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Mon 24 Mar 2014
Mon 24
Tue 25 Mar 2014
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Wed 26 Mar 2014
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Thu 27 Mar 2014
Thu 27
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Monday 24 March
20 sessions
09:00 -
Registration
11:00 - 12:30
Symposium 1: GnRH biology - from pulses to longevity
Supported by Journal of Molecular Endocrinology
1B
Chairs: H Christian (Oxford) & R Perrett (Bristol)
From novel insights into GnRH timing and central control of reproduction to new discoveries in hypothalamic inflammatory change and ageing
11:30
S1.2
Biological insights from genetically tagged gonadotropes
U Boehm
12:00
S1.3
GnRH and inflammatory signalling in the ageing hypothalamus
D Cai
(Bronx, USA)
11:00 - 12:30
Symposium 2: The upside of glucocorticoids in metabolism
Supported by Journal of Endocrinology
1C
Chairs: R Stimson (Edinburgh) & S Morgan (Birmingham)
Amending our thinking of the way GCs work
11:00
S2.1
Insulin sensitisation of adipose tissue by glucocorticoids
J Tomlinson
11:30
S2.2
Maintaining the anti-inflammatory action of glucocorticoid without the metabolic side effects
C Cummins
(Toronto, Canada)
12:00
S2.3
Glucocorticoids and protection from pancreatic beta cell failure
N Morton
11:00 - 12:30
Symposium 3: Emerging Clinical importance of iodine
Supported by Endocrine-Related Cancer and the British Thyroid Foundation
3B
Chairs: M Vanderpump (London) & J Waung (London)
New clinical applications in iodine biology
11:00
S3.1
Iodine nutrition and neurodevelopment
M Rayman
11:30
S3.2
Regulation of NIS function in thyroid and breast cancer
G Brent
(Los Angeles, USA)
12:00
S3.3
Use of radioiodine in the imaging and therapy of non-thyroidal tumours
C Spitzweg
(Munich, Germany)
11:00 - 12:30
Clinical Management Workshop 2: How do I do it?
Supported by Endocrinology, Diabetes and Metabolism Case Reports CMW2.1 supported by Hypopara UK
1A
Chairs: J Ahlquist (Southend) & C Napier (Newcastle upon Tyne)
11:00
CMW2.1
How do I localise parathyroid tumours?
D Scott-Coombes
11:15
CMW2.2
How and when do I initiate treatment for central hypothyroidism?
L Persani
(Milan, Italy)
11:30
CMW2.3
How do I manage adrenal replacement in pregnancy?
W Arlt
11:45
CMW2.6
How do I investigate and manage hyponatraemia?
S Ball
12:00
CMW2.5
How and when do I treat the older male with a borderline testosterone?
F Wu
12:15
CMW2.4
How do I investigate and manage sweating?
F Swords
12:30 - 13:45
Lunch
Hall 2A
12:45 - 13:45
Internis Industry Sponsored Satellite Symposia
Vitamin D – the Dark Truth
1C
Chair: A Grosso (London)
12:45 - 13:05
Clinical Update on Vitamin D
S Davies
13:05 - 13:25
Shedding light on the Health Economics of Vitamin D
C Poole
13:25 - 13:45
The Dark Truth of Prescribing Unlicensed Vitamin D
P Feldschreiber
12:45 - 13:45
HRA Pharma Industry Sponsored Satellite Symposia
Cushing’s syndrome and adrenocortical carcinoma management: are we making progress?
1B
Chair: R Feelders (Rotterdam, Netherlands)
12:45 - 12:50
Welcome and introduction
R Feelders
(Rotterdam, Netherlands)
12:50 - 13:00
Current challenges in the management of Cushing’s syndrome
A Grossman
13:00 - 13:20
Use of Steroidogenesis inhibitors for Cushing’s syndrome. Audit of 13 UK tertiary centres
John Newell-Price
(Sheffield, UK)
13:20 - 13:35
Multimodal therapy in the management of advanced ACC
S Aylwin
13:35 - 13:45
Questions and Answers
13:45 - 15:15
Applied Physiology Workshop: A guide to the analysis of energy metabolism
Supported by Journal of Endocrinology
1B
Chairs: G Lavery (Birmingham) & D Macfarlane (Dundee)
How to assess and quantitate energy usage and interpret the data
13:45
APW1.1
Assessing energy demand in living organisms
J Nedergaard
(Stockholm, Sweden)
14:15
APW1.2
Lipid metabolism: from mice to men?
S Virtue
14:45
APW1.3
Tracking lipid energy partitioning in human liver
L Hodson
13:45 - 15:15
Oral Communications 1: Young Endocrinologists' Prize Session
1A
Chairs: C McCabe (Birmingham) & S Mirczuk (London)
13:45
OC1.1
The Thr92Ala substitution in deiodonase-2 is associated with increased odds of a sub-optimal IQ score in children with low-normal thyroid function
P Taylor
14:00
OC1.2
Characterisation of adrenocortical progenitor cells: isolation of mesenchymal stem cell-like cell populations from human adrenal cortex
E Gan
14:15
OC1.3
Angiogenic factors sFlt1 and PlGF are novel determinants of newborn thyroid (dys)function: the Generation R study
T Korevaar
14:30
OC1.4
Single molecule analysis of GPCR transactivation reveals oligomeric complexes that regulate signal sensitivity
Kim Jonas
(London, UK)
14:45
OC1.5
Kisspeptin - a novel physiological trigger for oocyte maturation in IVF treatment
A Abbara
15:00
OC1.6
A loss-of-function mutation in the prolactin receptor (PRLR) causes familial hyperprolactinaemia
Caroline Gorvin
(Birmingham, UK)
13:45 - 15:15
Symposium 4: Putting flesh on the bones
3B
Chairs: N Shaw (Birmingham) & S Howles (Oxford)
Genetic disorders of bone and mineral metabolism
13:45
S4.1
Assessment of abnormalities of skeletal development
E Kinning
14:15
S4.2
Osteogenesis imperfecta - management beyond childhood
N Gittoes
14:45
S4.3
Management of hypophosphatemic rickets
T Carpenter
(New Haven, USA)
15:15 - 15:45
Tea & Coffee
Hall 2A
15:45 - 17:15
Education Workshop 1: Teaching and learning in Endocrinology
3B
Chairs: A Crown (Brighton) & H Christian (Oxford)
15:45
EW1.1
Endocrinologists as teachers: integrating teaching and practice in the real world
K Meeran
16:05
EW1.2
Using technology to enhance your teaching in endocrinology
S Ball
16:25
EW1.3
Exams, and the future of assessment in medicine. A view from the MRCP(UK)
J Dacre
16:45
EW1.4
Interprofessional learning through and for multidisciplinary working
D Freeth
17:05
Questions and discussion
15:45 - 17:15
Clinical Management Workshop 1: Management of complex obesity
Supported by Clinical Endocrinology
1A
Chairs: B McGowan (London) & K McCullough (London)
15:45
CMW1.1
Have the new commissioning guidelines for bariatric surgery improved patient's pathways?
J Barth
16:15
CMW1.2
Medical management of severe obesity
J Wilding
16:45
CMW1.3
Endocrine and metabolic complications post-bariatric surgery
Nick Finer
(London, United Kingdom)
15:45 - 17:15
Oral Communications 2: Endocrine regulation of cell behaviour
1B
Chairs: G Lavery (Birmingham) & G WIllis (Cardiff)
15:45
OC2.1
A novel modulator of cell invasion and metastasis
R Watkins
16:00
OC2.2
Inhibition of human NET cell proliferation by a peptide identified through phage display screening
M Stevenson
16:15
OC2.3
A20 confers protection against TRAIL-induced apoptosis in the pancreatic beta-cell
R Yates
16:30
OC2.4
Influence of glucocorticoid receptor density on development and remodelling of the heart
R Richardson
16:45
OC2.5
Beta-cells require CFTR for glucose-induced insulin secretion
J Robinson
17:00
OC2.6
A potential role for food-derived microRNAs in human placental development
K Timms
15:45 - 17:15
Symposium 5: Endocrine consequences of major trauma
1C
Chairs: A Logan (Birmingham) & M Sherlock (Dublin, Ireland)
Pathophysiological changes associated with injury
15:45
S5.1
Endocrine mechanisms of sarcopenia
J Lord
16:15
S5.2
Pituitary sequelae of traumatic brain injury
C Thompson
(Dublin, Ireland)
16:45
S5.3
Thyroid hormone economy in critical illness
A Boelen
(Amsterdam, The Netherlands)
17:25 - 18:25
SfE Young Endocrinologists' Prize Lectures
1A
Chairs: J Franklyn (Birmingham) & K Chapman (Edinburgh)
YEP1.1
Basic Prize Lecture: Sox2+ cells of the postnatal pituitary can differentiate into hormone producing cells in vivo and have tumour-inducing potential
C Andoniadou
YEP1.2
Clinical Prize Lecture: Clinical effects of kisspeptin on reproductive hormone secretion, LH pulsatility and oocyte maturation during IVF treatment
C Jayasena
18:25 - 19:15
Debate: This house believes Genome Wide Association Studies will have no impact upon clinical endocrinology
1A
Chair: B Walker (Edinburgh)
For:
S O'Rahilly
Against:
M Caulfield
19:15 - 21:00
Welcome Reception
Hall 2A
20:15 - 22:00
Young Endocrinologists' Social Evening and Quiz
3AB
Tuesday 25 March
61 sessions
07:45 - 08:00
Breakfast
07:45 -
Registration
08:00 - 08:45
Meet the Expert 1
Supported by Clinical Endocrinology
3B
Chair: J Newell-Price (Sheffield)
MTE1
Medical management of Cushing's syndrome
S Akker
08:00 - 08:45
Meet the Expert 2
Supported by Clinical Endocrinology
1A
Chair: N Gittoes (Birmingham)
MTE2
Vitamin D replacement: how much, how often and for whom?
P Selby
08:00 - 08:45
Meet the Expert 3
Supported by Clinical Endocrinology and the Klinefelter’s Syndrome Association UK
1B
Chair: H Jones (Barnsley)
MTE3
Endocrine and non-endocrine management of Klinefelter's Syndrome
Richard Quinton
(Newcastle, UK)
08:00 - 08:45
Meet the Expert 4
Supported by Clinical Endocrinology
1C
Chair: L Heisler (Cambridge)
MTE4
Optogenetics illuminates neuroendocrinology
D Burdakov
09:00 - 10:30
Symposium 6: Thyroid cell biology comes to your clinic
Supported by Journal of Molecular Endocrinology
1C
Chairs: C Spitzweg (Munich, Germany) & V Smith (Birmingham)
Emerging models of clinical relevance to thyroid disease
09:00
S6.1
Development of functional thyroid tissue from embryonic stem cells
Sabine Costagliola
(Brussels, Belgium)
09:30
S6.2
Factors involved in thyroid gland development and survival
R Lauro
10:00
S6.3
PBF signalling in thyroid tumourigenesis
Chris McCabe
(UK, Birmingham)
09:00 - 10:30
Clinical Management Workshop 2: How do I do it?
Supported by Endocrinology, Diabetes and Metabolism Case Reports CMW2.1 supported by Hypopara UK
1A
Chairs: J Ahlquist (Southend) & C Napier (Newcastle upon Tyne)
09:00
CMW2.1
How do I localise parathyroid tumours?
D Scott-Coombes
09:15
CMW2.2
How and when do I initiate treatment for central hypothyroidism?
L Persani
(Milan, Italy)
09:30
CMW2.3
How do I manage adrenal replacement in pregnancy?
W Arlt
09:45
CMW2.4
How do I investigate and manage sweating?
F Swords
10:00
CMW2.5
How and when do I treat the older male with a borderline testosterone?
F Wu
10:15
CMW2.6
How do I investigate and manage hyponatraemia?
S Ball
09:00 - 10:30
Oral Communications 3: Steroids
3B
Chairs: C Cummins (Toronto, Canada) & D Nanus (Birmingham)
09:00
OC3.1
Lack of 11β-hydroxysteroid dehydrogenase type 1 ameliorates the adverse features of Cushing’s syndrome
S Morgan
09:15
OC3.2
5α-Reductase is a regulator of glucocorticoid action and metabolic phenotype in human liver
M Nasiri
09:30
OC3.3
The 21-hydroxylase pseudogene may have a role in induction of tolerance to steroidogenic machinery
A Mitchell
09:45
OC3.4
Pre-receptor glucocorticoid metabolism across human ageing: the impact of gender and menopausal status
Z Hassan-Smith
10:00
OC3.5
Linking GWAS to gene function - CYP17A1 in hypertension
L Diver
10:15
OC3.6
Targeting of lysyl oxidase by steroids to reduce peritoneal fibrosis and scarring
C Harlow
09:00 - 10:30
Symposium 7: Natriuretic peptides: so much more than salt and water
1B
Chairs: C McArdle (Bristol) & S Mirczuk (London)
Novel functions for natriuretic peptides
09:00
S7.1
Guanylyl cyclases in cardiomyopathy
M Kuhn
(Wuerzburg, Germany)
09:30
S7.2
Natriuretic peptides in pituitary development and function
R Fowkes
10:00
S7.3
Natriuretic peptides in cardiovascular disease
A Hobbs
10:30 - 11:00
Tea & Coffee
Hall 2A
11:00 - 11:30
Plenary Lecture 1: Society for Endocrinology Dale Medal Lecture 2013
1A
Chair: A Grossman (Oxford)
PL1
Nuclear receptors, metabolism and the hunger games
R Evans
(La Jolla, USA)
11:30 - 12:00
Plenary Lecture 2: Society for Endocrinology Dale Medal Lecture 2014
1A
Chair: A Grossman (Oxford)
PL2
Coactivators: Master Genes for Physiology and Pathology
B O'Malley
(Pittsburg, USA)
12:00 - 14:00
Lunch & poster viewing
Odd-numbered posters attended 12:00 - 13:00; Even-numbered posters attended 13:00 - 14:00
Hall 2A
12:45 - 13:45
Ipsen Industry Sponsored Satellite Symposia
Optimising outcomes for patients with acromegaly and NETs
3AB
Chair: A Grossman (Oxford)
High-dose lanreotide Autogel for treatment-naive patients with acromegaly: the results of the PRIMARYS trial
J Bevan
SAGIT – A disease staging tool to personalise patient management for acromegaly
S Petersenn
(Hamburg, Germany)
New data confirming the beneficial role of lanreotide Autogel in the management of patients with a NET
Aled Rees
(Cardiff, United Kingdom)
14:00 - 15:30
Oral Communications 4: Thyroid and Bone
1C
Chairs: K Boelaert (Birmingham) & F Hannan (Liverpool)
14:00
OC4.1
Adaptor protein-2 sigma subunit mutations causing familial hypocalciuric hypercalcaemia type 3 exert dominant-negative effects
S Howles
14:15
OC4.2
PHOSPHO1: roles beyond skeletal mineralisation
K Oldknow
14:30
OC4.3
TRα mutation causes a severe and thyroxine-resistant skeletal dysplasia
J Bassett
14:45
OC4.4
Thyroid hormones stimulate osteoclastogenesis via TRα-dependent actions in osteoblasts
J Logan
15:00
OC4.5
A mutation in the 5’UTR of GNA11 causes familial hypocalciuric hypercalcemia type 2 (FHH2) due to reduced translational efficiency
S Howles
15:15
OC4.6
An ENU-induced Tyr265Stop mutation in Polg2 is associated with renal calcification in RCALC2 mice
Caroline Gorvin
(Birmingham, UK)
14:00 - 15:30
Young Endocrinologists' Symposium: Establishing successful collaborations
1B
Chairs: A Lansdown (Cardiff) & G Begum (Manchester)
Making the most of interdisciplinary collaborations and peer-to-peer networking
14:00
YE1.1
What makes a successful collaboration between a basic scientist and a clinician?
W Arlt
14:15
YE1.2
How do I talk to a bioinformatician/mathematician/engineer?
C McArdle
14:30
YE1.3
Industrial collaborations - where to start?
J Piner
14:45
YE1.4
Biobanking – what is it, and how could they be beneficial to me?
J Tobias
15:00
YE1.5
Peer-to-peer collaborations: Importance of YE groups
K Chapman
15:15
Panel discussion
14:00 - 15:30
Symposium 8: Chronic disease and growth
3B
Chairs: F Ahmed (Glasgow) & L Dunford (Leicester)
Chronic inflammation and growth hormone signalling
14:00
S8.1
Understanding growth hormone action through the growth plate
Colin Farquharson
14:30
S8.2
Targeting SOCS Proteins to Combat Inflammation
S Yarwood
15:00
S8.3
Managing abnormalities of growth in chronic disease
D Simon
(Paris, France)
14:00 - 15:30
Symposium 9: MEN1- from molecular pathology to therapies
Supported by Endocrine-Related Cancer and the Association of Multiple Endocrine Neoplasia Disorders
1A
Chairs: J Newell-Price (Sheffield) & G Walls (Oxford)
Current understanding and future perspectives in MEN1
14:00
S9.1
Current understanding and future perspectives in MEN1
S Agarwal
(Bethesda, USA)
14:30
S9.2
Genetics, pathophysiology and translational models of MEN1
Raj Thakker
(Oxford, United Kingdom)
15:00
S9.3
Practical management of patients with MEN1
B Skogseid
(Uppsala, Sweden)
15:30 - 16:00
Tea & Coffee
Hall 2A
16:00 - 16:45
Meet the Expert 3 (repeat)
Supported by Clinical Endocrinology and the Klinefelter’s Syndrome Association UK
3B
Chair: H Jones (Barnsley)
MTE3
Endocrine and non-endocrine management of Klinefelter's Syndrome (repeat)
Richard Quinton
(Newcastle, UK)
16:00 - 17:30
Oral Communications 5: Pituitary
1B
Chairs: J Davies (Manchester) & R Watkins (Birmingham)
16:00
OC5.1
Increased frequency and earlier onset of pituitary tumours in mice deleted for a multiple endocrine neoplasia type 1 (MEN1) allele and null for prolyl hydroxylase domain protein 1 (PHD1) (Men1+/-/Phd1-/-)
M Stevenson
16:15
OC5.2
Implications of the upregulation of lysine specific demethylase (LSD) 1 in the pathogenesis of pituitary adenomas
I Thompson
16:30
OC5.3
The Wnt/β-catenin effector Tcf3/TCF7L1 is required for normal hypothalamic-pituitary development and mutation in this gene is associated with congenital hypopituitarism
C Gaston-Massuet
16:45
OC5.4
GnRH pulse frequency-dependent regulation of ICER, a modulator of FSHβ transcription, is attenuated by MEKI/II blockade
I Thompson
17:00
OC5.5
Spatio-temporal analysis of prolactin gene transcription dynamics reveals short range co-ordination of lactotroph transcription activity in pituitary tissue
K Featherstone
17:15
OC5.6
A GH antagonist fusion with GH binding protein is biologically active, shows delayed clearance and inhibits growth in a rabbit model
I Wilkinson
16:00 - 17:30
Symposium 10: Fat and bone
Supported by Endocrine Connections and the Klinefelter’s Syndrome Association UK
1A
Chairs: P Dimitri (Sheffield) & R Crowley (Birmingham)
Body composition and bone
16:00
S10.1
Fat and its influence on bone
J Walsh
16:30
S10.2
Obesity and fractures - what is the inter-relationship?
J Compston
17:00
S10.3
Energy Deficiency, Amenorrhea and the Skeleton: Challenges and Therapies
16:45 - 17:30
Meet the Expert 5
Supported by Clinical Endocrinology
3B
Chair: P Trainer (Manchester)
MTE5
Pituitary replacement therapy
P Carroll
17:40 - 18:10
Plenary Lecture 3: Clinical Endocrinology Trust Visiting Professor Lecture
Supported by Clinical Endocrinology Trust
1A
Chair: J Connell (Dundee)
PL3
Adrenocortical tumours - from bench to bedside and back
Bruno Allolio
(Würzburg, Germany)
19:30 -
Conference dinner and Awards Ceremony
07:45 - 08:00
Breakfast
08:00 - 08:45
Meet the Expert 5 (repeat)
Supported by Clinical Endocrinology
1A
Chair: P Trainer (Manchester)
MTE5
Pituitary replacement therapy (repeat)
P Carroll
08:00 - 08:45
Meet the Expert 6
Supported by Clinical Endocrinology
3B
Chair: C Brain (London)
MTE6
Delayed puberty
J Blair
08:00 - 08:45
Meet the Expert 7
Supported by Clinical Endocrinology and the Thyroid Eye Disease Charitable Trust
1B
Chair: J Gilbert (London)
MTE7
Who should the endocrinologist ask the ophtalmologist to review?
Daniel Ezra
(London, UK)
08:00 - 08:45
Society for Endocrinology Journal Awards
1C
Chair: D Ray (Manchester)
08:00 - 08:09
JA 1
Society for Endocrinology Journal Award - Journal of Endocrinology: Mice deficient in PAPP-A show resistance to the development of diabetic nephropathy
C Conover
(Rochester, USA on behalf of the author group)
08:09 - 08:18
JA 2
Society for Endocrinology Journal Award - Journal of Molecular Endocrinology:Thyroid-specific inactivation of KIF3A alters TSH signaling pathway and leads to hypothyroidism
MC Many
(Louvain-la-Neuve, Belgium on behalf of the author group)
08:18 - 08:27
JA 3
Society for Endocrinology Journal Award - Endocrine-Related Cancer: Highly prevalent TERT promoter mutations in aggressive thyroid cancers
M Xing
(Baltimore, USA on behalf of the author group)
08:27 - 08:36
JA 4
Society for Endocrinology Journal Award - Clinical Endocrinology: What predicts adverse outcomes in untreated primary hyperparathyroidism? The Parathyroid Epidemiology and Audit Research Study (PEARS)
G Leese
08:36 - 08:45
JA 5
Society for Endocrinology Journal Award - Endocrine Connections: PKA regulatory subunit R2B is required for murine and human adipocyte differentiation
A Spada
(Milan, Italy on behalf of the author group)
08:45 - 09:25
Society for Endocrinology AGM
1A
09:30 - 11:00
Education Workshop 2: Practical publishing advice
3B
Chair: D Ray (Manchester)
09:30
EW2.1
Introduction
D Ray
09:35
EW2.2
Publishing ethics: Fabrication, Falsification and Plagiarism
A Clark
09:45
EW2.3
The peer review process
C Høybye
(Stockholm, Sweden)
09:55
EW2.4
Writing an attention grabbing abstract
F Weber
(Essen, Germany)
10:05
EW2.5
Responding to reviewer comments
S Ball
10:15
EW2.6
The art of scientific writing
Maralyn Druce
(London, UK)
10:25
EW2.7
Open Access
L Flook
10:35
Questions and discussion
09:30 - 11:00
Nurse Session 1 - Cushing's Syndrome
1B
Chairs: N Kieffer (Leicester) & J Andrew (Leeds)
09:30
N1.1
Investigating and Diagnosing Cushing’s Syndrome -not as straightforward as it seems?
K Meeran
09:55
N1.2
The role of the Endocrine Nurse in the Management of patients with Cushing’s syndrome
W Geilvoet
(Rotterdam, The Netherlands)
10:20
N1.3
Why do ‘cured’ Cushing’s patients need long-term follow up?
S Webb
(Barcelona, Spain)
10:45
N1.4
Cushing’s patient experience
A Patrick
09:30 - 11:00
Symposium 11: Some like it hot - new insights into brown adipose tissue
1C
Chairs: S O'Rahilly (Cambridge) & S Virtue (Cambridge)
Emerging biology of brown adipose tissue
09:30
S11.1
Mechanisms of brown adipocyte determination
P Seale
(Philadelphia, USA)
10:00
S11.2
The metabolic capacities of brown adipose tissue
B Cannon
(Stockholm, Sweden)
10:30
S11.3
How brown is human brown adipose tissue?
S Enerback
(Gothenburg, Sweden)
09:30 - 11:00
Clinical Management Workshop 3: Improving the care of young people in endocrinology
Supported by Clinical Endocrinology
1A
Chairs: H Gleeson (Leicester) & R El-Khairi (London)
09:30
CMW3.1
Adolescent health care in the UK in 2014
B White
10:00
CMW3.2
Adrenal replacement in adolescents and young adults
P Hindmarsh
(London, UK)
10:30
CMW3.3
Optimising bone health in adolescents and young adults
N Shaw
(Birmingham, UK)
11:00 - 11:30
Tea & Coffee
Exhibtion Hall
11:30 - 12:00
Plenary Lecture 4: Society for Endocrinology European Medal Lecture
1A
Chair: G Williams (London)
PL4
Mechanisms of thyroid hormone resistance
T Visser
(Rotterdam, Netherlands)
12:00 - 12:30
Plenary Lecture 5: Society for Endocrinology Transatlantic Medal Lecture
1A
Chair: D Ray (Manchester)
PL5
Transcriptional Coordination of Circadian and Metabolic Physiology
M Lazar
(Philadelphia, USA)
12:30 - 13:45
Lunch & poster viewing
Shortlisted posters attended
Hall 2A
12:45 - 13:45
Viropharma Industry Sponsored Satellite Symposia
New insights in the management of Adrenal Insufficiency in the UK
3AB
Chair: S Pearce (Newcastle-Upon-Tyne)
12:45 - 12:55
Introduction: The unmet medical need in adrenal insufficiency and the importance of circadian rhythm
S Pearce
(Newcastle, UK)
12:55 - 13:10
Adrenal Insufficiency today: the Salford project
P Trainer
13:10 - 13:25
Adrenal Insufficiency today: a report from the EU-AIR registry
Robert Murray
(Leeds, UK)
13:25 - 13:40
Patient cases and physician experience
R Pivonello
(Naples, Italy)
13:40 - 13:45
Closing remarks
S Pearce
(Newcastle, UK)
13:45 - 14:30
Meet the Expert 8
1C
Chair: C McCabe (Birmingham)
MTE8
Growing organs in the lab
A Mel
13:45 - 15:15
Nurses Session 2: The journey of endocrine nursing research: from evidence based practice to independent research
1B
Chairs: L Shephard (Birmingham) & V Fazal-Sanderson (Oxford)
13:45
N2.1
Background on the journey of endocrine nursing research
L Shepherd
13:50
N2.2
How to audit and evaluate your own practice
J Munday
14:15
N2.3
The role of the endocrine nurse in clinical trials
A Marland
14:40
N2.4
Independent nursing research
S Llahana
15:05
Questions and discussion
13:45 - 15:15
Symposium 12: Getting excited about sugar - the brain and blood glucose control
Supported by Endocrine Connections
1A
Chairs: R McCrimmon (Dundee) & B Challis (Cambridge)
How the brain orchestrates glucose metabolism
13:45
S12.1
How the brain senses blood glucose
M Evans
14:15
S12.2
Vagal control of energy metabolism
S Trapp
14:45
S12.3
Does glucagon need the brain for its effects on blood glucose?
R McCrimmon
13:45 - 15:15
Oral Communications 6: Clinical
3B
Chairs: R Semple (Cambridge) & A Puttanna (Walsall)
13:45
OC6.1
Adverse outcome in glucocorticoid-induced adrenal suppression; an analysis of short synacthen tests in 2782 patients
M Chapman
14:00
OC6.2
Localising parathyroid adenomas. Which imaging modality is best? Pre-operative localisation studies in patients with primary hyperparathyroidism: a large audit in a London tertiary centre
D Lewis
14:15
OC6.3
Sirolimus therapy for a patient with segmental overgrowth due to a mosaic activating mutation in phosphatidylinositol-3-kinase (PI3K)
V Parker
14:30
OC6.4
Reduced cognitive performance and altered white matter microstructure in young insulin-resistant women with polycystic ovary syndrome
M Udiawar
14:45
OC6.5
Effectiveness of metyrapone in 195 patients with Cushing’s syndrome
E Daniel
15:00
OC6.6
11C-Methionine PET-CT co-registered with volume MRI: a novel adjunctive imaging modality to aid diagnosis and management in patients with pituitary adenomas
O Koulouri
14:30 - 15:15
Meet the Expert 9
1C
Chairs: H Turner (Oxford) & P Hadoke (Edinburgh)
MTE9
Novel techniques to assess angiogenesis
S Germain
(Paris, France)
15:15 - 15:45
Tea & Coffee
Hall 2A
15:45 - 16:15
Oral Communication and Poster Prize Ceremony
1A
Chairs: A Grossman (Oxford) & C McCabe (Birmingham)
16:15 - 16:45
Plenary Lecture 6: British Tyroid Association Pitt-Rivers Lecture
Supported by Clinical Endocrinology Trust
1A
Chair: G Williams (London)
PL6
Disorders of thyroid hormone action: insights from human genetics
Krishna Chatterjee
(Cambridge, UK)
16:45 - 17:15
Plenary Lecture 7: Society for Endocrinology Medal Lecture
1A
Chair: D Ray (Manchester)
PL7
The clock in the pituitary gland: timing annual cycles
A Loudon
07:45 - 08:00
Breakfast
08:00 - 08:45
Meet the Expert 1 (repeat)
Supported by Clinical Endocrinology
1B
Chair: J Newell-Price (Sheffield)
MTE1
Medical management of Cushing's syndrome (repeat)
S Akker
08:00 - 08:45
Meet the Expert 2 (repeat)
Supported by Clinical Endocrinology
1C
Chair: N Gittoes (Birmingham)
MTE2
Vitamin D replacement: how much, how often and for whom? (repeat)
P Selby
08:45 - 09:15
Plenary Lecture 8: Clinical Endocrinology Trust Lecture
Supported by the Clinical Endocrinology Trust
1A
Chair: JS Bevan (Aberdeen)
PL8
Understanding glucocorticoid action, and the role of the glucocorticoid receptor
D Ray
09:15 - 09:45
Plenary Lecture 9: Society for Endocrinology Hoffenberg International Medal Lecture
1A
Chair: C McCabe (Birmingham)
PL9
Male Fertility Regulation; achievements and frustrations
R McLachlan
(Clayton, Australia)
09:45 - 10:15
Society for Endocrinology Emergency Endocrine Guidance
1A
Chair: J Franklyn (Birmingham)
SFE1.1
Acute Hypercalcaemia and Acute Hypocalcaemia
James Turner
(UK)
SFE1.2
Pituitary Apoplexy
S Baldeweg
10:15 - 10:45
Tea & Coffee
3AB
10:45 - 11:30
Meet the Expert 6 (repeat)
1B
Chair: C Brain (London)
MTE6
Delayed puberty (repeat)
J Blair
10:45 - 12:15
Clinical Management Workshop 4: Cardiovascular risk in endocrine disease
Supported by Endocrinology, Diabetes & Metabolism Case Reports and the Turner Syndrome Support Society
1A
Chairs: A Bates (Stourbridge) & J Thomas (Taunton)
10:45
CMW4.1
Cardiovascular risk in Turner's syndrome
M Donaldson
11:15
CMW4.2
Valvular disease in prolactinomas- weighing up the evidence
William Drake
(London, UK)
11:45
CMW4.3
Cardiovascular risk in childhood cancer survivors
E Crowne
10:45 - 12:45
Senior Endocrinologists' Session
1C
Chairs: B Cooke (Harpenden) & P Belchetz (Wetherby)
10:45
SE1.4
The Foundling Hospital
B Cooke
11:09
SE1.2
1776 Revolution in Liverpool. Matthew Dobson discovers Hyperglycaemia!
I MacFarlane
11:33
SE1.3
Macroprolacin - To seek or ignore : a Trans-Atlantic Divide
J McKenna
(Dublin, Ireland)
11:57
SE1.1
How important is luck for major discoveries?
J Tata
12:21
SE1.5
Steroid Merchants of Edinburgh
I Mason
11:30 - 12:15
Meet the Expert 7 (repeat)
Supported by Clinical Endocrinology and the Thyroid Eye Disease Charitable Trust
1B
Chair: J Gilbert (London)
MTE7
Whom should the endocrinologist ask the ophtalmologist to review? (repeat)
Daniel Ezra
(London, UK)
Wednesday 26 March
61 sessions
07:45 - 08:00
Breakfast
07:45 -
Registration
08:00 - 08:45
Meet the Expert 1
Supported by Clinical Endocrinology
3B
Chair: J Newell-Price (Sheffield)
MTE1
Medical management of Cushing's syndrome
S Akker
08:00 - 08:45
Meet the Expert 2
Supported by Clinical Endocrinology
1A
Chair: N Gittoes (Birmingham)
MTE2
Vitamin D replacement: how much, how often and for whom?
P Selby
08:00 - 08:45
Meet the Expert 3
Supported by Clinical Endocrinology and the Klinefelter’s Syndrome Association UK
1B
Chair: H Jones (Barnsley)
MTE3
Endocrine and non-endocrine management of Klinefelter's Syndrome
Richard Quinton
(Newcastle, UK)
08:00 - 08:45
Meet the Expert 4
Supported by Clinical Endocrinology
1C
Chair: L Heisler (Cambridge)
MTE4
Optogenetics illuminates neuroendocrinology
D Burdakov
09:00 - 10:30
Symposium 6: Thyroid cell biology comes to your clinic
Supported by Journal of Molecular Endocrinology
1C
Chairs: C Spitzweg (Munich, Germany) & V Smith (Birmingham)
Emerging models of clinical relevance to thyroid disease
09:00
S6.1
Development of functional thyroid tissue from embryonic stem cells
Sabine Costagliola
(Brussels, Belgium)
09:30
S6.2
Factors involved in thyroid gland development and survival
R Lauro
10:00
S6.3
PBF signalling in thyroid tumourigenesis
Chris McCabe
(UK, Birmingham)
09:00 - 10:30
Clinical Management Workshop 2: How do I do it?
Supported by Endocrinology, Diabetes and Metabolism Case Reports CMW2.1 supported by Hypopara UK
1A
Chairs: J Ahlquist (Southend) & C Napier (Newcastle upon Tyne)
09:00
CMW2.1
How do I localise parathyroid tumours?
D Scott-Coombes
09:15
CMW2.2
How and when do I initiate treatment for central hypothyroidism?
L Persani
(Milan, Italy)
09:30
CMW2.3
How do I manage adrenal replacement in pregnancy?
W Arlt
09:45
CMW2.4
How do I investigate and manage sweating?
F Swords
10:00
CMW2.5
How and when do I treat the older male with a borderline testosterone?
F Wu
10:15
CMW2.6
How do I investigate and manage hyponatraemia?
S Ball
09:00 - 10:30
Oral Communications 3: Steroids
3B
Chairs: C Cummins (Toronto, Canada) & D Nanus (Birmingham)
09:00
OC3.1
Lack of 11β-hydroxysteroid dehydrogenase type 1 ameliorates the adverse features of Cushing’s syndrome
S Morgan
09:15
OC3.2
5α-Reductase is a regulator of glucocorticoid action and metabolic phenotype in human liver
M Nasiri
09:30
OC3.3
The 21-hydroxylase pseudogene may have a role in induction of tolerance to steroidogenic machinery
A Mitchell
09:45
OC3.4
Pre-receptor glucocorticoid metabolism across human ageing: the impact of gender and menopausal status
Z Hassan-Smith
10:00
OC3.5
Linking GWAS to gene function - CYP17A1 in hypertension
L Diver
10:15
OC3.6
Targeting of lysyl oxidase by steroids to reduce peritoneal fibrosis and scarring
C Harlow
09:00 - 10:30
Symposium 7: Natriuretic peptides: so much more than salt and water
1B
Chairs: C McArdle (Bristol) & S Mirczuk (London)
Novel functions for natriuretic peptides
09:00
S7.1
Guanylyl cyclases in cardiomyopathy
M Kuhn
(Wuerzburg, Germany)
09:30
S7.2
Natriuretic peptides in pituitary development and function
R Fowkes
10:00
S7.3
Natriuretic peptides in cardiovascular disease
A Hobbs
10:30 - 11:00
Tea & Coffee
Hall 2A
11:00 - 11:30
Plenary Lecture 1: Society for Endocrinology Dale Medal Lecture 2013
1A
Chair: A Grossman (Oxford)
PL1
Nuclear receptors, metabolism and the hunger games
R Evans
(La Jolla, USA)
11:30 - 12:00
Plenary Lecture 2: Society for Endocrinology Dale Medal Lecture 2014
1A
Chair: A Grossman (Oxford)
PL2
Coactivators: Master Genes for Physiology and Pathology
B O'Malley
(Pittsburg, USA)
12:00 - 14:00
Lunch & poster viewing
Odd-numbered posters attended 12:00 - 13:00; Even-numbered posters attended 13:00 - 14:00
Hall 2A
12:45 - 13:45
Ipsen Industry Sponsored Satellite Symposia
Optimising outcomes for patients with acromegaly and NETs
3AB
Chair: A Grossman (Oxford)
High-dose lanreotide Autogel for treatment-naive patients with acromegaly: the results of the PRIMARYS trial
J Bevan
SAGIT – A disease staging tool to personalise patient management for acromegaly
S Petersenn
(Hamburg, Germany)
New data confirming the beneficial role of lanreotide Autogel in the management of patients with a NET
Aled Rees
(Cardiff, United Kingdom)
14:00 - 15:30
Oral Communications 4: Thyroid and Bone
1C
Chairs: K Boelaert (Birmingham) & F Hannan (Liverpool)
14:00
OC4.1
Adaptor protein-2 sigma subunit mutations causing familial hypocalciuric hypercalcaemia type 3 exert dominant-negative effects
S Howles
14:15
OC4.2
PHOSPHO1: roles beyond skeletal mineralisation
K Oldknow
14:30
OC4.3
TRα mutation causes a severe and thyroxine-resistant skeletal dysplasia
J Bassett
14:45
OC4.4
Thyroid hormones stimulate osteoclastogenesis via TRα-dependent actions in osteoblasts
J Logan
15:00
OC4.5
A mutation in the 5’UTR of GNA11 causes familial hypocalciuric hypercalcemia type 2 (FHH2) due to reduced translational efficiency
S Howles
15:15
OC4.6
An ENU-induced Tyr265Stop mutation in Polg2 is associated with renal calcification in RCALC2 mice
Caroline Gorvin
(Birmingham, UK)
14:00 - 15:30
Young Endocrinologists' Symposium: Establishing successful collaborations
1B
Chairs: A Lansdown (Cardiff) & G Begum (Manchester)
Making the most of interdisciplinary collaborations and peer-to-peer networking
14:00
YE1.1
What makes a successful collaboration between a basic scientist and a clinician?
W Arlt
14:15
YE1.2
How do I talk to a bioinformatician/mathematician/engineer?
C McArdle
14:30
YE1.3
Industrial collaborations - where to start?
J Piner
14:45
YE1.4
Biobanking – what is it, and how could they be beneficial to me?
J Tobias
15:00
YE1.5
Peer-to-peer collaborations: Importance of YE groups
K Chapman
15:15
Panel discussion
14:00 - 15:30
Symposium 8: Chronic disease and growth
3B
Chairs: F Ahmed (Glasgow) & L Dunford (Leicester)
Chronic inflammation and growth hormone signalling
14:00
S8.1
Understanding growth hormone action through the growth plate
Colin Farquharson
14:30
S8.2
Targeting SOCS Proteins to Combat Inflammation
S Yarwood
15:00
S8.3
Managing abnormalities of growth in chronic disease
D Simon
(Paris, France)
14:00 - 15:30
Symposium 9: MEN1- from molecular pathology to therapies
Supported by Endocrine-Related Cancer and the Association of Multiple Endocrine Neoplasia Disorders
1A
Chairs: J Newell-Price (Sheffield) & G Walls (Oxford)
Current understanding and future perspectives in MEN1
14:00
S9.1
Current understanding and future perspectives in MEN1
S Agarwal
(Bethesda, USA)
14:30
S9.2
Genetics, pathophysiology and translational models of MEN1
Raj Thakker
(Oxford, United Kingdom)
15:00
S9.3
Practical management of patients with MEN1
B Skogseid
(Uppsala, Sweden)
15:30 - 16:00
Tea & Coffee
Hall 2A
16:00 - 16:45
Meet the Expert 3 (repeat)
Supported by Clinical Endocrinology and the Klinefelter’s Syndrome Association UK
3B
Chair: H Jones (Barnsley)
MTE3
Endocrine and non-endocrine management of Klinefelter's Syndrome (repeat)
Richard Quinton
(Newcastle, UK)
16:00 - 17:30
Oral Communications 5: Pituitary
1B
Chairs: J Davies (Manchester) & R Watkins (Birmingham)
16:00
OC5.1
Increased frequency and earlier onset of pituitary tumours in mice deleted for a multiple endocrine neoplasia type 1 (MEN1) allele and null for prolyl hydroxylase domain protein 1 (PHD1) (Men1+/-/Phd1-/-)
M Stevenson
16:15
OC5.2
Implications of the upregulation of lysine specific demethylase (LSD) 1 in the pathogenesis of pituitary adenomas
I Thompson
16:30
OC5.3
The Wnt/β-catenin effector Tcf3/TCF7L1 is required for normal hypothalamic-pituitary development and mutation in this gene is associated with congenital hypopituitarism
C Gaston-Massuet
16:45
OC5.4
GnRH pulse frequency-dependent regulation of ICER, a modulator of FSHβ transcription, is attenuated by MEKI/II blockade
I Thompson
17:00
OC5.5
Spatio-temporal analysis of prolactin gene transcription dynamics reveals short range co-ordination of lactotroph transcription activity in pituitary tissue
K Featherstone
17:15
OC5.6
A GH antagonist fusion with GH binding protein is biologically active, shows delayed clearance and inhibits growth in a rabbit model
I Wilkinson
16:00 - 17:30
Symposium 10: Fat and bone
Supported by Endocrine Connections and the Klinefelter’s Syndrome Association UK
1A
Chairs: P Dimitri (Sheffield) & R Crowley (Birmingham)
Body composition and bone
16:00
S10.1
Fat and its influence on bone
J Walsh
16:30
S10.2
Obesity and fractures - what is the inter-relationship?
J Compston
17:00
S10.3
Energy Deficiency, Amenorrhea and the Skeleton: Challenges and Therapies
16:45 - 17:30
Meet the Expert 5
Supported by Clinical Endocrinology
3B
Chair: P Trainer (Manchester)
MTE5
Pituitary replacement therapy
P Carroll
17:40 - 18:10
Plenary Lecture 3: Clinical Endocrinology Trust Visiting Professor Lecture
Supported by Clinical Endocrinology Trust
1A
Chair: J Connell (Dundee)
PL3
Adrenocortical tumours - from bench to bedside and back
Bruno Allolio
(Würzburg, Germany)
19:30 -
Conference dinner and Awards Ceremony
07:45 - 08:00
Breakfast
08:00 - 08:45
Meet the Expert 5 (repeat)
Supported by Clinical Endocrinology
1A
Chair: P Trainer (Manchester)
MTE5
Pituitary replacement therapy (repeat)
P Carroll
08:00 - 08:45
Meet the Expert 6
Supported by Clinical Endocrinology
3B
Chair: C Brain (London)
MTE6
Delayed puberty
J Blair
08:00 - 08:45
Meet the Expert 7
Supported by Clinical Endocrinology and the Thyroid Eye Disease Charitable Trust
1B
Chair: J Gilbert (London)
MTE7
Who should the endocrinologist ask the ophtalmologist to review?
Daniel Ezra
(London, UK)
08:00 - 08:45
Society for Endocrinology Journal Awards
1C
Chair: D Ray (Manchester)
08:00 - 08:09
JA 1
Society for Endocrinology Journal Award - Journal of Endocrinology: Mice deficient in PAPP-A show resistance to the development of diabetic nephropathy
C Conover
(Rochester, USA on behalf of the author group)
08:09 - 08:18
JA 2
Society for Endocrinology Journal Award - Journal of Molecular Endocrinology:Thyroid-specific inactivation of KIF3A alters TSH signaling pathway and leads to hypothyroidism
MC Many
(Louvain-la-Neuve, Belgium on behalf of the author group)
08:18 - 08:27
JA 3
Society for Endocrinology Journal Award - Endocrine-Related Cancer: Highly prevalent TERT promoter mutations in aggressive thyroid cancers
M Xing
(Baltimore, USA on behalf of the author group)
08:27 - 08:36
JA 4
Society for Endocrinology Journal Award - Clinical Endocrinology: What predicts adverse outcomes in untreated primary hyperparathyroidism? The Parathyroid Epidemiology and Audit Research Study (PEARS)
G Leese
08:36 - 08:45
JA 5
Society for Endocrinology Journal Award - Endocrine Connections: PKA regulatory subunit R2B is required for murine and human adipocyte differentiation
A Spada
(Milan, Italy on behalf of the author group)
08:45 - 09:25
Society for Endocrinology AGM
1A
09:30 - 11:00
Education Workshop 2: Practical publishing advice
3B
Chair: D Ray (Manchester)
09:30
EW2.1
Introduction
D Ray
09:35
EW2.2
Publishing ethics: Fabrication, Falsification and Plagiarism
A Clark
09:45
EW2.3
The peer review process
C Høybye
(Stockholm, Sweden)
09:55
EW2.4
Writing an attention grabbing abstract
F Weber
(Essen, Germany)
10:05
EW2.5
Responding to reviewer comments
S Ball
10:15
EW2.6
The art of scientific writing
Maralyn Druce
(London, UK)
10:25
EW2.7
Open Access
L Flook
10:35
Questions and discussion
09:30 - 11:00
Nurse Session 1 - Cushing's Syndrome
1B
Chairs: N Kieffer (Leicester) & J Andrew (Leeds)
09:30
N1.1
Investigating and Diagnosing Cushing’s Syndrome -not as straightforward as it seems?
K Meeran
09:55
N1.2
The role of the Endocrine Nurse in the Management of patients with Cushing’s syndrome
W Geilvoet
(Rotterdam, The Netherlands)
10:20
N1.3
Why do ‘cured’ Cushing’s patients need long-term follow up?
S Webb
(Barcelona, Spain)
10:45
N1.4
Cushing’s patient experience
A Patrick
09:30 - 11:00
Symposium 11: Some like it hot - new insights into brown adipose tissue
1C
Chairs: S O'Rahilly (Cambridge) & S Virtue (Cambridge)
Emerging biology of brown adipose tissue
09:30
S11.1
Mechanisms of brown adipocyte determination
P Seale
(Philadelphia, USA)
10:00
S11.2
The metabolic capacities of brown adipose tissue
B Cannon
(Stockholm, Sweden)
10:30
S11.3
How brown is human brown adipose tissue?
S Enerback
(Gothenburg, Sweden)
09:30 - 11:00
Clinical Management Workshop 3: Improving the care of young people in endocrinology
Supported by Clinical Endocrinology
1A
Chairs: H Gleeson (Leicester) & R El-Khairi (London)
09:30
CMW3.1
Adolescent health care in the UK in 2014
B White
10:00
CMW3.2
Adrenal replacement in adolescents and young adults
P Hindmarsh
(London, UK)
10:30
CMW3.3
Optimising bone health in adolescents and young adults
N Shaw
(Birmingham, UK)
11:00 - 11:30
Tea & Coffee
Exhibtion Hall
11:30 - 12:00
Plenary Lecture 4: Society for Endocrinology European Medal Lecture
1A
Chair: G Williams (London)
PL4
Mechanisms of thyroid hormone resistance
T Visser
(Rotterdam, Netherlands)
12:00 - 12:30
Plenary Lecture 5: Society for Endocrinology Transatlantic Medal Lecture
1A
Chair: D Ray (Manchester)
PL5
Transcriptional Coordination of Circadian and Metabolic Physiology
M Lazar
(Philadelphia, USA)
12:30 - 13:45
Lunch & poster viewing
Shortlisted posters attended
Hall 2A
12:45 - 13:45
Viropharma Industry Sponsored Satellite Symposia
New insights in the management of Adrenal Insufficiency in the UK
3AB
Chair: S Pearce (Newcastle-Upon-Tyne)
12:45 - 12:55
Introduction: The unmet medical need in adrenal insufficiency and the importance of circadian rhythm
S Pearce
(Newcastle, UK)
12:55 - 13:10
Adrenal Insufficiency today: the Salford project
P Trainer
13:10 - 13:25
Adrenal Insufficiency today: a report from the EU-AIR registry
Robert Murray
(Leeds, UK)
13:25 - 13:40
Patient cases and physician experience
R Pivonello
(Naples, Italy)
13:40 - 13:45
Closing remarks
S Pearce
(Newcastle, UK)
13:45 - 14:30
Meet the Expert 8
1C
Chair: C McCabe (Birmingham)
MTE8
Growing organs in the lab
A Mel
13:45 - 15:15
Nurses Session 2: The journey of endocrine nursing research: from evidence based practice to independent research
1B
Chairs: L Shephard (Birmingham) & V Fazal-Sanderson (Oxford)
13:45
N2.1
Background on the journey of endocrine nursing research
L Shepherd
13:50
N2.2
How to audit and evaluate your own practice
J Munday
14:15
N2.3
The role of the endocrine nurse in clinical trials
A Marland
14:40
N2.4
Independent nursing research
S Llahana
15:05
Questions and discussion
13:45 - 15:15
Symposium 12: Getting excited about sugar - the brain and blood glucose control
Supported by Endocrine Connections
1A
Chairs: R McCrimmon (Dundee) & B Challis (Cambridge)
How the brain orchestrates glucose metabolism
13:45
S12.1
How the brain senses blood glucose
M Evans
14:15
S12.2
Vagal control of energy metabolism
S Trapp
14:45
S12.3
Does glucagon need the brain for its effects on blood glucose?
R McCrimmon
13:45 - 15:15
Oral Communications 6: Clinical
3B
Chairs: R Semple (Cambridge) & A Puttanna (Walsall)
13:45
OC6.1
Adverse outcome in glucocorticoid-induced adrenal suppression; an analysis of short synacthen tests in 2782 patients
M Chapman
14:00
OC6.2
Localising parathyroid adenomas. Which imaging modality is best? Pre-operative localisation studies in patients with primary hyperparathyroidism: a large audit in a London tertiary centre
D Lewis
14:15
OC6.3
Sirolimus therapy for a patient with segmental overgrowth due to a mosaic activating mutation in phosphatidylinositol-3-kinase (PI3K)
V Parker
14:30
OC6.4
Reduced cognitive performance and altered white matter microstructure in young insulin-resistant women with polycystic ovary syndrome
M Udiawar
14:45
OC6.5
Effectiveness of metyrapone in 195 patients with Cushing’s syndrome
E Daniel
15:00
OC6.6
11C-Methionine PET-CT co-registered with volume MRI: a novel adjunctive imaging modality to aid diagnosis and management in patients with pituitary adenomas
O Koulouri
14:30 - 15:15
Meet the Expert 9
1C
Chairs: H Turner (Oxford) & P Hadoke (Edinburgh)
MTE9
Novel techniques to assess angiogenesis
S Germain
(Paris, France)
15:15 - 15:45
Tea & Coffee
Hall 2A
15:45 - 16:15
Oral Communication and Poster Prize Ceremony
1A
Chairs: A Grossman (Oxford) & C McCabe (Birmingham)
16:15 - 16:45
Plenary Lecture 6: British Tyroid Association Pitt-Rivers Lecture
Supported by Clinical Endocrinology Trust
1A
Chair: G Williams (London)
PL6
Disorders of thyroid hormone action: insights from human genetics
Krishna Chatterjee
(Cambridge, UK)
16:45 - 17:15
Plenary Lecture 7: Society for Endocrinology Medal Lecture
1A
Chair: D Ray (Manchester)
PL7
The clock in the pituitary gland: timing annual cycles
A Loudon
07:45 - 08:00
Breakfast
08:00 - 08:45
Meet the Expert 1 (repeat)
Supported by Clinical Endocrinology
1B
Chair: J Newell-Price (Sheffield)
MTE1
Medical management of Cushing's syndrome (repeat)
S Akker
08:00 - 08:45
Meet the Expert 2 (repeat)
Supported by Clinical Endocrinology
1C
Chair: N Gittoes (Birmingham)
MTE2
Vitamin D replacement: how much, how often and for whom? (repeat)
P Selby
08:45 - 09:15
Plenary Lecture 8: Clinical Endocrinology Trust Lecture
Supported by the Clinical Endocrinology Trust
1A
Chair: JS Bevan (Aberdeen)
PL8
Understanding glucocorticoid action, and the role of the glucocorticoid receptor
D Ray
09:15 - 09:45
Plenary Lecture 9: Society for Endocrinology Hoffenberg International Medal Lecture
1A
Chair: C McCabe (Birmingham)
PL9
Male Fertility Regulation; achievements and frustrations
R McLachlan
(Clayton, Australia)
09:45 - 10:15
Society for Endocrinology Emergency Endocrine Guidance
1A
Chair: J Franklyn (Birmingham)
SFE1.1
Acute Hypercalcaemia and Acute Hypocalcaemia
James Turner
(UK)
SFE1.2
Pituitary Apoplexy
S Baldeweg
10:15 - 10:45
Tea & Coffee
3AB
10:45 - 11:30
Meet the Expert 6 (repeat)
1B
Chair: C Brain (London)
MTE6
Delayed puberty (repeat)
J Blair
10:45 - 12:15
Clinical Management Workshop 4: Cardiovascular risk in endocrine disease
Supported by Endocrinology, Diabetes & Metabolism Case Reports and the Turner Syndrome Support Society
1A
Chairs: A Bates (Stourbridge) & J Thomas (Taunton)
10:45
CMW4.1
Cardiovascular risk in Turner's syndrome
M Donaldson
11:15
CMW4.2
Valvular disease in prolactinomas- weighing up the evidence
William Drake
(London, UK)
11:45
CMW4.3
Cardiovascular risk in childhood cancer survivors
E Crowne
10:45 - 12:45
Senior Endocrinologists' Session
1C
Chairs: B Cooke (Harpenden) & P Belchetz (Wetherby)
10:45
SE1.4
The Foundling Hospital
B Cooke
11:09
SE1.2
1776 Revolution in Liverpool. Matthew Dobson discovers Hyperglycaemia!
I MacFarlane
11:33
SE1.3
Macroprolacin - To seek or ignore : a Trans-Atlantic Divide
J McKenna
(Dublin, Ireland)
11:57
SE1.1
How important is luck for major discoveries?
J Tata
12:21
SE1.5
Steroid Merchants of Edinburgh
I Mason
11:30 - 12:15
Meet the Expert 7 (repeat)
Supported by Clinical Endocrinology and the Thyroid Eye Disease Charitable Trust
1B
Chair: J Gilbert (London)
MTE7
Whom should the endocrinologist ask the ophtalmologist to review? (repeat)
Daniel Ezra
(London, UK)
Thursday 27 March
61 sessions
07:45 - 08:00
Breakfast
07:45 -
Registration
08:00 - 08:45
Meet the Expert 1
Supported by Clinical Endocrinology
3B
Chair: J Newell-Price (Sheffield)
MTE1
Medical management of Cushing's syndrome
S Akker
08:00 - 08:45
Meet the Expert 2
Supported by Clinical Endocrinology
1A
Chair: N Gittoes (Birmingham)
MTE2
Vitamin D replacement: how much, how often and for whom?
P Selby
08:00 - 08:45
Meet the Expert 3
Supported by Clinical Endocrinology and the Klinefelter’s Syndrome Association UK
1B
Chair: H Jones (Barnsley)
MTE3
Endocrine and non-endocrine management of Klinefelter's Syndrome
Richard Quinton
(Newcastle, UK)
08:00 - 08:45
Meet the Expert 4
Supported by Clinical Endocrinology
1C
Chair: L Heisler (Cambridge)
MTE4
Optogenetics illuminates neuroendocrinology
D Burdakov
09:00 - 10:30
Symposium 6: Thyroid cell biology comes to your clinic
Supported by Journal of Molecular Endocrinology
1C
Chairs: C Spitzweg (Munich, Germany) & V Smith (Birmingham)
Emerging models of clinical relevance to thyroid disease
09:00
S6.1
Development of functional thyroid tissue from embryonic stem cells
Sabine Costagliola
(Brussels, Belgium)
09:30
S6.2
Factors involved in thyroid gland development and survival
R Lauro
10:00
S6.3
PBF signalling in thyroid tumourigenesis
Chris McCabe
(UK, Birmingham)
09:00 - 10:30
Clinical Management Workshop 2: How do I do it?
Supported by Endocrinology, Diabetes and Metabolism Case Reports CMW2.1 supported by Hypopara UK
1A
Chairs: J Ahlquist (Southend) & C Napier (Newcastle upon Tyne)
09:00
CMW2.1
How do I localise parathyroid tumours?
D Scott-Coombes
09:15
CMW2.2
How and when do I initiate treatment for central hypothyroidism?
L Persani
(Milan, Italy)
09:30
CMW2.3
How do I manage adrenal replacement in pregnancy?
W Arlt
09:45
CMW2.4
How do I investigate and manage sweating?
F Swords
10:00
CMW2.5
How and when do I treat the older male with a borderline testosterone?
F Wu
10:15
CMW2.6
How do I investigate and manage hyponatraemia?
S Ball
09:00 - 10:30
Oral Communications 3: Steroids
3B
Chairs: C Cummins (Toronto, Canada) & D Nanus (Birmingham)
09:00
OC3.1
Lack of 11β-hydroxysteroid dehydrogenase type 1 ameliorates the adverse features of Cushing’s syndrome
S Morgan
09:15
OC3.2
5α-Reductase is a regulator of glucocorticoid action and metabolic phenotype in human liver
M Nasiri
09:30
OC3.3
The 21-hydroxylase pseudogene may have a role in induction of tolerance to steroidogenic machinery
A Mitchell
09:45
OC3.4
Pre-receptor glucocorticoid metabolism across human ageing: the impact of gender and menopausal status
Z Hassan-Smith
10:00
OC3.5
Linking GWAS to gene function - CYP17A1 in hypertension
L Diver
10:15
OC3.6
Targeting of lysyl oxidase by steroids to reduce peritoneal fibrosis and scarring
C Harlow
09:00 - 10:30
Symposium 7: Natriuretic peptides: so much more than salt and water
1B
Chairs: C McArdle (Bristol) & S Mirczuk (London)
Novel functions for natriuretic peptides
09:00
S7.1
Guanylyl cyclases in cardiomyopathy
M Kuhn
(Wuerzburg, Germany)
09:30
S7.2
Natriuretic peptides in pituitary development and function
R Fowkes
10:00
S7.3
Natriuretic peptides in cardiovascular disease
A Hobbs
10:30 - 11:00
Tea & Coffee
Hall 2A
11:00 - 11:30
Plenary Lecture 1: Society for Endocrinology Dale Medal Lecture 2013
1A
Chair: A Grossman (Oxford)
PL1
Nuclear receptors, metabolism and the hunger games
R Evans
(La Jolla, USA)
11:30 - 12:00
Plenary Lecture 2: Society for Endocrinology Dale Medal Lecture 2014
1A
Chair: A Grossman (Oxford)
PL2
Coactivators: Master Genes for Physiology and Pathology
B O'Malley
(Pittsburg, USA)
12:00 - 14:00
Lunch & poster viewing
Odd-numbered posters attended 12:00 - 13:00; Even-numbered posters attended 13:00 - 14:00
Hall 2A
12:45 - 13:45
Ipsen Industry Sponsored Satellite Symposia
Optimising outcomes for patients with acromegaly and NETs
3AB
Chair: A Grossman (Oxford)
High-dose lanreotide Autogel for treatment-naive patients with acromegaly: the results of the PRIMARYS trial
J Bevan
SAGIT – A disease staging tool to personalise patient management for acromegaly
S Petersenn
(Hamburg, Germany)
New data confirming the beneficial role of lanreotide Autogel in the management of patients with a NET
Aled Rees
(Cardiff, United Kingdom)
14:00 - 15:30
Oral Communications 4: Thyroid and Bone
1C
Chairs: K Boelaert (Birmingham) & F Hannan (Liverpool)
14:00
OC4.1
Adaptor protein-2 sigma subunit mutations causing familial hypocalciuric hypercalcaemia type 3 exert dominant-negative effects
S Howles
14:15
OC4.2
PHOSPHO1: roles beyond skeletal mineralisation
K Oldknow
14:30
OC4.3
TRα mutation causes a severe and thyroxine-resistant skeletal dysplasia
J Bassett
14:45
OC4.4
Thyroid hormones stimulate osteoclastogenesis via TRα-dependent actions in osteoblasts
J Logan
15:00
OC4.5
A mutation in the 5’UTR of GNA11 causes familial hypocalciuric hypercalcemia type 2 (FHH2) due to reduced translational efficiency
S Howles
15:15
OC4.6
An ENU-induced Tyr265Stop mutation in Polg2 is associated with renal calcification in RCALC2 mice
Caroline Gorvin
(Birmingham, UK)
14:00 - 15:30
Young Endocrinologists' Symposium: Establishing successful collaborations
1B
Chairs: A Lansdown (Cardiff) & G Begum (Manchester)
Making the most of interdisciplinary collaborations and peer-to-peer networking
14:00
YE1.1
What makes a successful collaboration between a basic scientist and a clinician?
W Arlt
14:15
YE1.2
How do I talk to a bioinformatician/mathematician/engineer?
C McArdle
14:30
YE1.3
Industrial collaborations - where to start?
J Piner
14:45
YE1.4
Biobanking – what is it, and how could they be beneficial to me?
J Tobias
15:00
YE1.5
Peer-to-peer collaborations: Importance of YE groups
K Chapman
15:15
Panel discussion
14:00 - 15:30
Symposium 8: Chronic disease and growth
3B
Chairs: F Ahmed (Glasgow) & L Dunford (Leicester)
Chronic inflammation and growth hormone signalling
14:00
S8.1
Understanding growth hormone action through the growth plate
Colin Farquharson
14:30
S8.2
Targeting SOCS Proteins to Combat Inflammation
S Yarwood
15:00
S8.3
Managing abnormalities of growth in chronic disease
D Simon
(Paris, France)
14:00 - 15:30
Symposium 9: MEN1- from molecular pathology to therapies
Supported by Endocrine-Related Cancer and the Association of Multiple Endocrine Neoplasia Disorders
1A
Chairs: J Newell-Price (Sheffield) & G Walls (Oxford)
Current understanding and future perspectives in MEN1
14:00
S9.1
Current understanding and future perspectives in MEN1
S Agarwal
(Bethesda, USA)
14:30
S9.2
Genetics, pathophysiology and translational models of MEN1
Raj Thakker
(Oxford, United Kingdom)
15:00
S9.3
Practical management of patients with MEN1
B Skogseid
(Uppsala, Sweden)
15:30 - 16:00
Tea & Coffee
Hall 2A
16:00 - 16:45
Meet the Expert 3 (repeat)
Supported by Clinical Endocrinology and the Klinefelter’s Syndrome Association UK
3B
Chair: H Jones (Barnsley)
MTE3
Endocrine and non-endocrine management of Klinefelter's Syndrome (repeat)
Richard Quinton
(Newcastle, UK)
16:00 - 17:30
Oral Communications 5: Pituitary
1B
Chairs: J Davies (Manchester) & R Watkins (Birmingham)
16:00
OC5.1
Increased frequency and earlier onset of pituitary tumours in mice deleted for a multiple endocrine neoplasia type 1 (MEN1) allele and null for prolyl hydroxylase domain protein 1 (PHD1) (Men1+/-/Phd1-/-)
M Stevenson
16:15
OC5.2
Implications of the upregulation of lysine specific demethylase (LSD) 1 in the pathogenesis of pituitary adenomas
I Thompson
16:30
OC5.3
The Wnt/β-catenin effector Tcf3/TCF7L1 is required for normal hypothalamic-pituitary development and mutation in this gene is associated with congenital hypopituitarism
C Gaston-Massuet
16:45
OC5.4
GnRH pulse frequency-dependent regulation of ICER, a modulator of FSHβ transcription, is attenuated by MEKI/II blockade
I Thompson
17:00
OC5.5
Spatio-temporal analysis of prolactin gene transcription dynamics reveals short range co-ordination of lactotroph transcription activity in pituitary tissue
K Featherstone
17:15
OC5.6
A GH antagonist fusion with GH binding protein is biologically active, shows delayed clearance and inhibits growth in a rabbit model
I Wilkinson
16:00 - 17:30
Symposium 10: Fat and bone
Supported by Endocrine Connections and the Klinefelter’s Syndrome Association UK
1A
Chairs: P Dimitri (Sheffield) & R Crowley (Birmingham)
Body composition and bone
16:00
S10.1
Fat and its influence on bone
J Walsh
16:30
S10.2
Obesity and fractures - what is the inter-relationship?
J Compston
17:00
S10.3
Energy Deficiency, Amenorrhea and the Skeleton: Challenges and Therapies
16:45 - 17:30
Meet the Expert 5
Supported by Clinical Endocrinology
3B
Chair: P Trainer (Manchester)
MTE5
Pituitary replacement therapy
P Carroll
17:40 - 18:10
Plenary Lecture 3: Clinical Endocrinology Trust Visiting Professor Lecture
Supported by Clinical Endocrinology Trust
1A
Chair: J Connell (Dundee)
PL3
Adrenocortical tumours - from bench to bedside and back
Bruno Allolio
(Würzburg, Germany)
19:30 -
Conference dinner and Awards Ceremony
07:45 - 08:00
Breakfast
08:00 - 08:45
Meet the Expert 5 (repeat)
Supported by Clinical Endocrinology
1A
Chair: P Trainer (Manchester)
MTE5
Pituitary replacement therapy (repeat)
P Carroll
08:00 - 08:45
Meet the Expert 6
Supported by Clinical Endocrinology
3B
Chair: C Brain (London)
MTE6
Delayed puberty
J Blair
08:00 - 08:45
Meet the Expert 7
Supported by Clinical Endocrinology and the Thyroid Eye Disease Charitable Trust
1B
Chair: J Gilbert (London)
MTE7
Who should the endocrinologist ask the ophtalmologist to review?
Daniel Ezra
(London, UK)
08:00 - 08:45
Society for Endocrinology Journal Awards
1C
Chair: D Ray (Manchester)
08:00 - 08:09
JA 1
Society for Endocrinology Journal Award - Journal of Endocrinology: Mice deficient in PAPP-A show resistance to the development of diabetic nephropathy
C Conover
(Rochester, USA on behalf of the author group)
08:09 - 08:18
JA 2
Society for Endocrinology Journal Award - Journal of Molecular Endocrinology:Thyroid-specific inactivation of KIF3A alters TSH signaling pathway and leads to hypothyroidism
MC Many
(Louvain-la-Neuve, Belgium on behalf of the author group)
08:18 - 08:27
JA 3
Society for Endocrinology Journal Award - Endocrine-Related Cancer: Highly prevalent TERT promoter mutations in aggressive thyroid cancers
M Xing
(Baltimore, USA on behalf of the author group)
08:27 - 08:36
JA 4
Society for Endocrinology Journal Award - Clinical Endocrinology: What predicts adverse outcomes in untreated primary hyperparathyroidism? The Parathyroid Epidemiology and Audit Research Study (PEARS)
G Leese
08:36 - 08:45
JA 5
Society for Endocrinology Journal Award - Endocrine Connections: PKA regulatory subunit R2B is required for murine and human adipocyte differentiation
A Spada
(Milan, Italy on behalf of the author group)
08:45 - 09:25
Society for Endocrinology AGM
1A
09:30 - 11:00
Education Workshop 2: Practical publishing advice
3B
Chair: D Ray (Manchester)
09:30
EW2.1
Introduction
D Ray
09:35
EW2.2
Publishing ethics: Fabrication, Falsification and Plagiarism
A Clark
09:45
EW2.3
The peer review process
C Høybye
(Stockholm, Sweden)
09:55
EW2.4
Writing an attention grabbing abstract
F Weber
(Essen, Germany)
10:05
EW2.5
Responding to reviewer comments
S Ball
10:15
EW2.6
The art of scientific writing
Maralyn Druce
(London, UK)
10:25
EW2.7
Open Access
L Flook
10:35
Questions and discussion
09:30 - 11:00
Nurse Session 1 - Cushing's Syndrome
1B
Chairs: N Kieffer (Leicester) & J Andrew (Leeds)
09:30
N1.1
Investigating and Diagnosing Cushing’s Syndrome -not as straightforward as it seems?
K Meeran
09:55
N1.2
The role of the Endocrine Nurse in the Management of patients with Cushing’s syndrome
W Geilvoet
(Rotterdam, The Netherlands)
10:20
N1.3
Why do ‘cured’ Cushing’s patients need long-term follow up?
S Webb
(Barcelona, Spain)
10:45
N1.4
Cushing’s patient experience
A Patrick
09:30 - 11:00
Symposium 11: Some like it hot - new insights into brown adipose tissue
1C
Chairs: S O'Rahilly (Cambridge) & S Virtue (Cambridge)
Emerging biology of brown adipose tissue
09:30
S11.1
Mechanisms of brown adipocyte determination
P Seale
(Philadelphia, USA)
10:00
S11.2
The metabolic capacities of brown adipose tissue
B Cannon
(Stockholm, Sweden)
10:30
S11.3
How brown is human brown adipose tissue?
S Enerback
(Gothenburg, Sweden)
09:30 - 11:00
Clinical Management Workshop 3: Improving the care of young people in endocrinology
Supported by Clinical Endocrinology
1A
Chairs: H Gleeson (Leicester) & R El-Khairi (London)
09:30
CMW3.1
Adolescent health care in the UK in 2014
B White
10:00
CMW3.2
Adrenal replacement in adolescents and young adults
P Hindmarsh
(London, UK)
10:30
CMW3.3
Optimising bone health in adolescents and young adults
N Shaw
(Birmingham, UK)
11:00 - 11:30
Tea & Coffee
Exhibtion Hall
11:30 - 12:00
Plenary Lecture 4: Society for Endocrinology European Medal Lecture
1A
Chair: G Williams (London)
PL4
Mechanisms of thyroid hormone resistance
T Visser
(Rotterdam, Netherlands)
12:00 - 12:30
Plenary Lecture 5: Society for Endocrinology Transatlantic Medal Lecture
1A
Chair: D Ray (Manchester)
PL5
Transcriptional Coordination of Circadian and Metabolic Physiology
M Lazar
(Philadelphia, USA)
12:30 - 13:45
Lunch & poster viewing
Shortlisted posters attended
Hall 2A
12:45 - 13:45
Viropharma Industry Sponsored Satellite Symposia
New insights in the management of Adrenal Insufficiency in the UK
3AB
Chair: S Pearce (Newcastle-Upon-Tyne)
12:45 - 12:55
Introduction: The unmet medical need in adrenal insufficiency and the importance of circadian rhythm
S Pearce
(Newcastle, UK)
12:55 - 13:10
Adrenal Insufficiency today: the Salford project
P Trainer
13:10 - 13:25
Adrenal Insufficiency today: a report from the EU-AIR registry
Robert Murray
(Leeds, UK)
13:25 - 13:40
Patient cases and physician experience
R Pivonello
(Naples, Italy)
13:40 - 13:45
Closing remarks
S Pearce
(Newcastle, UK)
13:45 - 14:30
Meet the Expert 8
1C
Chair: C McCabe (Birmingham)
MTE8
Growing organs in the lab
A Mel
13:45 - 15:15
Nurses Session 2: The journey of endocrine nursing research: from evidence based practice to independent research
1B
Chairs: L Shephard (Birmingham) & V Fazal-Sanderson (Oxford)
13:45
N2.1
Background on the journey of endocrine nursing research
L Shepherd
13:50
N2.2
How to audit and evaluate your own practice
J Munday
14:15
N2.3
The role of the endocrine nurse in clinical trials
A Marland
14:40
N2.4
Independent nursing research
S Llahana
15:05
Questions and discussion
13:45 - 15:15
Symposium 12: Getting excited about sugar - the brain and blood glucose control
Supported by Endocrine Connections
1A
Chairs: R McCrimmon (Dundee) & B Challis (Cambridge)
How the brain orchestrates glucose metabolism
13:45
S12.1
How the brain senses blood glucose
M Evans
14:15
S12.2
Vagal control of energy metabolism
S Trapp
14:45
S12.3
Does glucagon need the brain for its effects on blood glucose?
R McCrimmon
13:45 - 15:15
Oral Communications 6: Clinical
3B
Chairs: R Semple (Cambridge) & A Puttanna (Walsall)
13:45
OC6.1
Adverse outcome in glucocorticoid-induced adrenal suppression; an analysis of short synacthen tests in 2782 patients
M Chapman
14:00
OC6.2
Localising parathyroid adenomas. Which imaging modality is best? Pre-operative localisation studies in patients with primary hyperparathyroidism: a large audit in a London tertiary centre
D Lewis
14:15
OC6.3
Sirolimus therapy for a patient with segmental overgrowth due to a mosaic activating mutation in phosphatidylinositol-3-kinase (PI3K)
V Parker
14:30
OC6.4
Reduced cognitive performance and altered white matter microstructure in young insulin-resistant women with polycystic ovary syndrome
M Udiawar
14:45
OC6.5
Effectiveness of metyrapone in 195 patients with Cushing’s syndrome
E Daniel
15:00
OC6.6
11C-Methionine PET-CT co-registered with volume MRI: a novel adjunctive imaging modality to aid diagnosis and management in patients with pituitary adenomas
O Koulouri
14:30 - 15:15
Meet the Expert 9
1C
Chairs: H Turner (Oxford) & P Hadoke (Edinburgh)
MTE9
Novel techniques to assess angiogenesis
S Germain
(Paris, France)
15:15 - 15:45
Tea & Coffee
Hall 2A
15:45 - 16:15
Oral Communication and Poster Prize Ceremony
1A
Chairs: A Grossman (Oxford) & C McCabe (Birmingham)
16:15 - 16:45
Plenary Lecture 6: British Tyroid Association Pitt-Rivers Lecture
Supported by Clinical Endocrinology Trust
1A
Chair: G Williams (London)
PL6
Disorders of thyroid hormone action: insights from human genetics
Krishna Chatterjee
(Cambridge, UK)
16:45 - 17:15
Plenary Lecture 7: Society for Endocrinology Medal Lecture
1A
Chair: D Ray (Manchester)
PL7
The clock in the pituitary gland: timing annual cycles
A Loudon
07:45 - 08:00
Breakfast
08:00 - 08:45
Meet the Expert 1 (repeat)
Supported by Clinical Endocrinology
1B
Chair: J Newell-Price (Sheffield)
MTE1
Medical management of Cushing's syndrome (repeat)
S Akker
08:00 - 08:45
Meet the Expert 2 (repeat)
Supported by Clinical Endocrinology
1C
Chair: N Gittoes (Birmingham)
MTE2
Vitamin D replacement: how much, how often and for whom? (repeat)
P Selby
08:45 - 09:15
Plenary Lecture 8: Clinical Endocrinology Trust Lecture
Supported by the Clinical Endocrinology Trust
1A
Chair: JS Bevan (Aberdeen)
PL8
Understanding glucocorticoid action, and the role of the glucocorticoid receptor
D Ray
09:15 - 09:45
Plenary Lecture 9: Society for Endocrinology Hoffenberg International Medal Lecture
1A
Chair: C McCabe (Birmingham)
PL9
Male Fertility Regulation; achievements and frustrations
R McLachlan
(Clayton, Australia)
09:45 - 10:15
Society for Endocrinology Emergency Endocrine Guidance
1A
Chair: J Franklyn (Birmingham)
SFE1.1
Acute Hypercalcaemia and Acute Hypocalcaemia