08:09 - 08:18
    JA 2
    Society for Endocrinology Journal Award - Journal of Molecular Endocrinology:Thyroid-specific inactivation of KIF3A alters TSH signaling pathway and leads to hypothyroidism
    MC Many (Louvain-la-Neuve, Belgium on behalf of the author group)
    08:18 - 08:27
    JA 3
    Society for Endocrinology Journal Award - Endocrine-Related Cancer: Highly prevalent TERT promoter mutations in aggressive thyroid cancers
    M Xing (Baltimore, USA on behalf of the author group)
    08:27 - 08:36
    JA 4
    Society for Endocrinology Journal Award - Clinical Endocrinology: What predicts adverse outcomes in untreated primary hyperparathyroidism? The Parathyroid Epidemiology and Audit Research Study (PEARS)
    G Leese
    08:36 - 08:45
    JA 5
    Society for Endocrinology Journal Award - Endocrine Connections: PKA regulatory subunit R2B is required for murine and human adipocyte differentiation
    A Spada (Milan, Italy on behalf of the author group)
    08:45 - 09:25 
    Society for Endocrinology AGM
    1A
    09:30 - 11:00 
    Education Workshop 2: Practical publishing advice
    3B
    Chair: D Ray (Manchester)
    09:30
    EW2.1
    Introduction
    D Ray
    09:35
    EW2.2
    Publishing ethics: Fabrication, Falsification and Plagiarism
    A Clark
    09:45
    EW2.3
    The peer review process
    C Høybye (Stockholm, Sweden)
    09:55
    EW2.4
    Writing an attention grabbing abstract
    F Weber (Essen, Germany)
    10:05
    EW2.5
    Responding to reviewer comments
    S Ball
    10:15
    EW2.6
    The art of scientific writing
    Maralyn Druce (London, UK)
    10:25
    EW2.7
    Open Access
    L Flook
    10:35
    Questions and discussion
    09:30 - 11:00 
    Nurse Session 1 - Cushing's Syndrome
    1B
    Chairs: N Kieffer (Leicester) & J Andrew (Leeds)
    09:30
    N1.1
    Investigating and Diagnosing Cushing’s Syndrome -not as straightforward as it seems?
    K Meeran
    09:55
    N1.2
    The role of the Endocrine Nurse in the Management of patients with Cushing’s syndrome
    W Geilvoet (Rotterdam, The Netherlands)
    10:20
    N1.3
    Why do ‘cured’ Cushing’s patients need long-term follow up?
    S Webb (Barcelona, Spain)
    10:45
    N1.4
    Cushing’s patient experience
    A Patrick
    09:30 - 11:00 
    Symposium 11: Some like it hot - new insights into brown adipose tissue
    1C
    Chairs: S O'Rahilly (Cambridge) & S Virtue (Cambridge)
    Emerging biology of brown adipose tissue
    09:30
    S11.1
    Mechanisms of brown adipocyte determination
    P Seale (Philadelphia, USA)
    10:00
    S11.2
    The metabolic capacities of brown adipose tissue
    B Cannon (Stockholm, Sweden)
    10:30
    S11.3
    How brown is human brown adipose tissue?
    S Enerback (Gothenburg, Sweden)
    09:30 - 11:00 
    Clinical Management Workshop 3: Improving the care of young people in endocrinology
    Supported by Clinical Endocrinology
    1A
    Chairs: H Gleeson (Leicester) & R El-Khairi (London)
    09:30
    CMW3.1
    Adolescent health care in the UK in 2014
    B White
    10:00
    CMW3.2
    Adrenal replacement in adolescents and young adults
    P Hindmarsh (London, UK)
    10:30
    CMW3.3
    Optimising bone health in adolescents and young adults
    N Shaw (Birmingham, UK)
    11:00 - 11:30 
    Tea & Coffee
    Exhibtion Hall
    11:30 - 12:00 
    Plenary Lecture 4: Society for Endocrinology European Medal Lecture
    1A
    Chair: G Williams (London)
    PL4
    Mechanisms of thyroid hormone resistance
    T Visser (Rotterdam, Netherlands)
    12:00 - 12:30 
    Plenary Lecture 5: Society for Endocrinology Transatlantic Medal Lecture
    1A
    Chair: D Ray (Manchester)
    PL5
    Transcriptional Coordination of Circadian and Metabolic Physiology
    M Lazar (Philadelphia, USA)
    12:30 - 13:45 
    Lunch & poster viewing
    Shortlisted posters attended
    Hall 2A
    12:45 - 13:45 
    Viropharma Industry Sponsored Satellite Symposia
    New insights in the management of Adrenal Insufficiency in the UK
    3AB
    Chair: S Pearce (Newcastle-Upon-Tyne)
    12:45 - 12:55
    Introduction: The unmet medical need in adrenal insufficiency and the importance of circadian rhythm
    S Pearce (Newcastle, UK)
    12:55 - 13:10
    Adrenal Insufficiency today: the Salford project
    P Trainer
    13:10 - 13:25
    Adrenal Insufficiency today: a report from the EU-AIR registry
    Robert Murray (Leeds, UK)
    13:25 - 13:40
    Patient cases and physician experience
    R Pivonello (Naples, Italy)
    13:40 - 13:45
    Closing remarks
    S Pearce (Newcastle, UK)
    13:45 - 14:30 
    Meet the Expert 8
    1C
    Chair: C McCabe (Birmingham)
    MTE8
    Growing organs in the lab
    A Mel
    13:45 - 15:15 
    Nurses Session 2: The journey of endocrine nursing research: from evidence based practice to independent research
    1B
    Chairs: L Shephard (Birmingham) & V Fazal-Sanderson (Oxford)
    13:45
    N2.1
    Background on the journey of endocrine nursing research
    L Shepherd
    13:50
    N2.2
    How to audit and evaluate your own practice
    J Munday
    14:15
    N2.3
    The role of the endocrine nurse in clinical trials
    A Marland
    14:40
    N2.4
    Independent nursing research
    S Llahana
    15:05
    Questions and discussion
    13:45 - 15:15 
    Symposium 12: Getting excited about sugar - the brain and blood glucose control
    Supported by Endocrine Connections
    1A
    Chairs: R McCrimmon (Dundee) & B Challis (Cambridge)
    How the brain orchestrates glucose metabolism
    13:45
    S12.1
    How the brain senses blood glucose
    M Evans
    14:15
    S12.2
    Vagal control of energy metabolism
    S Trapp
    14:45
    S12.3
    Does glucagon need the brain for its effects on blood glucose?
    R McCrimmon
    13:45 - 15:15 
    Oral Communications 6: Clinical
    3B
    Chairs: R Semple (Cambridge) & A Puttanna (Walsall)
    13:45
    OC6.1
    Adverse outcome in glucocorticoid-induced adrenal suppression; an analysis of short synacthen tests in 2782 patients
    M Chapman
    14:00
    OC6.2
    Localising parathyroid adenomas. Which imaging modality is best? Pre-operative localisation studies in patients with primary hyperparathyroidism: a large audit in a London tertiary centre
    D Lewis
    14:15
    OC6.3
    Sirolimus therapy for a patient with segmental overgrowth due to a mosaic activating mutation in phosphatidylinositol-3-kinase (PI3K)
    V Parker
    14:30
    OC6.4
    Reduced cognitive performance and altered white matter microstructure in young insulin-resistant women with polycystic ovary syndrome
    M Udiawar
    14:45
    OC6.5
    Effectiveness of metyrapone in 195 patients with Cushing’s syndrome
    E Daniel
    15:00
    OC6.6
    11C-Methionine PET-CT co-registered with volume MRI: a novel adjunctive imaging modality to aid diagnosis and management in patients with pituitary adenomas
    O Koulouri
    14:30 - 15:15 
    Meet the Expert 9
    1C
    Chairs: H Turner (Oxford) & P Hadoke (Edinburgh)
    MTE9
    Novel techniques to assess angiogenesis
    S Germain (Paris, France)
    15:15 - 15:45 
    Tea & Coffee
    Hall 2A
    15:45 - 16:15 
    Oral Communication and Poster Prize Ceremony
    1A
    Chairs: A Grossman (Oxford) & C McCabe (Birmingham)
    16:15 - 16:45 
    Plenary Lecture 6: British Tyroid Association Pitt-Rivers Lecture
    Supported by Clinical Endocrinology Trust
    1A
    Chair: G Williams (London)
    PL6
    Disorders of thyroid hormone action: insights from human genetics
    Krishna Chatterjee (Cambridge, UK)
    16:45 - 17:15 
    Plenary Lecture 7: Society for Endocrinology Medal Lecture
    1A
    Chair: D Ray (Manchester)
    PL7
    The clock in the pituitary gland: timing annual cycles
    A Loudon
    07:45 - 08:00 
    Breakfast
    08:00 - 08:45 
    Meet the Expert 1 (repeat)
    Supported by Clinical Endocrinology
    1B
    Chair: J Newell-Price (Sheffield)
    MTE1
    Medical management of Cushing's syndrome (repeat)
    S Akker
    08:00 - 08:45 
    Meet the Expert 2 (repeat)
    Supported by Clinical Endocrinology
    1C
    Chair: N Gittoes (Birmingham)
    MTE2
    Vitamin D replacement: how much, how often and for whom? (repeat)
    P Selby
    08:45 - 09:15 
    Plenary Lecture 8: Clinical Endocrinology Trust Lecture
    Supported by the Clinical Endocrinology Trust
    1A
    Chair: JS Bevan (Aberdeen)
    PL8
    Understanding glucocorticoid action, and the role of the glucocorticoid receptor
    D Ray
    09:15 - 09:45 
    Plenary Lecture 9: Society for Endocrinology Hoffenberg International Medal Lecture
    1A
    Chair: C McCabe (Birmingham)
    PL9
    Male Fertility Regulation; achievements and frustrations
    R McLachlan (Clayton, Australia)
    09:45 - 10:15 
    Society for Endocrinology Emergency Endocrine Guidance
    1A
    Chair: J Franklyn (Birmingham)
    SFE1.1
    Acute Hypercalcaemia and Acute Hypocalcaemia
    James Turner (UK)
    SFE1.2
    Pituitary Apoplexy
    S Baldeweg
    10:15 - 10:45 
    Tea & Coffee
    3AB
    10:45 - 11:30 
    Meet the Expert 6 (repeat)
    1B
    Chair: C Brain (London)
    MTE6
    Delayed puberty (repeat)
    J Blair
    10:45 - 12:15 
    Clinical Management Workshop 4: Cardiovascular risk in endocrine disease
    Supported by Endocrinology, Diabetes & Metabolism Case Reports and the Turner Syndrome Support Society
    1A
    Chairs: A Bates (Stourbridge) & J Thomas (Taunton)
    10:45
    CMW4.1
    Cardiovascular risk in Turner's syndrome
    M Donaldson
    11:15
    CMW4.2
    Valvular disease in prolactinomas- weighing up the evidence
    William Drake (London, UK)
    11:45
    CMW4.3
    Cardiovascular risk in childhood cancer survivors
    E Crowne
    10:45 - 12:45 
    Senior Endocrinologists' Session
    1C
    Chairs: B Cooke (Harpenden) & P Belchetz (Wetherby)
    10:45
    SE1.4
    The Foundling Hospital
    B Cooke
    11:09
    SE1.2
    1776 Revolution in Liverpool. Matthew Dobson discovers Hyperglycaemia!
    I MacFarlane
    11:33
    SE1.3
    Macroprolacin - To seek or ignore : a Trans-Atlantic Divide
    J McKenna (Dublin, Ireland)
    11:57
    SE1.1
    How important is luck for major discoveries?
    J Tata
    12:21
    SE1.5
    Steroid Merchants of Edinburgh
    I Mason
    11:30 - 12:15 
    Meet the Expert 7 (repeat)
    Supported by Clinical Endocrinology and the Thyroid Eye Disease Charitable Trust
    1B
    Chair: J Gilbert (London)
    MTE7
    Whom should the endocrinologist ask the ophtalmologist to review? (repeat)
    Daniel Ezra (London, UK)
Wednesday 26 March 61 sessions
    07:45 - 08:00 
    Breakfast
    07:45 -  
    Registration
    08:00 - 08:45 
    Meet the Expert 1
    Supported by Clinical Endocrinology
    3B
    Chair: J Newell-Price (Sheffield)
    MTE1
    Medical management of Cushing's syndrome
    S Akker
    08:00 - 08:45 
    Meet the Expert 2
    Supported by Clinical Endocrinology
    1A
    Chair: N Gittoes (Birmingham)
    MTE2
    Vitamin D replacement: how much, how often and for whom?
    P Selby
    08:00 - 08:45 
    Meet the Expert 3
    Supported by Clinical Endocrinology and the Klinefelter’s Syndrome Association UK
    1B
    Chair: H Jones (Barnsley)
    MTE3
    Endocrine and non-endocrine management of Klinefelter's Syndrome
    Richard Quinton (Newcastle, UK)
    08:00 - 08:45 
    Meet the Expert 4
    Supported by Clinical Endocrinology
    1C
    Chair: L Heisler (Cambridge)
    MTE4
    Optogenetics illuminates neuroendocrinology
    D Burdakov
    09:00 - 10:30 
    Symposium 6: Thyroid cell biology comes to your clinic
    Supported by Journal of Molecular Endocrinology
    1C
    Chairs: C Spitzweg (Munich, Germany) & V Smith (Birmingham)
    Emerging models of clinical relevance to thyroid disease
    09:00
    S6.1
    Development of functional thyroid tissue from embryonic stem cells
    Sabine Costagliola (Brussels, Belgium)
    09:30
    S6.2
    Factors involved in thyroid gland development and survival
    R Lauro
    10:00
    S6.3
    PBF signalling in thyroid tumourigenesis
    Chris McCabe (UK, Birmingham)
    09:00 - 10:30 
    Clinical Management Workshop 2: How do I do it?
    Supported by Endocrinology, Diabetes and Metabolism Case Reports CMW2.1 supported by Hypopara UK
    1A
    Chairs: J Ahlquist (Southend) & C Napier (Newcastle upon Tyne)
    09:00
    CMW2.1
    How do I localise parathyroid tumours?
    D Scott-Coombes
    09:15
    CMW2.2
    How and when do I initiate treatment for central hypothyroidism?
    L Persani (Milan, Italy)
    09:30
    CMW2.3
    How do I manage adrenal replacement in pregnancy?
    W Arlt
    09:45
    CMW2.4
    How do I investigate and manage sweating?
    F Swords
    10:00
    CMW2.5
    How and when do I treat the older male with a borderline testosterone?
    F Wu
    10:15
    CMW2.6
    How do I investigate and manage hyponatraemia?
    S Ball
    09:00 - 10:30 
    Oral Communications 3: Steroids
    3B
    Chairs: C Cummins (Toronto, Canada) & D Nanus (Birmingham)
    09:00
    OC3.1
    Lack of 11β-hydroxysteroid dehydrogenase type 1 ameliorates the adverse features of Cushing’s syndrome
    S Morgan
    09:15
    OC3.2
    5α-Reductase is a regulator of glucocorticoid action and metabolic phenotype in human liver
    M Nasiri
    09:30
    OC3.3
    The 21-hydroxylase pseudogene may have a role in induction of tolerance to steroidogenic machinery
    A Mitchell
    09:45
    OC3.4
    Pre-receptor glucocorticoid metabolism across human ageing: the impact of gender and menopausal status
    Z Hassan-Smith
    10:00
    OC3.5
    Linking GWAS to gene function - CYP17A1 in hypertension
    L Diver
    10:15
    OC3.6
    Targeting of lysyl oxidase by steroids to reduce peritoneal fibrosis and scarring
    C Harlow
    09:00 - 10:30 
    Symposium 7: Natriuretic peptides: so much more than salt and water
    1B
    Chairs: C McArdle (Bristol) & S Mirczuk (London)
    Novel functions for natriuretic peptides
    09:00
    S7.1
    Guanylyl cyclases in cardiomyopathy
    M Kuhn (Wuerzburg, Germany)
    09:30
    S7.2
    Natriuretic peptides in pituitary development and function
    R Fowkes
    10:00
    S7.3
    Natriuretic peptides in cardiovascular disease
    A Hobbs
    10:30 - 11:00 
    Tea & Coffee
    Hall 2A
    11:00 - 11:30 
    Plenary Lecture 1: Society for Endocrinology Dale Medal Lecture 2013
    1A
    Chair: A Grossman (Oxford)
    PL1
    Nuclear receptors, metabolism and the hunger games
    R Evans (La Jolla, USA)
    11:30 - 12:00 
    Plenary Lecture 2: Society for Endocrinology Dale Medal Lecture 2014
    1A
    Chair: A Grossman (Oxford)
    PL2
    Coactivators: Master Genes for Physiology and Pathology
    B O'Malley (Pittsburg, USA)
    12:00 - 14:00 
    Lunch & poster viewing
    Odd-numbered posters attended 12:00 - 13:00; Even-numbered posters attended 13:00 - 14:00
    Hall 2A
    12:45 - 13:45 
    Ipsen Industry Sponsored Satellite Symposia
    Optimising outcomes for patients with acromegaly and NETs
    3AB
    Chair: A Grossman (Oxford)
    High-dose lanreotide Autogel for treatment-naive patients with acromegaly: the results of the PRIMARYS trial
    J Bevan
    SAGIT – A disease staging tool to personalise patient management for acromegaly
    S Petersenn (Hamburg, Germany)
    New data confirming the beneficial role of lanreotide Autogel in the management of patients with a NET
    Aled Rees (Cardiff, United Kingdom)
    14:00 - 15:30 
    Oral Communications 4: Thyroid and Bone
    1C
    Chairs: K Boelaert (Birmingham) & F Hannan (Liverpool)
    14:00
    OC4.1
    Adaptor protein-2 sigma subunit mutations causing familial hypocalciuric hypercalcaemia type 3 exert dominant-negative effects
    S Howles
    14:15
    OC4.2
    PHOSPHO1: roles beyond skeletal mineralisation
    K Oldknow
    14:30
    OC4.3
    TRα mutation causes a severe and thyroxine-resistant skeletal dysplasia
    J Bassett
    14:45
    OC4.4
    Thyroid hormones stimulate osteoclastogenesis via TRα-dependent actions in osteoblasts
    J Logan
    15:00
    OC4.5
    A mutation in the 5’UTR of GNA11 causes familial hypocalciuric hypercalcemia type 2 (FHH2) due to reduced translational efficiency
    S Howles
    15:15
    OC4.6
    An ENU-induced Tyr265Stop mutation in Polg2 is associated with renal calcification in RCALC2 mice
    Caroline Gorvin (Birmingham, UK)
    14:00 - 15:30 
    Young Endocrinologists' Symposium: Establishing successful collaborations
    1B
    Chairs: A Lansdown (Cardiff) & G Begum (Manchester)
    Making the most of interdisciplinary collaborations and peer-to-peer networking
    14:00
    YE1.1
    What makes a successful collaboration between a basic scientist and a clinician?
    W Arlt
    14:15
    YE1.2
    How do I talk to a bioinformatician/mathematician/engineer?
    C McArdle
    14:30
    YE1.3
    Industrial collaborations - where to start?
    J Piner
    14:45
    YE1.4
    Biobanking – what is it, and how could they be beneficial to me?
    J Tobias
    15:00
    YE1.5
    Peer-to-peer collaborations: Importance of YE groups
    K Chapman
    15:15
    Panel discussion
    14:00 - 15:30 
    Symposium 8: Chronic disease and growth
    3B
    Chairs: F Ahmed (Glasgow) & L Dunford (Leicester)
    Chronic inflammation and growth hormone signalling
    14:00
    S8.1
    Understanding growth hormone action through the growth plate
    Colin Farquharson
    14:30
    S8.2
    Targeting SOCS Proteins to Combat Inflammation
    S Yarwood
    15:00
    S8.3
    Managing abnormalities of growth in chronic disease
    D Simon (Paris, France)
    14:00 - 15:30 
    Symposium 9: MEN1- from molecular pathology to therapies
    Supported by Endocrine-Related Cancer and the Association of Multiple Endocrine Neoplasia Disorders
    1A
    Chairs: J Newell-Price (Sheffield) & G Walls (Oxford)
    Current understanding and future perspectives in MEN1
    14:00
    S9.1
    Current understanding and future perspectives in MEN1
    S Agarwal (Bethesda, USA)
    14:30
    S9.2
    Genetics, pathophysiology and translational models of MEN1
    Raj Thakker (Oxford, United Kingdom)
    15:00
    S9.3
    Practical management of patients with MEN1
    B Skogseid (Uppsala, Sweden)
    15:30 - 16:00 
    Tea & Coffee
    Hall 2A
    16:00 - 16:45 
    Meet the Expert 3 (repeat)
    Supported by Clinical Endocrinology and the Klinefelter’s Syndrome Association UK
    3B
    Chair: H Jones (Barnsley)
    MTE3
    Endocrine and non-endocrine management of Klinefelter's Syndrome (repeat)
    Richard Quinton (Newcastle, UK)
    16:00 - 17:30 
    Oral Communications 5: Pituitary
    1B
    Chairs: J Davies (Manchester) & R Watkins (Birmingham)
    16:00
    OC5.1
    Increased frequency and earlier onset of pituitary tumours in mice deleted for a multiple endocrine neoplasia type 1 (MEN1) allele and null for prolyl hydroxylase domain protein 1 (PHD1) (Men1+/-/Phd1-/-)
    M Stevenson
    16:15
    OC5.2
    Implications of the upregulation of lysine specific demethylase (LSD) 1 in the pathogenesis of pituitary adenomas
    I Thompson
    16:30
    OC5.3
    The Wnt/β-catenin effector Tcf3/TCF7L1 is required for normal hypothalamic-pituitary development and mutation in this gene is associated with congenital hypopituitarism
    C Gaston-Massuet
    16:45
    OC5.4
    GnRH pulse frequency-dependent regulation of ICER, a modulator of FSHβ transcription, is attenuated by MEKI/II blockade
    I Thompson
    17:00
    OC5.5
    Spatio-temporal analysis of prolactin gene transcription dynamics reveals short range co-ordination of lactotroph transcription activity in pituitary tissue
    K Featherstone
    17:15
    OC5.6
    A GH antagonist fusion with GH binding protein is biologically active, shows delayed clearance and inhibits growth in a rabbit model
    I Wilkinson
    16:00 - 17:30 
    Symposium 10: Fat and bone
    Supported by Endocrine Connections and the Klinefelter’s Syndrome Association UK
    1A
    Chairs: P Dimitri (Sheffield) & R Crowley (Birmingham)
    Body composition and bone
    16:00
    S10.1
    Fat and its influence on bone
    J Walsh
    16:30
    S10.2
    Obesity and fractures - what is the inter-relationship?
    J Compston
    17:00
    S10.3
    Energy Deficiency, Amenorrhea and the Skeleton:  Challenges and Therapies
    16:45 - 17:30 
    Meet the Expert 5
    Supported by Clinical Endocrinology
    3B
    Chair: P Trainer (Manchester)
    MTE5
    Pituitary replacement therapy
    P Carroll
    17:40 - 18:10 
    Plenary Lecture 3: Clinical Endocrinology Trust Visiting Professor Lecture
    Supported by Clinical Endocrinology Trust
    1A
    Chair: J Connell (Dundee)
    PL3
    Adrenocortical tumours - from bench to bedside and back
    Bruno Allolio (Würzburg, Germany)
    19:30 -  
    Conference dinner and Awards Ceremony
    07:45 - 08:00 
    Breakfast
    08:00 - 08:45 
    Meet the Expert 5 (repeat)
    Supported by Clinical Endocrinology
    1A
    Chair: P Trainer (Manchester)
    MTE5
    Pituitary replacement therapy (repeat)
    P Carroll
    08:00 - 08:45 
    Meet the Expert 6
    Supported by Clinical Endocrinology
    3B
    Chair: C Brain (London)
    MTE6
    Delayed puberty
    J Blair
    08:00 - 08:45 
    Meet the Expert 7
    Supported by Clinical Endocrinology and the Thyroid Eye Disease Charitable Trust
    1B
    Chair: J Gilbert (London)
    MTE7
    Who should the endocrinologist ask the ophtalmologist to review?
    Daniel Ezra (London, UK)
    08:00 - 08:45 
    Society for Endocrinology Journal Awards
    1C
    Chair: D Ray (Manchester)
    08:00 - 08:09
    JA 1
    Society for Endocrinology Journal Award - Journal of Endocrinology: Mice deficient in PAPP-A show resistance to the development of diabetic nephropathy
    C Conover (Rochester, USA on behalf of the author group)
    08:09 - 08:18
    JA 2
    Society for Endocrinology Journal Award - Journal of Molecular Endocrinology:Thyroid-specific inactivation of KIF3A alters TSH signaling pathway and leads to hypothyroidism
    MC Many (Louvain-la-Neuve, Belgium on behalf of the author group)
    08:18 - 08:27
    JA 3
    Society for Endocrinology Journal Award - Endocrine-Related Cancer: Highly prevalent TERT promoter mutations in aggressive thyroid cancers
    M Xing (Baltimore, USA on behalf of the author group)
    08:27 - 08:36
    JA 4
    Society for Endocrinology Journal Award - Clinical Endocrinology: What predicts adverse outcomes in untreated primary hyperparathyroidism? The Parathyroid Epidemiology and Audit Research Study (PEARS)
    G Leese
    08:36 - 08:45
    JA 5
    Society for Endocrinology Journal Award - Endocrine Connections: PKA regulatory subunit R2B is required for murine and human adipocyte differentiation
    A Spada (Milan, Italy on behalf of the author group)
    08:45 - 09:25 
    Society for Endocrinology AGM
    1A
    09:30 - 11:00 
    Education Workshop 2: Practical publishing advice
    3B
    Chair: D Ray (Manchester)
    09:30
    EW2.1
    Introduction
    D Ray
    09:35
    EW2.2
    Publishing ethics: Fabrication, Falsification and Plagiarism
    A Clark
    09:45
    EW2.3
    The peer review process
    C Høybye (Stockholm, Sweden)
    09:55
    EW2.4
    Writing an attention grabbing abstract
    F Weber (Essen, Germany)
    10:05
    EW2.5
    Responding to reviewer comments
    S Ball
    10:15
    EW2.6
    The art of scientific writing
    Maralyn Druce (London, UK)
    10:25
    EW2.7
    Open Access
    L Flook
    10:35
    Questions and discussion
    09:30 - 11:00 
    Nurse Session 1 - Cushing's Syndrome
    1B
    Chairs: N Kieffer (Leicester) & J Andrew (Leeds)
    09:30
    N1.1
    Investigating and Diagnosing Cushing’s Syndrome -not as straightforward as it seems?
    K Meeran
    09:55
    N1.2
    The role of the Endocrine Nurse in the Management of patients with Cushing’s syndrome
    W Geilvoet (Rotterdam, The Netherlands)
    10:20
    N1.3
    Why do ‘cured’ Cushing’s patients need long-term follow up?
    S Webb (Barcelona, Spain)
    10:45
    N1.4
    Cushing’s patient experience
    A Patrick
    09:30 - 11:00 
    Symposium 11: Some like it hot - new insights into brown adipose tissue
    1C
    Chairs: S O'Rahilly (Cambridge) & S Virtue (Cambridge)
    Emerging biology of brown adipose tissue
    09:30
    S11.1
    Mechanisms of brown adipocyte determination
    P Seale (Philadelphia, USA)
    10:00
    S11.2
    The metabolic capacities of brown adipose tissue
    B Cannon (Stockholm, Sweden)
    10:30
    S11.3
    How brown is human brown adipose tissue?
    S Enerback (Gothenburg, Sweden)
    09:30 - 11:00 
    Clinical Management Workshop 3: Improving the care of young people in endocrinology
    Supported by Clinical Endocrinology
    1A
    Chairs: H Gleeson (Leicester) & R El-Khairi (London)
    09:30
    CMW3.1
    Adolescent health care in the UK in 2014
    B White
    10:00
    CMW3.2
    Adrenal replacement in adolescents and young adults
    P Hindmarsh (London, UK)
    10:30
    CMW3.3
    Optimising bone health in adolescents and young adults
    N Shaw (Birmingham, UK)
    11:00 - 11:30 
    Tea & Coffee
    Exhibtion Hall
    11:30 - 12:00 
    Plenary Lecture 4: Society for Endocrinology European Medal Lecture
    1A
    Chair: G Williams (London)
    PL4
    Mechanisms of thyroid hormone resistance
    T Visser (Rotterdam, Netherlands)
    12:00 - 12:30 
    Plenary Lecture 5: Society for Endocrinology Transatlantic Medal Lecture
    1A
    Chair: D Ray (Manchester)
    PL5
    Transcriptional Coordination of Circadian and Metabolic Physiology
    M Lazar (Philadelphia, USA)
    12:30 - 13:45 
    Lunch & poster viewing
    Shortlisted posters attended
    Hall 2A
    12:45 - 13:45 
    Viropharma Industry Sponsored Satellite Symposia
    New insights in the management of Adrenal Insufficiency in the UK
    3AB
    Chair: S Pearce (Newcastle-Upon-Tyne)
    12:45 - 12:55
    Introduction: The unmet medical need in adrenal insufficiency and the importance of circadian rhythm
    S Pearce (Newcastle, UK)
    12:55 - 13:10
    Adrenal Insufficiency today: the Salford project
    P Trainer
    13:10 - 13:25
    Adrenal Insufficiency today: a report from the EU-AIR registry
    Robert Murray (Leeds, UK)
    13:25 - 13:40
    Patient cases and physician experience
    R Pivonello (Naples, Italy)
    13:40 - 13:45
    Closing remarks
    S Pearce (Newcastle, UK)
    13:45 - 14:30 
    Meet the Expert 8
    1C
    Chair: C McCabe (Birmingham)
    MTE8
    Growing organs in the lab
    A Mel
    13:45 - 15:15 
    Nurses Session 2: The journey of endocrine nursing research: from evidence based practice to independent research
    1B
    Chairs: L Shephard (Birmingham) & V Fazal-Sanderson (Oxford)
    13:45
    N2.1
    Background on the journey of endocrine nursing research
    L Shepherd
    13:50
    N2.2
    How to audit and evaluate your own practice
    J Munday
    14:15
    N2.3
    The role of the endocrine nurse in clinical trials
    A Marland
    14:40
    N2.4
    Independent nursing research
    S Llahana
    15:05
    Questions and discussion
    13:45 - 15:15 
    Symposium 12: Getting excited about sugar - the brain and blood glucose control
    Supported by Endocrine Connections
    1A
    Chairs: R McCrimmon (Dundee) & B Challis (Cambridge)
    How the brain orchestrates glucose metabolism
    13:45
    S12.1
    How the brain senses blood glucose
    M Evans
    14:15
    S12.2
    Vagal control of energy metabolism
    S Trapp
    14:45
    S12.3
    Does glucagon need the brain for its effects on blood glucose?
    R McCrimmon
    13:45 - 15:15 
    Oral Communications 6: Clinical
    3B
    Chairs: R Semple (Cambridge) & A Puttanna (Walsall)
    13:45
    OC6.1
    Adverse outcome in glucocorticoid-induced adrenal suppression; an analysis of short synacthen tests in 2782 patients
    M Chapman
    14:00
    OC6.2
    Localising parathyroid adenomas. Which imaging modality is best? Pre-operative localisation studies in patients with primary hyperparathyroidism: a large audit in a London tertiary centre
    D Lewis
    14:15
    OC6.3
    Sirolimus therapy for a patient with segmental overgrowth due to a mosaic activating mutation in phosphatidylinositol-3-kinase (PI3K)
    V Parker
    14:30
    OC6.4
    Reduced cognitive performance and altered white matter microstructure in young insulin-resistant women with polycystic ovary syndrome
    M Udiawar
    14:45
    OC6.5
    Effectiveness of metyrapone in 195 patients with Cushing’s syndrome
    E Daniel
    15:00
    OC6.6
    11C-Methionine PET-CT co-registered with volume MRI: a novel adjunctive imaging modality to aid diagnosis and management in patients with pituitary adenomas
    O Koulouri
    14:30 - 15:15 
    Meet the Expert 9
    1C
    Chairs: H Turner (Oxford) & P Hadoke (Edinburgh)
    MTE9
    Novel techniques to assess angiogenesis
    S Germain (Paris, France)
    15:15 - 15:45 
    Tea & Coffee
    Hall 2A
    15:45 - 16:15 
    Oral Communication and Poster Prize Ceremony
    1A
    Chairs: A Grossman (Oxford) & C McCabe (Birmingham)
    16:15 - 16:45 
    Plenary Lecture 6: British Tyroid Association Pitt-Rivers Lecture
    Supported by Clinical Endocrinology Trust
    1A
    Chair: G Williams (London)
    PL6
    Disorders of thyroid hormone action: insights from human genetics
    Krishna Chatterjee (Cambridge, UK)
    16:45 - 17:15 
    Plenary Lecture 7: Society for Endocrinology Medal Lecture
    1A
    Chair: D Ray (Manchester)
    PL7
    The clock in the pituitary gland: timing annual cycles
    A Loudon
    07:45 - 08:00 
    Breakfast
    08:00 - 08:45 
    Meet the Expert 1 (repeat)
    Supported by Clinical Endocrinology
    1B
    Chair: J Newell-Price (Sheffield)
    MTE1
    Medical management of Cushing's syndrome (repeat)
    S Akker
    08:00 - 08:45 
    Meet the Expert 2 (repeat)
    Supported by Clinical Endocrinology
    1C
    Chair: N Gittoes (Birmingham)
    MTE2
    Vitamin D replacement: how much, how often and for whom? (repeat)
    P Selby
    08:45 - 09:15 
    Plenary Lecture 8: Clinical Endocrinology Trust Lecture
    Supported by the Clinical Endocrinology Trust
    1A
    Chair: JS Bevan (Aberdeen)
    PL8
    Understanding glucocorticoid action, and the role of the glucocorticoid receptor
    D Ray
    09:15 - 09:45 
    Plenary Lecture 9: Society for Endocrinology Hoffenberg International Medal Lecture
    1A
    Chair: C McCabe (Birmingham)
    PL9
    Male Fertility Regulation; achievements and frustrations
    R McLachlan (Clayton, Australia)
    09:45 - 10:15 
    Society for Endocrinology Emergency Endocrine Guidance
    1A
    Chair: J Franklyn (Birmingham)
    SFE1.1
    Acute Hypercalcaemia and Acute Hypocalcaemia
    James Turner (UK)
    SFE1.2
    Pituitary Apoplexy
    S Baldeweg
    10:15 - 10:45 
    Tea & Coffee
    3AB
    10:45 - 11:30 
    Meet the Expert 6 (repeat)
    1B
    Chair: C Brain (London)
    MTE6
    Delayed puberty (repeat)
    J Blair
    10:45 - 12:15 
    Clinical Management Workshop 4: Cardiovascular risk in endocrine disease
    Supported by Endocrinology, Diabetes & Metabolism Case Reports and the Turner Syndrome Support Society
    1A
    Chairs: A Bates (Stourbridge) & J Thomas (Taunton)
    10:45
    CMW4.1
    Cardiovascular risk in Turner's syndrome
    M Donaldson
    11:15
    CMW4.2
    Valvular disease in prolactinomas- weighing up the evidence
    William Drake (London, UK)
    11:45
    CMW4.3
    Cardiovascular risk in childhood cancer survivors
    E Crowne
    10:45 - 12:45 
    Senior Endocrinologists' Session
    1C
    Chairs: B Cooke (Harpenden) & P Belchetz (Wetherby)
    10:45
    SE1.4
    The Foundling Hospital
    B Cooke
    11:09
    SE1.2
    1776 Revolution in Liverpool. Matthew Dobson discovers Hyperglycaemia!
    I MacFarlane
    11:33
    SE1.3
    Macroprolacin - To seek or ignore : a Trans-Atlantic Divide
    J McKenna (Dublin, Ireland)
    11:57
    SE1.1
    How important is luck for major discoveries?
    J Tata
    12:21
    SE1.5
    Steroid Merchants of Edinburgh
    I Mason
    11:30 - 12:15 
    Meet the Expert 7 (repeat)
    Supported by Clinical Endocrinology and the Thyroid Eye Disease Charitable Trust
    1B
    Chair: J Gilbert (London)
    MTE7
    Whom should the endocrinologist ask the ophtalmologist to review? (repeat)
    Daniel Ezra (London, UK)
Thursday 27 March 61 sessions
    07:45 - 08:00 
    Breakfast
    07:45 -  
    Registration
    08:00 - 08:45 
    Meet the Expert 1
    Supported by Clinical Endocrinology
    3B
    Chair: J Newell-Price (Sheffield)
    MTE1
    Medical management of Cushing's syndrome
    S Akker
    08:00 - 08:45 
    Meet the Expert 2
    Supported by Clinical Endocrinology
    1A
    Chair: N Gittoes (Birmingham)
    MTE2
    Vitamin D replacement: how much, how often and for whom?
    P Selby
    08:00 - 08:45 
    Meet the Expert 3
    Supported by Clinical Endocrinology and the Klinefelter’s Syndrome Association UK
    1B
    Chair: H Jones (Barnsley)
    MTE3
    Endocrine and non-endocrine management of Klinefelter's Syndrome
    Richard Quinton (Newcastle, UK)
    08:00 - 08:45 
    Meet the Expert 4
    Supported by Clinical Endocrinology
    1C
    Chair: L Heisler (Cambridge)
    MTE4
    Optogenetics illuminates neuroendocrinology
    D Burdakov
    09:00 - 10:30 
    Symposium 6: Thyroid cell biology comes to your clinic
    Supported by Journal of Molecular Endocrinology
    1C
    Chairs: C Spitzweg (Munich, Germany) & V Smith (Birmingham)
    Emerging models of clinical relevance to thyroid disease
    09:00
    S6.1
    Development of functional thyroid tissue from embryonic stem cells
    Sabine Costagliola (Brussels, Belgium)
    09:30
    S6.2
    Factors involved in thyroid gland development and survival
    R Lauro
    10:00
    S6.3
    PBF signalling in thyroid tumourigenesis
    Chris McCabe (UK, Birmingham)
    09:00 - 10:30 
    Clinical Management Workshop 2: How do I do it?
    Supported by Endocrinology, Diabetes and Metabolism Case Reports CMW2.1 supported by Hypopara UK
    1A
    Chairs: J Ahlquist (Southend) & C Napier (Newcastle upon Tyne)
    09:00
    CMW2.1
    How do I localise parathyroid tumours?
    D Scott-Coombes
    09:15
    CMW2.2
    How and when do I initiate treatment for central hypothyroidism?
    L Persani (Milan, Italy)
    09:30
    CMW2.3
    How do I manage adrenal replacement in pregnancy?
    W Arlt
    09:45
    CMW2.4
    How do I investigate and manage sweating?
    F Swords
    10:00
    CMW2.5
    How and when do I treat the older male with a borderline testosterone?
    F Wu
    10:15
    CMW2.6
    How do I investigate and manage hyponatraemia?
    S Ball
    09:00 - 10:30 
    Oral Communications 3: Steroids
    3B
    Chairs: C Cummins (Toronto, Canada) & D Nanus (Birmingham)
    09:00
    OC3.1
    Lack of 11β-hydroxysteroid dehydrogenase type 1 ameliorates the adverse features of Cushing’s syndrome
    S Morgan
    09:15
    OC3.2
    5α-Reductase is a regulator of glucocorticoid action and metabolic phenotype in human liver
    M Nasiri
    09:30
    OC3.3
    The 21-hydroxylase pseudogene may have a role in induction of tolerance to steroidogenic machinery
    A Mitchell
    09:45
    OC3.4
    Pre-receptor glucocorticoid metabolism across human ageing: the impact of gender and menopausal status
    Z Hassan-Smith
    10:00
    OC3.5
    Linking GWAS to gene function - CYP17A1 in hypertension
    L Diver
    10:15
    OC3.6
    Targeting of lysyl oxidase by steroids to reduce peritoneal fibrosis and scarring
    C Harlow
    09:00 - 10:30 
    Symposium 7: Natriuretic peptides: so much more than salt and water
    1B
    Chairs: C McArdle (Bristol) & S Mirczuk (London)
    Novel functions for natriuretic peptides
    09:00
    S7.1
    Guanylyl cyclases in cardiomyopathy
    M Kuhn (Wuerzburg, Germany)
    09:30
    S7.2
    Natriuretic peptides in pituitary development and function
    R Fowkes
    10:00
    S7.3
    Natriuretic peptides in cardiovascular disease
    A Hobbs
    10:30 - 11:00 
    Tea & Coffee
    Hall 2A
    11:00 - 11:30 
    Plenary Lecture 1: Society for Endocrinology Dale Medal Lecture 2013
    1A
    Chair: A Grossman (Oxford)
    PL1
    Nuclear receptors, metabolism and the hunger games
    R Evans (La Jolla, USA)
    11:30 - 12:00 
    Plenary Lecture 2: Society for Endocrinology Dale Medal Lecture 2014
    1A
    Chair: A Grossman (Oxford)
    PL2
    Coactivators: Master Genes for Physiology and Pathology
    B O'Malley (Pittsburg, USA)
    12:00 - 14:00 
    Lunch & poster viewing
    Odd-numbered posters attended 12:00 - 13:00; Even-numbered posters attended 13:00 - 14:00
    Hall 2A
    12:45 - 13:45 
    Ipsen Industry Sponsored Satellite Symposia
    Optimising outcomes for patients with acromegaly and NETs
    3AB
    Chair: A Grossman (Oxford)
    High-dose lanreotide Autogel for treatment-naive patients with acromegaly: the results of the PRIMARYS trial
    J Bevan
    SAGIT – A disease staging tool to personalise patient management for acromegaly
    S Petersenn (Hamburg, Germany)
    New data confirming the beneficial role of lanreotide Autogel in the management of patients with a NET
    Aled Rees (Cardiff, United Kingdom)
    14:00 - 15:30 
    Oral Communications 4: Thyroid and Bone
    1C
    Chairs: K Boelaert (Birmingham) & F Hannan (Liverpool)
    14:00
    OC4.1
    Adaptor protein-2 sigma subunit mutations causing familial hypocalciuric hypercalcaemia type 3 exert dominant-negative effects
    S Howles
    14:15
    OC4.2
    PHOSPHO1: roles beyond skeletal mineralisation
    K Oldknow
    14:30
    OC4.3
    TRα mutation causes a severe and thyroxine-resistant skeletal dysplasia
    J Bassett
    14:45
    OC4.4
    Thyroid hormones stimulate osteoclastogenesis via TRα-dependent actions in osteoblasts
    J Logan
    15:00
    OC4.5
    A mutation in the 5’UTR of GNA11 causes familial hypocalciuric hypercalcemia type 2 (FHH2) due to reduced translational efficiency
    S Howles
    15:15
    OC4.6
    An ENU-induced Tyr265Stop mutation in Polg2 is associated with renal calcification in RCALC2 mice
    Caroline Gorvin (Birmingham, UK)
    14:00 - 15:30 
    Young Endocrinologists' Symposium: Establishing successful collaborations
    1B
    Chairs: A Lansdown (Cardiff) & G Begum (Manchester)
    Making the most of interdisciplinary collaborations and peer-to-peer networking
    14:00
    YE1.1
    What makes a successful collaboration between a basic scientist and a clinician?
    W Arlt
    14:15
    YE1.2
    How do I talk to a bioinformatician/mathematician/engineer?
    C McArdle
    14:30
    YE1.3
    Industrial collaborations - where to start?
    J Piner
    14:45
    YE1.4
    Biobanking – what is it, and how could they be beneficial to me?
    J Tobias
    15:00
    YE1.5
    Peer-to-peer collaborations: Importance of YE groups
    K Chapman
    15:15
    Panel discussion
    14:00 - 15:30 
    Symposium 8: Chronic disease and growth
    3B
    Chairs: F Ahmed (Glasgow) & L Dunford (Leicester)
    Chronic inflammation and growth hormone signalling
    14:00
    S8.1
    Understanding growth hormone action through the growth plate
    Colin Farquharson
    14:30
    S8.2
    Targeting SOCS Proteins to Combat Inflammation
    S Yarwood
    15:00
    S8.3
    Managing abnormalities of growth in chronic disease
    D Simon (Paris, France)
    14:00 - 15:30 
    Symposium 9: MEN1- from molecular pathology to therapies
    Supported by Endocrine-Related Cancer and the Association of Multiple Endocrine Neoplasia Disorders
    1A
    Chairs: J Newell-Price (Sheffield) & G Walls (Oxford)
    Current understanding and future perspectives in MEN1
    14:00
    S9.1
    Current understanding and future perspectives in MEN1
    S Agarwal (Bethesda, USA)
    14:30
    S9.2
    Genetics, pathophysiology and translational models of MEN1
    Raj Thakker (Oxford, United Kingdom)
    15:00
    S9.3
    Practical management of patients with MEN1
    B Skogseid (Uppsala, Sweden)
    15:30 - 16:00 
    Tea & Coffee
    Hall 2A
    16:00 - 16:45 
    Meet the Expert 3 (repeat)
    Supported by Clinical Endocrinology and the Klinefelter’s Syndrome Association UK
    3B
    Chair: H Jones (Barnsley)
    MTE3
    Endocrine and non-endocrine management of Klinefelter's Syndrome (repeat)
    Richard Quinton (Newcastle, UK)
    16:00 - 17:30 
    Oral Communications 5: Pituitary
    1B
    Chairs: J Davies (Manchester) & R Watkins (Birmingham)
    16:00
    OC5.1
    Increased frequency and earlier onset of pituitary tumours in mice deleted for a multiple endocrine neoplasia type 1 (MEN1) allele and null for prolyl hydroxylase domain protein 1 (PHD1) (Men1+/-/Phd1-/-)
    M Stevenson
    16:15
    OC5.2
    Implications of the upregulation of lysine specific demethylase (LSD) 1 in the pathogenesis of pituitary adenomas
    I Thompson
    16:30
    OC5.3
    The Wnt/β-catenin effector Tcf3/TCF7L1 is required for normal hypothalamic-pituitary development and mutation in this gene is associated with congenital hypopituitarism
    C Gaston-Massuet
    16:45
    OC5.4
    GnRH pulse frequency-dependent regulation of ICER, a modulator of FSHβ transcription, is attenuated by MEKI/II blockade
    I Thompson
    17:00
    OC5.5
    Spatio-temporal analysis of prolactin gene transcription dynamics reveals short range co-ordination of lactotroph transcription activity in pituitary tissue
    K Featherstone
    17:15
    OC5.6
    A GH antagonist fusion with GH binding protein is biologically active, shows delayed clearance and inhibits growth in a rabbit model
    I Wilkinson
    16:00 - 17:30 
    Symposium 10: Fat and bone
    Supported by Endocrine Connections and the Klinefelter’s Syndrome Association UK
    1A
    Chairs: P Dimitri (Sheffield) & R Crowley (Birmingham)
    Body composition and bone
    16:00
    S10.1
    Fat and its influence on bone
    J Walsh
    16:30
    S10.2
    Obesity and fractures - what is the inter-relationship?
    J Compston
    17:00
    S10.3
    Energy Deficiency, Amenorrhea and the Skeleton:  Challenges and Therapies
    16:45 - 17:30 
    Meet the Expert 5
    Supported by Clinical Endocrinology
    3B
    Chair: P Trainer (Manchester)
    MTE5
    Pituitary replacement therapy
    P Carroll
    17:40 - 18:10 
    Plenary Lecture 3: Clinical Endocrinology Trust Visiting Professor Lecture
    Supported by Clinical Endocrinology Trust
    1A
    Chair: J Connell (Dundee)
    PL3
    Adrenocortical tumours - from bench to bedside and back
    Bruno Allolio (Würzburg, Germany)
    19:30 -  
    Conference dinner and Awards Ceremony
    07:45 - 08:00 
    Breakfast
    08:00 - 08:45 
    Meet the Expert 5 (repeat)
    Supported by Clinical Endocrinology
    1A
    Chair: P Trainer (Manchester)
    MTE5
    Pituitary replacement therapy (repeat)
    P Carroll
    08:00 - 08:45 
    Meet the Expert 6
    Supported by Clinical Endocrinology
    3B
    Chair: C Brain (London)
    MTE6
    Delayed puberty
    J Blair
    08:00 - 08:45 
    Meet the Expert 7
    Supported by Clinical Endocrinology and the Thyroid Eye Disease Charitable Trust
    1B
    Chair: J Gilbert (London)
    MTE7
    Who should the endocrinologist ask the ophtalmologist to review?
    Daniel Ezra (London, UK)
    08:00 - 08:45 
    Society for Endocrinology Journal Awards
    1C
    Chair: D Ray (Manchester)
    08:00 - 08:09
    JA 1
    Society for Endocrinology Journal Award - Journal of Endocrinology: Mice deficient in PAPP-A show resistance to the development of diabetic nephropathy
    C Conover (Rochester, USA on behalf of the author group)
    08:09 - 08:18
    JA 2
    Society for Endocrinology Journal Award - Journal of Molecular Endocrinology:Thyroid-specific inactivation of KIF3A alters TSH signaling pathway and leads to hypothyroidism
    MC Many (Louvain-la-Neuve, Belgium on behalf of the author group)
    08:18 - 08:27
    JA 3
    Society for Endocrinology Journal Award - Endocrine-Related Cancer: Highly prevalent TERT promoter mutations in aggressive thyroid cancers
    M Xing (Baltimore, USA on behalf of the author group)
    08:27 - 08:36
    JA 4
    Society for Endocrinology Journal Award - Clinical Endocrinology: What predicts adverse outcomes in untreated primary hyperparathyroidism? The Parathyroid Epidemiology and Audit Research Study (PEARS)
    G Leese
    08:36 - 08:45
    JA 5
    Society for Endocrinology Journal Award - Endocrine Connections: PKA regulatory subunit R2B is required for murine and human adipocyte differentiation
    A Spada (Milan, Italy on behalf of the author group)
    08:45 - 09:25 
    Society for Endocrinology AGM
    1A
    09:30 - 11:00 
    Education Workshop 2: Practical publishing advice
    3B
    Chair: D Ray (Manchester)
    09:30
    EW2.1
    Introduction
    D Ray
    09:35
    EW2.2
    Publishing ethics: Fabrication, Falsification and Plagiarism
    A Clark
    09:45
    EW2.3
    The peer review process
    C Høybye (Stockholm, Sweden)
    09:55
    EW2.4
    Writing an attention grabbing abstract
    F Weber (Essen, Germany)
    10:05
    EW2.5
    Responding to reviewer comments
    S Ball
    10:15
    EW2.6
    The art of scientific writing
    Maralyn Druce (London, UK)
    10:25
    EW2.7
    Open Access
    L Flook
    10:35
    Questions and discussion
    09:30 - 11:00 
    Nurse Session 1 - Cushing's Syndrome
    1B
    Chairs: N Kieffer (Leicester) & J Andrew (Leeds)
    09:30
    N1.1
    Investigating and Diagnosing Cushing’s Syndrome -not as straightforward as it seems?
    K Meeran
    09:55
    N1.2
    The role of the Endocrine Nurse in the Management of patients with Cushing’s syndrome
    W Geilvoet (Rotterdam, The Netherlands)
    10:20
    N1.3
    Why do ‘cured’ Cushing’s patients need long-term follow up?
    S Webb (Barcelona, Spain)
    10:45
    N1.4
    Cushing’s patient experience
    A Patrick
    09:30 - 11:00 
    Symposium 11: Some like it hot - new insights into brown adipose tissue
    1C
    Chairs: S O'Rahilly (Cambridge) & S Virtue (Cambridge)
    Emerging biology of brown adipose tissue
    09:30
    S11.1
    Mechanisms of brown adipocyte determination
    P Seale (Philadelphia, USA)
    10:00
    S11.2
    The metabolic capacities of brown adipose tissue
    B Cannon (Stockholm, Sweden)
    10:30
    S11.3
    How brown is human brown adipose tissue?
    S Enerback (Gothenburg, Sweden)
    09:30 - 11:00 
    Clinical Management Workshop 3: Improving the care of young people in endocrinology
    Supported by Clinical Endocrinology
    1A
    Chairs: H Gleeson (Leicester) & R El-Khairi (London)
    09:30
    CMW3.1
    Adolescent health care in the UK in 2014
    B White
    10:00
    CMW3.2
    Adrenal replacement in adolescents and young adults
    P Hindmarsh (London, UK)
    10:30
    CMW3.3
    Optimising bone health in adolescents and young adults
    N Shaw (Birmingham, UK)
    11:00 - 11:30 
    Tea & Coffee
    Exhibtion Hall
    11:30 - 12:00 
    Plenary Lecture 4: Society for Endocrinology European Medal Lecture
    1A
    Chair: G Williams (London)
    PL4
    Mechanisms of thyroid hormone resistance
    T Visser (Rotterdam, Netherlands)
    12:00 - 12:30 
    Plenary Lecture 5: Society for Endocrinology Transatlantic Medal Lecture
    1A
    Chair: D Ray (Manchester)
    PL5
    Transcriptional Coordination of Circadian and Metabolic Physiology
    M Lazar (Philadelphia, USA)
    12:30 - 13:45 
    Lunch & poster viewing
    Shortlisted posters attended
    Hall 2A
    12:45 - 13:45 
    Viropharma Industry Sponsored Satellite Symposia
    New insights in the management of Adrenal Insufficiency in the UK
    3AB
    Chair: S Pearce (Newcastle-Upon-Tyne)
    12:45 - 12:55
    Introduction: The unmet medical need in adrenal insufficiency and the importance of circadian rhythm
    S Pearce (Newcastle, UK)
    12:55 - 13:10
    Adrenal Insufficiency today: the Salford project
    P Trainer
    13:10 - 13:25
    Adrenal Insufficiency today: a report from the EU-AIR registry
    Robert Murray (Leeds, UK)
    13:25 - 13:40
    Patient cases and physician experience
    R Pivonello (Naples, Italy)
    13:40 - 13:45
    Closing remarks
    S Pearce (Newcastle, UK)
    13:45 - 14:30 
    Meet the Expert 8
    1C
    Chair: C McCabe (Birmingham)
    MTE8
    Growing organs in the lab
    A Mel
    13:45 - 15:15 
    Nurses Session 2: The journey of endocrine nursing research: from evidence based practice to independent research
    1B
    Chairs: L Shephard (Birmingham) & V Fazal-Sanderson (Oxford)
    13:45
    N2.1
    Background on the journey of endocrine nursing research
    L Shepherd
    13:50
    N2.2
    How to audit and evaluate your own practice
    J Munday
    14:15
    N2.3
    The role of the endocrine nurse in clinical trials
    A Marland
    14:40
    N2.4
    Independent nursing research
    S Llahana
    15:05
    Questions and discussion
    13:45 - 15:15 
    Symposium 12: Getting excited about sugar - the brain and blood glucose control
    Supported by Endocrine Connections
    1A
    Chairs: R McCrimmon (Dundee) & B Challis (Cambridge)
    How the brain orchestrates glucose metabolism
    13:45
    S12.1
    How the brain senses blood glucose
    M Evans
    14:15
    S12.2
    Vagal control of energy metabolism
    S Trapp
    14:45
    S12.3
    Does glucagon need the brain for its effects on blood glucose?
    R McCrimmon
    13:45 - 15:15 
    Oral Communications 6: Clinical
    3B
    Chairs: R Semple (Cambridge) & A Puttanna (Walsall)
    13:45
    OC6.1
    Adverse outcome in glucocorticoid-induced adrenal suppression; an analysis of short synacthen tests in 2782 patients
    M Chapman
    14:00
    OC6.2
    Localising parathyroid adenomas. Which imaging modality is best? Pre-operative localisation studies in patients with primary hyperparathyroidism: a large audit in a London tertiary centre
    D Lewis
    14:15
    OC6.3
    Sirolimus therapy for a patient with segmental overgrowth due to a mosaic activating mutation in phosphatidylinositol-3-kinase (PI3K)
    V Parker
    14:30
    OC6.4
    Reduced cognitive performance and altered white matter microstructure in young insulin-resistant women with polycystic ovary syndrome
    M Udiawar
    14:45
    OC6.5
    Effectiveness of metyrapone in 195 patients with Cushing’s syndrome
    E Daniel
    15:00
    OC6.6
    11C-Methionine PET-CT co-registered with volume MRI: a novel adjunctive imaging modality to aid diagnosis and management in patients with pituitary adenomas
    O Koulouri
    14:30 - 15:15 
    Meet the Expert 9
    1C
    Chairs: H Turner (Oxford) & P Hadoke (Edinburgh)
    MTE9
    Novel techniques to assess angiogenesis
    S Germain (Paris, France)
    15:15 - 15:45 
    Tea & Coffee
    Hall 2A
    15:45 - 16:15 
    Oral Communication and Poster Prize Ceremony
    1A
    Chairs: A Grossman (Oxford) & C McCabe (Birmingham)
    16:15 - 16:45 
    Plenary Lecture 6: British Tyroid Association Pitt-Rivers Lecture
    Supported by Clinical Endocrinology Trust
    1A
    Chair: G Williams (London)
    PL6
    Disorders of thyroid hormone action: insights from human genetics
    Krishna Chatterjee (Cambridge, UK)
    16:45 - 17:15 
    Plenary Lecture 7: Society for Endocrinology Medal Lecture
    1A
    Chair: D Ray (Manchester)
    PL7
    The clock in the pituitary gland: timing annual cycles
    A Loudon
    07:45 - 08:00 
    Breakfast
    08:00 - 08:45 
    Meet the Expert 1 (repeat)
    Supported by Clinical Endocrinology
    1B
    Chair: J Newell-Price (Sheffield)
    MTE1
    Medical management of Cushing's syndrome (repeat)
    S Akker
    08:00 - 08:45 
    Meet the Expert 2 (repeat)
    Supported by Clinical Endocrinology
    1C
    Chair: N Gittoes (Birmingham)
    MTE2
    Vitamin D replacement: how much, how often and for whom? (repeat)
    P Selby
    08:45 - 09:15 
    Plenary Lecture 8: Clinical Endocrinology Trust Lecture
    Supported by the Clinical Endocrinology Trust
    1A
    Chair: JS Bevan (Aberdeen)
    PL8
    Understanding glucocorticoid action, and the role of the glucocorticoid receptor
    D Ray
    09:15 - 09:45 
    Plenary Lecture 9: Society for Endocrinology Hoffenberg International Medal Lecture
    1A
    Chair: C McCabe (Birmingham)
    PL9
    Male Fertility Regulation; achievements and frustrations
    R McLachlan (Clayton, Australia)
    09:45 - 10:15 
    Society for Endocrinology Emergency Endocrine Guidance
    1A
    Chair: J Franklyn (Birmingham)
    SFE1.1
    Acute Hypercalcaemia and Acute Hypocalcaemia